Search Results - "Yu, T. R"
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Arctigenin, a natural compound, activates AMP-activated protein kinase via inhibition of mitochondria complex I and ameliorates metabolic disorders in ob/ob mice
Published in Diabetologia (01-05-2012)“…Aims/hypothesis Arctigenin is a natural compound that had never been previously demonstrated to have a glucose-lowering effect. Here it was found to activate…”
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2
Phytochemical Constituents of Arenaria kansuensis
Published in Chemistry of natural compounds (01-05-2019)Get full text
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Caspase 3, periodically expressed and activated at G2/M transition, is required for nocodazole-induced mitotic checkpoint
Published in Apoptosis (London) (01-05-2006)“…Caspases have been known for several years for their involvement in executing apoptosis, where unwanted or damaged cells are eliminated. Surprisingly, after…”
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Theta-frequency phase-locking of single anterior cingulate cortex neurons and synchronization with the medial thalamus are modulated by visceral noxious stimulation in rats
Published in Neuroscience (09-07-2015)“…Highlights • Repetitive colorectal distention induced visceral hypersensitivity and ACC sensitization. • Theta band power in the ACC was modulated by…”
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Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity
Published in Cell (18-04-2003)“…In contrast to the well-established roles of PPARγ and PPARα in lipid metabolism, little is known for PPARδ in this process. We show here that targeted…”
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Expression and function of orphan nuclear receptor TLX in adult neural stem cells
Published in Nature (01-01-2004)“…The finding of neurogenesis in the adult brain led to the discovery of adult neural stem cells. TLX was initially identified as an orphan nuclear receptor…”
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Cell-Type-Specific Regulation of the Retinoic Acid Receptor Mediated by the Orphan Nuclear Receptor TLX
Published in Molecular and Cellular Biology (01-12-2000)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Hypodense eosinophil number relates to clinical severity, airway hyperresponsiveness and response to inhaled corticosteroids in asthmatic subjects
Published in The European respiratory journal (01-08-1994)“…The phenotypically distinct low-density eosinophil, with its greater inflammatory potential, is increased in asthma. However, the role of hypodense eosinophils…”
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Tlx and Pax6 co-operate genetically to establish the pallio-subpallial boundary in the embryonic mouse telencephalon
Published in Development (Cambridge) (01-03-2003)“…We have examined the role of Tlx , an orphan nuclear receptor, in dorsal-ventral patterning of the mouse telencephalon. Tlx is expressed broadly in the…”
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MPZ mutation G123S characterization : Evidence for a complex pathogenesis in CMT disease
Published in Neurology (22-01-2008)“…To characterize the clinical and cellular phenotypes of a novel MPZ mutation identified in a Chinese family with Charcot-Marie-Tooth (CMT) disease type 1B. The…”
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Relationship between Drosophila gap gene tailless and a vertebrate nuclear receptor Tlx
Published in Nature (London) (04-08-1994)“…We report here the identification of a unique vertebrate nuclear receptor, Tlx, which is expressed exclusively in the neuroepithelium of the embryonic brain…”
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Identification of a Photoreceptor Cell-Specific Nuclear Receptor
Published in Proceedings of the National Academy of Sciences - PNAS (27-04-1999)“…Nuclear receptors comprise a large and expanding family of transcription factors involved in diverse aspects of animal physiology and development, the…”
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The Orphan Nuclear Receptor Tlx Regulates Pax2 and Is Essential for Vision
Published in Proceedings of the National Academy of Sciences - PNAS (14-03-2000)“…Although the development of the vertebrate eye is well described, the number of transcription factors known to be key to this process is still limited. The…”
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A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis
Published in Cell metabolism (03-11-2020)“…Dysregulation of the gut microbiome has been implicated in the progression of non-alcoholic fatty liver disease (NAFLD) to advanced fibrosis and cirrhosis. To…”
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AMPK and PPARδ Agonists Are Exercise Mimetics
Published in Cell (08-08-2008)“…The benefits of endurance exercise on general health make it desirable to identify orally active agents that would mimic or potentiate the effects of exercise…”
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Segmentation Gene Product Fushi Tarazu is an LXXLL Motif-Dependent Coactivator for Orphan Receptor FTZ-F1
Published in Proceedings of the National Academy of Sciences - PNAS (23-10-2001)“…Orphan receptors for whom cognate ligands have not yet been identified form a large subclass within the nuclear receptor superfamily. To address one aspect of…”
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Nuclear structure-associated TIF2 recruits glucocorticoid receptor and its target DNA
Published in Biochemical and biophysical research communications (16-07-2004)“…Assembly of multi-protein complexes on promoter and enhancer elements is a prerequisite for onset of gene transcription. At the beginning of this process,…”
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Synthesis of Dendritic Polymer for Hydrogen Peroxide Production and Organic Pollutants Degradation Under Visible Light Conditions
Published in ChemistrySelect (Weinheim) (04-09-2024)“…A process for photocatalytically synthesizing hydrogen peroxide while simultaneously degrading organic pollutants is of interest. In this study, a dendritic…”
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A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis
Published in Cell metabolism (03-11-2020)Get full text
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20
Genetic toxicity of cocaine
Published in Carcinogenesis (New York) (01-07-1999)“…Cocaine is a widely abused drug. Recently, it has been shown to induce teratogenesis in both humans and animals. Cocaine-induced teratogenicity has been…”
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