Search Results - "Yu, Lexing"
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Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer
Published in Nature communications (15-01-2018)“…The communication between tumor-derived elements and stroma in the metastatic niche has a critical role in facilitating cancer metastasis. Yet, the mechanisms…”
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The Roles of Neutrophils in the Pathogenesis of Liver Diseases
Published in Frontiers in immunology (08-03-2021)“…Neutrophils are the largest population of circulating leukocytes and the first responder against invading pathogens or other danger signals. Sophisticated…”
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Prognostic Significance of AMPK Activation and Therapeutic Effects of Metformin in Hepatocellular Carcinoma
Published in Clinical cancer research (01-10-2013)“…The AMP-activated protein kinase (AMPK) serves as an energy sensor in eukaryotic cells and occupies a central role in linking metabolism and cancer…”
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MicroRNA‐21 and Dicer are dispensable for hepatic stellate cell activation and the development of liver fibrosis
Published in Hepatology (Baltimore, Md.) (01-06-2018)“…Fibrosis and cancer represent two major complications of chronic liver disease. MicroRNAs have been implicated in the development of fibrosis and cancer, thus…”
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Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations
Published in Cancer cell (14-06-2021)“…Cancer-associated fibroblasts (CAF) are a poorly characterized cell population in the context of liver cancer. Our study investigates CAF functions in…”
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Interleukin‐1β/Iinterleukin‐1 receptor‐associated kinase 1 inflammatory signaling contributes to persistent Gankyrin activation during hepatocarcinogenesis
Published in Hepatology (Baltimore, Md.) (01-02-2015)“…Hepatocellular carcinoma (HCC) is a prototype of inflammation‐associated cancer. Oncoprotein Gankyrin, which mostly increases in HCC, plays a critical role in…”
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Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations
Published in Cancer cell (14-06-2021)Get full text
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8
Interleukin-1[beta]/Iinterleukin-1 receptor-associated kinase 1 inflammatory signaling contributes to persistent Gankyrin activation during hepatocarcinogenesis
Published in Hepatology (Baltimore, Md.) (01-02-2015)“…Hepatocellular carcinoma (HCC) is a prototype of inflammation-associated cancer. Oncoprotein Gankyrin, which mostly increases in HCC, plays a critical role in…”
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Disturbance of Ca2+ Homeostasis Converts Pro-Met into Non-canonical Tyrosine Kinase p190MetNC in Response to Endoplasmic Reticulum Stress in MHCC97 Cells
Published in The Journal of biological chemistry (27-04-2012)“…c-Met, the tyrosine-kinase receptor for hepatocyte growth factor, plays a critical role in the tumorigenesis of hepatocellular carcinoma (HCC). However, the…”
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