Search Results - "Yu, Shengnan"

Next generation chimeric antigen receptor T cells: safety strategies to overcome toxicity by Yu, Shengnan, Yi, Ming, Qin, Shuang, Wu, Kongming

“…Chimeric antigen receptor T (CAR-T) cell therapy is an emerging and effective cancer immunotherapy. Especially in hematological malignancies, CAR-T cells have…”
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Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4 by Qin, Shuang, Xu, Linping, Yi, Ming, Yu, Shengnan, Wu, Kongming, Luo, Suxia

“…The emergence of immune checkpoint inhibitors (ICIs), mainly including anti-programmed cell death protein 1/programmed cell death ligand 1 (PD-1/PD-L1) and…”
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Advances on immunotherapy for osteosarcoma by Yu, Shengnan, Yao, Xudong

“…Osteosarcoma is the most common primary bone cancer in children and young adults. Limited progress has been made in improving the survival outcomes in patients…”
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EGFR-TKIs resistance via EGFR-independent signaling pathways by Liu, Qian, Yu, Shengnan, Zhao, Weiheng, Qin, Shuang, Chu, Qian, Wu, Kongming

“…Tyrosine kinase inhibitors (TKIs)-treatments bring significant benefit for patients harboring epidermal growth factor receptor (EGFR) mutations, especially for…”
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Recent advances on anti-angiogenesis receptor tyrosine kinase inhibitors in cancer therapy by Qin, Shuang, Li, Anping, Yi, Ming, Yu, Shengnan, Zhang, Mingsheng, Wu, Kongming

“…Angiogenesis has always been the topic of major scientific interest in the field of malignant tumors. Nowadays, targeting angiogenesis has achieved success in…”
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Chimeric antigen receptor T cells: a novel therapy for solid tumors by Yu, Shengnan, Li, Anping, Liu, Qian, Li, Tengfei, Yuan, Xun, Han, Xinwei, Wu, Kongming

“…The chimeric antigen receptor T (CAR-T) cell therapy is a newly developed adoptive antitumor treatment. Theoretically, CAR-T cells can specifically localize…”
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Chondrocyte ferroptosis contribute to the progression of osteoarthritis by Yao, Xudong, Sun, Kai, Yu, Shengnan, Luo, Jiahui, Guo, Jiachao, Lin, Jiamin, Wang, Genchun, Guo, Zhou, Ye, Yaping, Guo, Fengjing

“…Osteoarthritis (OA) is a complex process comprised of mechanical load, inflammation, and metabolic factors. It is still unknown that if chondrocytes undergo…”
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Manipulating TGF-β signaling to optimize immunotherapy for cervical cancer by Yin, Shuping, Cui, Han, Qin, Shuang, Yu, Shengnan

“…Cervical cancer is a serious threat to women's health globally. Therefore, identifying key molecules associated with cervical cancer progression is essential…”
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Gut microbiome modulates efficacy of immune checkpoint inhibitors by Yi, Ming, Yu, Shengnan, Qin, Shuang, Liu, Qian, Xu, Hanxiao, Zhao, Weiheng, Chu, Qian, Wu, Kongming

“…Immune checkpoint inhibitors (ICIs) therapy is a novel strategy for cancer treatments in recent years. However, it was observed that most patients treated with…”
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Smallholder Crop Type Mapping and Rotation Monitoring in Mountainous Areas with Sentinel-1/2 Imagery by Ren, Tingting, Xu, Hongtao, Cai, Xiumin, Yu, Shengnan, Qi, Jiaguo

“…Accurate and timely crop type mapping and rotation monitoring play a critical role in crop yield estimation, soil management, and food supplies. To date, to…”
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Identification and exploration of pharmacological pyroptosis-related biomarkers of ulcerative colitis by Chen, Kaiwei, Shang, Shipeng, Yu, Shengnan, Cui, Luwen, Li, Shangyong, He, Ningning

