Search Results - "Yu, Yuanhuan"
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A non-invasive far-red light-induced split-Cre recombinase system for controllable genome engineering in mice
Published in Nature communications (24-07-2020)“…The Cre- loxP recombination system is a powerful tool for genetic manipulation. However, there are widely recognized limitations with chemically inducible Cre-…”
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Synthetic far-red light-mediated CRISPR-dCas9 device for inducing functional neuronal differentiation
Published in Proceedings of the National Academy of Sciences - PNAS (17-07-2018)“…The ability to control the activity of CRISPR-dCas9 with precise spatiotemporal resolution will enable tight genome regulation of user-defined endogenous genes…”
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3
Optogenetic-controlled immunotherapeutic designer cells for post-surgical cancer immunotherapy
Published in Nature communications (26-10-2022)“…Surgical resection is the main treatment option for most solid tumors, yet cancer recurrence after surgical resection remains a significant challenge in cancer…”
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4
AAV-delivered muscone-induced transgene system for treating chronic diseases in mice via inhalation
Published in Nature communications (06-02-2024)“…Gene therapies provide treatment options for many diseases, but the safe and long-term control of therapeutic transgene expression remains a primary issue for…”
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Engineering a far-red light-activated split-Cas9 system for remote-controlled genome editing of internal organs and tumors
Published in Science advances (01-07-2020)“…It is widely understood that CRISPR-Cas9 technology is revolutionary, with well-recognized issues including the potential for off-target edits and the…”
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Author Correction: Optogenetic-controlled immunotherapeutic designer cells for post-surgical cancer immunotherapy
Published in Nature communications (01-05-2024)Get full text
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Constructing a Smartphone-Controlled Semiautomatic Theranostic System for Glucose Homeostasis in Diabetic Mice
Published in Methods in molecular biology (Clifton, N.J.) (2021)“…With the development of mobile communication technology, smartphones have been used in point-of-care technologies (POCTs) as an important part of telemedicine…”
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Smartphone-controlled optogenetically engineered cells enable semiautomatic glucose homeostasis in diabetic mice
Published in Science translational medicine (26-04-2017)“…With the increasingly dominant role of smartphones in our lives, mobile health care systems integrating advanced point-of-care technologies to manage chronic…”
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A Synthetic-Biology-Inspired Therapeutic Strategy for Targeting and Treating Hepatogenous Diabetes
Published in Molecular therapy (01-02-2017)“…Hepatogenous diabetes is a complex disease that is typified by the simultaneous presence of type 2 diabetes and many forms of liver disease. The chief…”
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Fabrication of novel double-hetero-epitaxial SOI structure Si/γ-Al2O3/Si
Published in Journal of crystal growth (2003)Get full text
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Sonogenetics-controlled synthetic designer cells for cancer therapy in tumor mouse models
Published in Cell reports. Medicine (21-05-2024)“…Bacteria-based therapies are powerful strategies for cancer therapy, yet their clinical application is limited by a lack of tunable genetic switches to safely…”
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Very low-pressure VLP-CVD growth of high quality γ-Al2O3 films on silicon by multi-step process
Published in Journal of crystal growth (01-03-2002)Get full text
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Comparison of properties of solid phase epitaxial silicon on sapphire films recrystallized by rapid thermal annealing and furnace annealing
Published in Materials science & engineering. B, Solid-state materials for advanced technology (1995)“…Chemically vapour deposited silicon on sapphire (SOS) films 0.25 μm thick were implanted with 28Si + and recrystallized in solid phase by furnace annealing…”
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Journal Article Conference Proceeding -
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Fabrication of novel double-hetero-epitaxial SOI structure Si/γ-Al 2O 3/Si
Published in Journal of crystal growth (2003)“…In this paper, we report the fabrication of Si-based double-hetero-epitaxial silicon on insulator (SOI) structure Si/γ-Al 2O 3/Si. Firstly, single crystalline…”
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Journal Article -
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Very low-pressure VLP-CVD growth of high quality γ-Al 2O 3 films on silicon by multi-step process
Published in Journal of crystal growth (2002)“…γ-Al 2O 3 films were grown on Si (1 0 0) substrates using the sources of TMA (Al(CH 3) 3) and O 2 by very low-pressure chemical vapor deposition. The effects…”
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Journal Article -
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Improvement of CMOS/SOS devices characteristics by a modified solid phase epitaxy
Published in 1998 5th International Conference on Solid-State and Integrated Circuit Technology. Proceedings (Cat. No.98EX105) (1998)“…CMOS/SOS devices have lower carrier mobility and higher channel leakage current than bulk silicon CMOS devices. These mainly result from the defects in the…”
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Conference Proceeding