Search Results - "Yu, Xiao‐Hua"

An adaptive filtering approach for electrocardiogram (ECG) signal noise reduction using neural networks by Poungponsri, Suranai, Yu, Xiao-Hua

“…Electrocardiogram (ECG) signals have been widely used in clinical studies to detect heart diseases. However, ECG signals are often contaminated with noise such…”
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Hepatic cholesterol transport and its role in non-alcoholic fatty liver disease and atherosclerosis by Li, Heng, Yu, Xiao-Hua, Ou, Xiang, Ouyang, Xin-Ping, Tang, Chao-Ke

“…Non-alcoholic fatty liver disease (NAFLD) is a quickly emerging global health problem representing the most common chronic liver disease in the world…”
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Itaconate: an emerging determinant of inflammation in activated macrophages by Yu, Xiao‐Hua, Zhang, Da‐Wei, Zheng, Xi‐Long, Tang, Chao‐Ke

“…Macrophages play a central role in innate immunity as the first line of defense against pathogen infection. Upon exposure to inflammatory stimuli, macrophages…”
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LncRNA kcnq1ot1 promotes lipid accumulation and accelerates atherosclerosis via functioning as a ceRNA through the miR-452-3p/HDAC3/ABCA1 axis by Yu, Xiao-Hua, Deng, Wen-Yi, Chen, Jiao-Jiao, Xu, Xiao-Dan, Liu, Xian-Xia, Chen, Lei, Shi, Meng-Wen, Liu, Qi-Xian, Tao, Min, Ren, Kun

“…Kcnq1 overlapping transcript 1 (kcnq1ot1), an imprinted antisense lncRNA in the kcnq1 locus, acts as a potential contributor to cardiovascular disease, but its…”
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Zinc finger E‐box binding homeobox 1 and atherosclerosis: New insights and therapeutic potential by Li, Heng, Zou, Jin, Yu, Xiao‐Hua, Ou, Xiang, Tang, Chao‐Ke

“…Zinc finger E‐box binding homeobox 1 (ZEB1), an important transcription factor belonging to the ZEB family, plays a crucial role in regulating gene expression…”
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CTRP12 ameliorates atherosclerosis by promoting cholesterol efflux and inhibiting inflammatory response via the miR-155-5p/LXRα pathway by Wang, Gang, Chen, Jiao-Jiao, Deng, Wen-Yi, Ren, Kun, Yin, Shan-Hui, Yu, Xiao-Hua

“…C1q tumor necrosis factor-related protein 12 (CTRP12), a conserved paralog of adiponectin, is closely associated with cardiovascular disease. However, little…”
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lncRNAs: novel players in intervertebral disc degeneration and osteoarthritis by Chen, Wen‐Kang, Yu, Xiao‐Hua, Yang, Wei, Wang, Cheng, He, Wen‐Si, Yan, Yi‐Guo, Zhang, Jian, Wang, Wen‐Jun

“…The term long non‐coding RNA (lncRNA) refers to a group of RNAs with length more than 200 nucleotides, limited protein‐coding potential, and having widespread…”
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C1q tumor necrosis factor-related protein 9 in atherosclerosis: Mechanistic insights and therapeutic potential by Yu, Xiao-Hua, Zhang, Da-Wei, Zheng, Xi-Long, Tang, Chao-Ke

“…C1q tumor necrosis factor-related protein 9 (CTRP9), a newly discovered adipokine, is the closest paralog of adiponectin. After proteolytic cleavage, it can…”
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CXCL12 promotes atherosclerosis by downregulating ABCA1 expression via the CXCR4/GSK3β/β-cateninT120/TCF21 pathway by Gao, Jia-Hui, He, Lin-Hao, Yu, Xiao-Hua, Zhao, Zhen-Wang, Wang, Gang, Zou, Jin, Wen, Feng-Jiao, Zhou, Li, Wan, Xiang-Jun, Zhang, Da-Wei, Tang, Chao-Ke

“…CXC chemokine ligand 12 (CXCL12) is a member of the CXC chemokine family and mainly acts on cell chemotaxis. CXCL12 also elicits a proatherogenic role, but the…”
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CTRP1 decreases ABCA1 expression and promotes lipid accumulation through the miR‐424‐5p/FoxO1 pathway in THP‐1 macrophage‐derived foam cells by Zhang, Zi‐Zhen, Chen, Jiao‐Jiao, Deng, Wen‐Yi, Yu, Xiao‐Hua, Tan, Wei‐Hua

“…Prevention of ATP binding cassette transporter A1 (ABCA1)‐dependent cholesterol efflux leads to lipid accumulation in macrophages and atherosclerosis…”
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Apelin and its receptor APJ in cardiovascular diseases by Yu, Xiao-Hua, Tang, Zhi-Bin, Liu, Li-Jing, Qian, Hong, Tang, Shi-Lin, Zhang, Da-Wei, Tian, Guo-Ping, Tang, Chao-Ke

