Search Results - "Yuan, Huating"
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CancerSEA: a cancer single-cell state atlas
Published in Nucleic acids research (08-01-2019)“…Abstract High functional heterogeneity of cancer cells poses a major challenge for cancer research. Single-cell sequencing technology provides an unprecedented…”
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DiseaseEnhancer: a resource of human disease-associated enhancer catalog
Published in Nucleic acids research (04-01-2018)“…Abstract Large-scale sequencing studies discovered substantial genetic variants occurring in enhancers which regulate genes via long range chromatin…”
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Individualized detection of TMPRSS2-ERG fusion status in prostate cancer: a rank-based qualitative transcriptome signature
Published in World journal of surgical oncology (09-02-2024)“…TMPRSS2-ERG (T2E) fusion is highly related to aggressive clinical features in prostate cancer (PC), which guides individual therapy. However, current fusion…”
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4
Dynamic regulatory networks of T cell trajectory dissect transcriptional control of T cell state transition
Published in Molecular therapy. Nucleic acids (03-12-2021)“…T cells exhibit heterogeneous functional states, which correlate with responsiveness to immune checkpoint blockade and prognosis of tumor patients. However,…”
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A pan‐cancer atlas of cancer hallmark‐associated candidate driver lncRNAs
Published in Molecular oncology (01-11-2018)“…Substantial cancer genome sequencing efforts have discovered many important driver genes contributing to tumorigenesis. However, very little is known about the…”
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TIP: A Web Server for Resolving Tumor Immunophenotype Profiling
Published in Cancer research (Chicago, Ill.) (01-12-2018)“…: Systematically tracking the tumor immunophenotype is required to understand the mechanisms of cancer immunity and improve clinical benefit of cancer…”
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Breast cancer prognosis signature: linking risk stratification to disease subtypes
Published in Briefings in bioinformatics (27-11-2019)“…Abstract Breast cancer is a very complex and heterogeneous disease with variable molecular mechanisms of carcinogenesis and clinical behaviors. The…”
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Decoding the associations between cell functional states in head and neck cancer based on single-cell transcriptome
Published in Oral oncology (01-11-2022)“…•Six cell states, including EMT, immune response, epithelial differentiation, stress, G1/S and G2/M phases were identified in HNSCC.•The association patterns…”
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The Heterogeneous Cellular States of Glioblastoma Stem Cells Revealed by Single Cell Analysis
Published in Stem cells (Dayton, Ohio) (02-03-2023)“…Glioblastoma stem cells (GSCs) contributed to the progression, treatment resistance, and relapse of glioblastoma (GBM). However, current researches on GSCs…”
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Discovering Rare Genes Contributing to Cancer Stemness and Invasive Potential by GBM Single-Cell Transcriptional Analysis
Published in Cancers (16-12-2019)“…Single-cell RNA sequencing presents the sophisticated delineation of cell transcriptomes in many cancer types and highlights the tumor heterogeneity at higher…”
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11
A pan‐cancer atlas of cancer hallmark‐associated candidate driver lnc RNA s
Published in Molecular oncology (01-11-2018)“…Substantial cancer genome sequencing efforts have discovered many important driver genes contributing to tumorigenesis. However, very little is known about the…”
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Optimizing prognosis-related key miRNA-target interactions responsible for cancer metastasis
Published in Oncotarget (12-12-2017)“…Increasing evidence suggests that the abnormality of microRNAs (miRNAs) and their downstream targets is frequently implicated in the pathogenesis of human…”
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