Search Results - "Yu, Myounghee"
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Endoplasmic reticulum calcium pool depletion-induced apoptosis is coupled with activation of the death receptor 5 pathway
Published in Oncogene (18-04-2002)“…Thapsigargin (TG), by inducing perturbations in cellular Ca(2+) homeostasis, has been shown to induce apoptosis. The molecular mechanisms of Ca(2+)…”
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Specific Substitutions at Amino Acid 256 of the Sarcoplasmic/Endoplasmic Reticulum Ca2+ Transport ATPase Mediate Resistance to Thapsigargin in Thapsigargin-resistant Hamster Cells
Published in The Journal of biological chemistry (06-02-1998)“…High levels of resistance to thapsigargin (TG), a specific inhibitor of intracellular Ca 2+ transport ATPases (SERCAs), can be developed in culture by stepwise…”
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Cloning and Characterization of a Human Genotoxic and Endoplasmic Reticulum Stress-inducible cDNA That Encodes Translation Initiation Factor 1(eIF1A121/SUI1)
Published in The Journal of biological chemistry (04-06-1999)“…We report the cloning and characterization of a DNA damage-inducible (DDI) transcript DDI A121. The full-length human DDI A121 cDNA contains an open reading…”
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Allelic variation in the dihydrofolate reductase gene at amino acid position 95 contributes to antifolate resistance in chinese hamster cells
Published in Cancer research (Chicago, Ill.) (15-12-1993)“…The Chinese hamster lung cell line DC-3F contains two polymorphic dihydrofolate reductase (DHFR) alleles that are defined by an Asp-Asn amino acid sequence…”
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Effects of Various Amino Acid 256 Mutations on Sarcoplasmic/Endoplasmic Reticulum Ca2+ATPase Function and Their Role in the Cellular Adaptive Response to Thapsigargin
Published in Archives of biochemistry and biophysics (15-02-1999)“…Upon direct selection of mammalian cells for resistance to thapsigargin (TG), a potent inhibitor of the sarcoplasmic/endoplasmic reticulum Ca2+transport ATPase…”
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Specific substitutions at amino acid 256 of the sarcoplasmic/endoplasmic reticulum Ca super(2+) transport ATPase mediate resistance to thapsigargin in thapsigargin-resistant hamster cells
Published in The Journal of biological chemistry (01-02-1998)“…High levels of resistance to thapsigargin (TG), a specific inhibitor of intracellular Ca super(2+) transport ATPases (SERCAs), can be developed in culture by…”
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Gene amplification and transcriptional upregulation of the sarco/endoplasmic reticulum Ca2+ transport ATPase in thapsigargin-resistant hamster smooth muscle cells
Published in Nucleic acids research (01-10-1998)“…We have selected a series of cell lines from the parental Syrian hamster smooth muscle cell line DDT1-MF2 that are resistant to thapsigargin (TG), a specific…”
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Calcium Entry into the Inositol 1,4,5-trisphosphate-Releasable Calcium Pool is Mediated by a GTP-Regulatory Mechanism
Published in Proceedings of the National Academy of Sciences - PNAS (01-04-1988)“…Intracellular Ca2+ release activated by inositol 1,4,5-trisphosphate (InsP3) plays a pivotal role in Ca2+ signaling in cells. A controlling mechanism for…”
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Construction of a dominant selectable marker using a novel dihydrofolate reductase
Published in Gene (15-03-1992)“…Simian virus 40 promoter-enhancer-based mammalian expression plasmids using dihydrofolate reductase (DHFR)-encoding cDNA sequences originally isolated from two…”
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