“…Apelin is an adipokine that has been identified as an endogenous ligand for the orphan receptor APJ. Apelin and APJ are expressed in a diverse range of tissues…”
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Inhibition of the immunoproteasome LMP2 ameliorates ischemia/hypoxia-induced blood-brain barrier injury through the Wnt/β-catenin signalling pathway by Chen, Xing-Yong, Wan, Shao-Fen, Yao, Nan-Nan, Lin, Ze-Jing, Mao, Yan-Guang, Yu, Xiao-Hua, Wang, Yin-Zhou

“…Disruption of the blood-brain barrier (BBB) after a stroke can lead to brain injury and neurological impairment. Previous work confirmed the involvement of the…”
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Pregnancy-Associated Plasma Protein-A Accelerates Atherosclerosis by Regulating Reverse Cholesterol Transport and Inflammation by Tang, Shi-Lin, Zhao, Zhen-Wang, Liu, Shang-Ming, Wang, Gang, Yu, Xiao-Hua, Zou, Jin, Wang, Si-Qi, Dai, Xiao-Yan, Fu, Min-Gui, Zheng, Xi-Long, Zhang, Da-Wei, Fu, Hui, Tang, Chao-Ke

“…Background: Recent studies have suggested that pregnancy-associated plasma protein-A (PAPP-A) is involved in the pathogenesis of atherosclerosis. This study…”
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Phenotypic expansion of KCNH1‐associated disorders to include isolated epilepsy and its associations with genotypes and molecular sub‐regional locations by Tian, Mao‐Qiang, Li, Ren‐Ke, Yang, Fan, Shu, Xiao‐Mei, Li, Juan, Chen, Jing, Peng, Long‐Ying, Yu, Xiao‐Hua, Yang, Chang‐Jian

“…Purpose Genotype‐phenotypic correlation of KCNH1 variant remains elusive. This study aimed to expand the phenotypic spectrum of KCNH1 and explore the…”
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Pregnancy-associated plasma protein-A in atherosclerosis: Molecular marker, mechanistic insight, and therapeutic target by Yu, Xiao-Hua, He, Lin-Hao, Gao, Jia-Hui, Zhang, Da-Wei, Zheng, Xi-Long, Tang, Chao-Ke

“…Pregnancy-associated plasma protein-A (PAPP-A), a member of the metzincin metalloproteinase superfamily, can enhance local insulin-like growth factor (IGF)…”
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TIGAR mitigates atherosclerosis by promoting cholesterol efflux from macrophages by Zhao, Zhen-Wang, Zhang, Min, Zou, Jin, Wan, Xiang-Jun, Zhou, Li, Wu, Yao, Liu, Shang-Ming, Liao, Ling-Xiao, Li, Heng, Qin, Yu-Sheng, Yu, Xiao-Hua, Tang, Chao-Ke

“…TP53-induced glycolysis and apoptosis regulator (TIGAR) is now characterized as a fructose-2,6-bisphosphatase to reduce glycolysis and protect against…”
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Biochanin A Mitigates Atherosclerosis by Inhibiting Lipid Accumulation and Inflammatory Response by Ren, Kun, Liu, Qi-Xian, Xu, Xiao-Dan, Deng, Wen-Yi, Chen, Jiao-Jiao, Yu, Xiao-Hua, Shi, Meng-Wen

“…Biochanin A (BCA), a dietary isoflavone extracted from red clover and cabbage, has been shown to antagonize hypertension and myocardial ischemia/reperfusion…”
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Endocan: A Key Player of Cardiovascular Disease by Chen, Jinzhi, Jiang, Liping, Yu, Xiao-Hua, Hu, Mi, Zhang, Yang-Kai, Liu, Xin, He, Pingping, Ouyang, Xinping

“…Endothelial dysfunction is considered to be an early change in atherosclerosis. Endocan, also known as endothelial cell specific molecule-1, is a soluble…”
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Heat shock protein 70 accelerates atherosclerosis by downregulating the expression of ABCA1 and ABCG1 through the JNK/Elk-1 pathway by Zhao, Zhen-Wang, Zhang, Min, Chen, Ling-Yan, Gong, Duo, Xia, Xiao-Dan, Yu, Xiao-Hua, Wang, Si-Qi, Ou, Xiang, Dai, Xiao-Yan, Zheng, Xi-Long, Zhang, Da-Wei, Tang, Chao-Ke

“…Recent studies have suggested that heat shock protein 70 (HSP70) may play critical roles in cardiovascular disease. However, the effects of HSP70 on the…”
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MicroRNA-377 Inhibits Atherosclerosis by Regulating Triglyceride Metabolism Through the DNA Methyltransferase 1 in Apolipoprotein E-Knockout Mice by Chen, Ling-Yan, Xia, Xiao-Dan, Zhao, Zhen-Wang, Gong, Duo, Ma, Xiao-Feng, Yu, Xiao-Hua, Zhang, Qiang, Wang, Si-Qi, Dai, Xiao-Yan, Zheng, Xi-Long, Zhang, Da-Wei, Yin, Wei-Dong, Tang, Chao-Ke

“…Background: Lipoprotein lipase (LPL) plays an important role in triglyceride metabolism. It is translocated across endothelial cells to reach the luminal…”
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