Search Results - "Yu, Wenkui"
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Lipid desaturation-associated endoplasmic reticulum stress regulates MYCN gene expression in hepatocellular carcinoma cells
Published in Cell death & disease (27-01-2020)“…Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths worldwide due to its high rate of recurrence, in part because of cancer…”
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2
Metagenomic next-generation sequencing in the diagnosis of severe pneumonias caused by Chlamydia psittaci
Published in Infection (01-08-2020)“…Purpose Chlamydia psittaci infection in humans can lead to serious clinical manifestations, including severe pneumonia, adult respiratory distress syndrome,…”
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3
Diaphragm thickness on computed tomography for nutritional assessment and hospital stay prediction in critical COVID-19
Published in Asia Pacific Journal of Clinical Nutrition (01-03-2022)“…Background and Objectives: To evaluate the significance of diaphragm thickness (DT) in assessing the nutritional status and predicting the length of hospital…”
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4
Targeting connexin 43 provides anti-inflammatory effects after intracerebral hemorrhage injury by regulating YAP signaling
Published in Journal of neuroinflammation (28-10-2020)“…Abstract Background In the central nervous system (CNS), connexin 43 (Cx43) is mainly expressed in astrocytes and regulates astrocytic network homeostasis…”
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Exogenous Melatonin Alleviates Skeletal Muscle Wasting by Regulating Hypothalamic Neuropeptides Expression in Endotoxemia Rats
Published in Neurochemical research (01-04-2022)“…To investigate whether exogenous melatonin (MLT) could alleviate skeletal muscle wasting by regulating hypothalamic neuropeptides expression. Adult male…”
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6
Imaging of the ex vivo transglutaminase activity in liver macrophages of sepsis mice
Published in Analytical biochemistry (15-05-2020)“…Sepsis is the leading cause of death in hospitalized patients and is characterized by a dysregulated inflammatory response to infection and multiple organ…”
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Acute muscle wasting rate assessment and long-term mortality in critically ill trauma
Published in Asia Pacific Journal of Clinical Nutrition (01-12-2023)“…Background and Objectives: To evaluate the relationship between acute muscle wasting rate and long-term mortality in critically ill trauma. Methods and Study…”
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8
Hederagenin Attenuates Cerebral Ischaemia/Reperfusion Injury by Regulating MLK3 Signalling
Published in Frontiers in pharmacology (30-07-2020)“…Cerebral ischaemia/reperfusion (CI/R) injury is a major challenge due to the lack of effective neuroprotective drugs. Hederagenin (HE) is the aglycone part of…”
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Mouse Model of Critical Persistent Inflammation, Immunosuppression, and Catabolism Syndrome
Published in Shock (Augusta, Ga.) (01-02-2022)“…Persistent inflammation, immunosuppression, and catabolism syndrome (PIICS) is a growing challenge in intensive care units (ICUs). PIICS causes a severe…”
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10
Anti-inflammatory Effect of Ginsenoside Rb1 Contributes to the Recovery of Gastrointestinal Motility in the Rat Model of Postoperative Ileus
Published in Biological & pharmaceutical bulletin (01-11-2014)“…Ginsenoside Rb1 (GRb1), one of the principle active components of Panax ginseng, has been reported to reduce inflammation in various diseases. In the present…”
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Novel fast pathogen diagnosis method for severe pneumonia patients in the intensive care unit: randomized clinical trial
Published in eLife (07-10-2022)“…Background: Severe pneumonia is one of the common acute diseases caused by pathogenic microorganism infection, especially by pathogenic bacteria, leading to…”
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12
Using Digestive Fluid Biomarkers to Predict Acute Gastrointestinal Injury in Critically Ill Patients: A Pilot Study
Published in American journal of critical care (01-11-2018)“…Acute gastrointestinal injury is associated with significantly increased mortality in critically ill patients. However, markers for measuring acute…”
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13
The Pathophysiology and Management of Acute Traumatic Coagulopathy
Published in Clinical and applied thrombosis/hemostasis (01-10-2015)“…Acute traumatic coagulopathy (ATC) is commonly seen among patients with severe injury and will lead to uncontrolled bleeding diathesis, which is an important…”
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14
Berberine Ameliorates Intestinal Mucosal Barrier Damage Induced by Peritoneal Air Exposure
Published in Biological & pharmaceutical bulletin (01-01-2015)“…Berberine, an isoquinoline alkaloid derived from many medicinal plants, has been extensively used to treat various gastrointestinal diseases. In the present…”
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Subcutaneous Adipose Tissue Is Associated with Acute Kidney Injury after Abdominal Trauma Based on the Generalized Propensity Score Approach: A Retrospective Cohort Study
Published in Obesity facts (2023)“…Introduction: Obesity is associated with an increased risk of acute kidney injury (AKI) after trauma. However, the associations between different adipose…”
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16
Rapid Identification of Pathogens in Severe Pneumonia by Species-specific Bacterial Detector (SSBD)
Published in Bio-protocol (20-05-2023)“…Fast and accurate detection of pathogenic bacterial infection in patients with severe pneumonia is significant to its treatment. The traditional culture method…”
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Comparison of the effects of different calorie amounts of enteral nutrition in hypercatabolism associated with ghrelin-POMC in endotoxemic rats
Published in Nutrition & metabolism (15-04-2022)“…Hypercatabolism often occurs in critically ill patients, and it increases infection rates and mortality in these patients. Enteral nutrition (EN) is commonly…”
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Akkermansia muciniphila Alleviates Persistent Inflammation, Immunosuppression, and Catabolism Syndrome in Mice
Published in Metabolites (28-01-2023)“…Many patients in intensive care units, especially the elderly, suffer from chronic critical illness and exhibit a new pathophysiological phenotype: persistent…”
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Clinical Features of Fatal Pandemic Influenza A/H1N1 Infection Complicated by Invasive Pulmonary Fungal Infection
Published in Mycopathologia (1975) (01-04-2020)“…Background Severe pneumonia caused by influenza virus infection can be secondary to invasive pulmonary fungal (IPF) infection. Objectives This study aimed to…”
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Dexmedetomidine ameliorates muscle wasting and attenuates the alteration of hypothalamic neuropeptides and inflammation in endotoxemic rats
Published in PloS one (30-03-2017)“…Dexmedetomidine is generally used for sedaton in critically ill, it could shorten duration of mechanical ventilation, ICU stay and lower basic metabolism…”
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