Search Results - "Yu, Shi‐Cang"
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Triple-negative breast cancer molecular subtyping and treatment progress
Published in Breast cancer research : BCR (09-06-2020)“…Abstract Triple-negative breast cancer (TNBC), a specific subtype of breast cancer that does not express estrogen receptor (ER), progesterone receptor (PR), or…”
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Pathological evidence for residual SARS-CoV-2 in pulmonary tissues of a ready-for-discharge patient
Published in Cell research (01-06-2020)Get full text
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ALDH1A3, a metabolic target for cancer diagnosis and therapy
Published in International journal of cancer (01-09-2016)“…Metabolism reprogramming has been linked with the initiation, metastasis, and recurrence of cancer. The aldehyde dehydrogenase (ALDH) family is the most…”
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Beyond a tumor suppressor: Soluble E‐cadherin promotes the progression of cancer
Published in International journal of cancer (15-06-2016)“…E‐cadherin (E‐cad) plays important roles in tumorigenesis as well as in tumor progression, invasion and metastasis. This protein exists in two forms: a…”
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Invasion of white matter tracts by glioma stem cells is regulated by a NOTCH1–SOX2 positive-feedback loop
Published in Nature neuroscience (01-01-2019)“…Early invasive growth along specific anatomical structures, especially the white matter tract, is regarded as one of the main causes of poor therapeutic…”
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CCL8 secreted by tumor-associated macrophages promotes invasion and stemness of glioblastoma cells via ERK1/2 signaling
Published in Laboratory investigation (01-04-2020)“…Tumor-associated macrophages (TAMs) constitute a large population of glioblastoma and facilitate tumor growth and invasion of tumor cells, but the underlying…”
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The role of lysosomes in cancer development and progression
Published in Cell & bioscience (18-11-2020)“…Abstract Lysosomes are an important component of the inner membrane system and participate in numerous cell biological processes, such as macromolecular…”
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ALDEFLUOR activity, ALDH isoforms, and their clinical significance in cancers
Published in Journal of enzyme inhibition and medicinal chemistry (01-12-2023)“…High aldehyde dehydrogenase (ALDH) activity is a metabolic feature of adult stem cells and various cancer stem cells (CSCs). The ALDEFLUOR system is currently…”
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Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth
Published in Nature communications (01-06-2017)“…Intense infiltration of tumour-associated macrophages (TAMs) facilitates malignant growth of glioblastoma (GBM), but the underlying mechanisms remain…”
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Mitochondrial and energy metabolism‐related properties as novel indicators of lung cancer stem cells
Published in International journal of cancer (15-08-2011)“…Energy metabolism is the foundation of survival for all organisms, and mitochondria are the most important energy‐supplying organelles in eukaryotic cells…”
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Glioma invasion along white matter tracts: A dilemma for neurosurgeons
Published in Cancer letters (01-02-2022)“…Invasive growth along white matter (WM) tracts is one of the most prominent clinicopathological features of glioma and is also an important reason for surgical…”
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Metastatic consequences of immune escape from NK cell cytotoxicity by human breast cancer stem cells
Published in Cancer research (Chicago, Ill.) (15-10-2014)“…Breast cancer stem-like cells (BCSC) are crucial for metastasis but the underlying mechanisms remain elusive. Here, we report that tumor-infiltrating natural…”
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Tumor-associated microglia/macrophages enhance the invasion of glioma stem-like cells via TGF-β1 signaling pathway
Published in The Journal of immunology (1950) (01-07-2012)“…The invasion of malignant glioma cells into the surrounding normal brain tissues is crucial for causing the poor outcome of this tumor type. Recent studies…”
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An aldehyde dehydrogenase 1A3 inhibitor attenuates the metastasis of human colorectal cancer
Published in Cancer letters (28-06-2022)“…Metastasis is the leading cause of death for patients with colorectal cancer (CRC). The development of therapeutic regimens that selectively inhibit the…”
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A novel zebrafish xenotransplantation model for study of glioma stem cell invasion
Published in PloS one (16-04-2013)“…Invasion and metastasis of solid tumors are the major causes of death in cancer patients. Cancer stem cells (CSCs) constitute a small fraction of tumor cell…”
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Models for evaluating glioblastoma invasion along white matter tracts
Published in Trends in biotechnology (Regular ed.) (01-03-2024)“…Ideal research models are urgently needed to explore the mechanisms of glioma invasion along white matter tracts (WMs), which is a determinant for the…”
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Spindle apparatus coiled‐coil protein 1 (SPDL1) serves as a novel prognostic biomarker in triple‐negative breast cancer
Published in Proteomics. Clinical applications (01-07-2024)“…Background Triple‐negative breast cancer (TNBC) has a poor prognosis, an ineffective diagnosis, and a high degree of aggressiveness. Therefore, novel…”
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MiR-637 maintains the balance between adipocytes and osteoblasts by directly targeting Osterix
Published in Molecular biology of the cell (01-11-2011)“…Bone development is dynamically regulated by homeostasis, in which a balance between adipocytes and osteoblasts is maintained. Disruption of this…”
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Beyond metabolic waste: lysine lactylation and its potential roles in cancer progression and cell fate determination
Published in Cellular oncology (Dordrecht) (01-06-2023)“…Background Lactate is an important metabolite derived from glycolysis under physiological and pathological conditions. The Warburg effect reveals the vital…”
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The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell-mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling
Published in The Journal of pathology (01-07-2011)“…Chemokines and their receptors are actively involved in inflammation, immune responses, and cancer development. Here we report the detection of CD133+ glioma…”
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