“…Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD). Its etiology is unclear. Much evidence suggests that the death of abnormal intestinal…”
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Allocate soil individuals to soil classes with topsoil spectral characteristics and decision trees by Zhang, Xiaokang, Liu, Huanjun, Zhang, Xinle, Yu, Shengnan, Dou, Xin, Xie, Yahui, Wang, Nan

“…Spectral reflectance of soil is a function of physical and chemical characteristics and its internal structure. Spectral reflectance provides a novel approach…”
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Recent advances of highly selective CDK4/6 inhibitors in breast cancer by Xu, Hanxiao, Yu, Shengnan, Liu, Qian, Yuan, Xun, Mani, Sridhar, Pestell, Richard G, Wu, Kongming

“…Uncontrolled cell division is the hallmark of cancers. Full understanding of cell cycle regulation would contribute to promising cancer therapies. In…”
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Recent advances of bispecific antibodies in solid tumors by Yu, Shengnan, Li, Anping, Liu, Qian, Yuan, Xun, Xu, Hanxiao, Jiao, Dechao, Pestell, Richard G, Han, Xinwei, Wu, Kongming

“…Cancer immunotherapy is the most exciting advancement in cancer therapy. Similar to immune checkpoint blockade and chimeric antigen receptor T cell (CAR-T),…”
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The role of neoantigen in immune checkpoint blockade therapy by Yi, Ming, Qin, Shuang, Zhao, Weiheng, Yu, Shengnan, Chu, Qian, Wu, Kongming

“…Immune checkpoint inhibitor induces tumor rejection by activated host immune system. The anti-tumor immune response consists of capture, presentation,…”
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High permeability hydrogel membranes of chitosan/poly ether-block-amide blends for CO2 separation by Liu, Ye, Yu, Shengnan, Wu, Hong, Li, Yifan, Wang, Shaofei, Tian, Zhizhang, Jiang, Zhongyi

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Fabrication of bilayer Pd-Pt nanocages with sub-nanometer thin shells for enhanced hydrogen evolution reaction by Wang, Yihe, Zhang, Lei, Hu, Congling, Yu, Shengnan, Yang, Piaoping, Cheng, Dongfang, Zhao, Zhi-Jian, Gong, Jinlong

“…The hydrogen evolution reaction (HER), which generates molecular hydrogen through the electrochemical reduction of water, is an important clean-energy…”
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A novel asymmetrical anti-HER2/CD3 bispecific antibody exhibits potent cytotoxicity for HER2-positive tumor cells by Yu, Shengnan, Zhang, Jing, Yan, Yongxiang, Yao, Xudong, Fang, Lijuan, Xiong, Hui, Liu, Yang, Chu, Qian, Zhou, Pengfei, Wu, Kongming

“…Human epidermal growth factor receptor 2 (HER2) is overexpressed in multiple cancers, which is associated with poor prognosis. Herceptin and other agents…”
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PTEN inhibitor VO-OHpic attenuates GC-associated endothelial progenitor cell dysfunction and osteonecrosis of the femoral head via activating Nrf2 signaling and inhibiting mitochondrial apoptosis pathway by Yao, Xudong, Yu, Shengnan, Jing, Xingzhi, Guo, Jiachao, Sun, Kai, Guo, Fengjing, Ye, Yaping

“…Glucocorticoid (GC)-associated osteonecrosis of the femoral head (ONFH) is the most common in non-traumatic ONFH. Despite a strong relationship between GC and…”
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DACH1 antagonizes CXCL8 to repress tumorigenesis of lung adenocarcinoma and improve prognosis by Liu, Qian, Li, Anping, Yu, Shengnan, Qin, Shuang, Han, Na, Pestell, Richard G, Han, Xinwei, Wu, Kongming

“…C-X-C motif ligand 8 (CXCL8), known as a proinflammatory chemokine, exerts multiple effects on the proliferation, invasion, and migration of tumor cells via…”
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