Search Results - "Yuan, Jiapei"
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1
Recurrently deregulated lncRNAs in hepatocellular carcinoma
Published in Nature communications (13-02-2017)“…Hepatocellular carcinoma (HCC) cells often invade the portal venous system and subsequently develop into portal vein tumour thrombosis (PVTT). Long noncoding…”
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2
Characterization of stress‐responsive lncRNAs in Arabidopsis thaliana by integrating expression, epigenetic and structural features
Published in The Plant journal : for cell and molecular biology (01-12-2014)“…Recently, in addition to poly(A)+ long non‐coding RNAs (lncRNAs), many lncRNAs without poly(A) tails, have been characterized in mammals. However, the…”
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3
The effects of coagulation factors on the risk of endometriosis: a Mendelian randomization study
Published in BMC medicine (25-05-2023)“…Endometriosis is recognized as a complex gynecological disorder that can cause severe pain and infertility, affecting 6-10% of all reproductive-aged women…”
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4
ChIPr: accurate prediction of cohesin-mediated 3D genome organization from 2D chromatin features
Published in Genome Biology (12-01-2024)“…The three-dimensional genome organization influences diverse nuclear processes. Here we present Chromatin Interaction Predictor (ChIPr), a suite of regression…”
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5
A compendium of genetic variations associated with promoter usage across 49 human tissues
Published in Nature communications (09-10-2024)“…Promoters play a crucial role in regulating gene transcription. However, our understanding of how genetic variants influence alternative promoter selection is…”
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6
Mitochondrial Trafficking and Processing of Telomerase RNA TERC
Published in Cell reports (Cambridge) (04-09-2018)“…Mitochondrial dysfunctions play major roles in many diseases. However, how mitochondrial stresses are relayed to downstream responses remains unclear. Here we…”
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7
InPACT: a computational method for accurate characterization of intronic polyadenylation from RNA sequencing data
Published in Nature communications (22-03-2024)“…Alternative polyadenylation can occur in introns, termed intronic polyadenylation (IPA), has been implicated in diverse biological processes and diseases, as…”
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8
Mitochondrion-processed TERC regulates senescence without affecting telomerase activities
Published in Protein & cell (01-09-2019)“…Mitochondrial dysfunctions play major roles in ageing. How mitochondrial stresses invoke downstream responses and how speci city of the signaling is achieved,…”
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An atlas of cell-type-specific interactome networks across 44 human tumor types
Published in Genome medicine (12-02-2024)“…Biological processes are controlled by groups of genes acting in concert. Investigating gene-gene interactions within different cell types can help researchers…”
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10
DIPAN: Detecting personalized intronic polyadenylation derived neoantigens from RNA sequencing data
Published in Computational and structural biotechnology journal (01-12-2024)“…Intronic polyadenylation (IPA) refers to a particular type of alternative polyadenylation where a gene makes use of a polyadenylation site located within its…”
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11
scAPAatlas: an atlas of alternative polyadenylation across cell types in human and mouse
Published in Nucleic acids research (07-01-2022)“…Abstract Alternative polyadenylation (APA) has been widely recognized as a crucial step during the post-transcriptional regulation of eukaryotic genes. Recent…”
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12
Stress‐responsive regulation of long non‐coding RNA polyadenylation in Oryza sativa
Published in The Plant journal : for cell and molecular biology (01-03-2018)“…Summary Recently, long non‐coding RNAs (lncRNAs) have been demonstrated to be involved in many biological processes of plants; however, a systematic study on…”
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13
Comprehensive characterization of somatic mutations associated with chimeric RNAs in human cancers
Published in International journal of cancer (15-08-2024)“…Chimeric RNAs, which can arise from gene recombination at the DNA level or non‐canonical splicing events at the RNA level, have been identified as important…”
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14
eaQTLdb: An atlas of enhancer activity quantitative trait loci across cancer types
Published in International journal of cancer (01-07-2023)“…Enhancers are key regulatory elements that exert crucial roles in diverse biological processes, including tumorigenesis and cancer development. Active…”
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15
Systematic characterization of novel lncRNAs responding to phosphate starvation in Arabidopsis thaliana
Published in BMC genomics (18-08-2016)“…Previously, several long non-coding RNAs (lncRNAs) were characterized as regulators in phosphate (Pi) starvation responses. However, systematic studies of…”
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16
Single-cell transcriptomic analysis of the immune microenvironment in pediatric acute leukemia
Published in Cancer letters (01-08-2024)“…Relapse and treatment resistance pose significant challenges in the management of pediatric B cell acute lymphoblastic leukemia (B-ALL) and acute myeloid…”
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Comprehensive analysis of long non-coding RNAs highlights their spatio-temporal expression patterns and evolutional conservation in Sus scrofa
Published in Scientific reports (24-02-2017)“…Despite modest sequence conservation and rapid evolution, long non-coding RNAs (lncRNAs) appear to be conserved in expression pattern and function. However,…”
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18
The landscape of RNA polymerase II-associated chromatin interactions in prostate cancer
Published in The Journal of clinical investigation (01-08-2020)“…Transcriptional dysregulation is a hallmark of prostate cancer (PCa). We mapped the RNA polymerase II-associated (RNA Pol II-associated) chromatin interactions…”
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19
Large-scale mapping of mammalian transcriptomes identifies conserved genes associated with different cell states
Published in Nucleic acids research (28-02-2017)“…Distinguishing cell states based only on gene expression data remains a challenging task. This is true even for analyses within a species. In cross-species…”
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Prostate Cancer Transcriptomic Regulation by the Interplay of Germline Risk Alleles, Somatic Mutations, and 3D Genomic Architecture
Published in Cancer discovery (02-12-2022)“…Prostate cancer is one of the most heritable human cancers. Genome-wide association studies have identified at least 185 prostate cancer germline risk alleles,…”
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