Search Results - "Yu, Jau‐Song"

Macrophage achieves self-protection against oxidative stress-induced ageing through the Mst-Nrf2 axis by Wang, Ping, Geng, Jing, Gao, Jiahui, Zhao, Hao, Li, Junhong, Shi, Yiran, Yang, Bingying, Xiao, Chen, Linghu, Yueyue, Sun, Xiufeng, Chen, Xin, Hong, Lixin, Qin, Funiu, Li, Xun, Yu, Jau-Song, You, Han, Yuan, Zengqiang, Zhou, Dawang, Johnson, Randy L., Chen, Lanfen

“…Reactive oxygen species (ROS) production in phagocytes is a major defense mechanism against pathogens. However, the cellular self-protective mechanism against…”
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JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1α–mediated glucose metabolism by Wang, Hung-Jung, Hsieh, Ya-Ju, Cheng, Wen-Chi, Lin, Chun-Pu, Lin, Yu-shan, Yang, So-Fang, Chen, Chung-Ching, Izumiya, Yoshihiro, Yu, Jau-Song, Kung, Hsing-Jien, Wang, Wen-Ching

“…JMJD5, a Jumonji C domain-containing dioxygenase, is important for embryonic development and cancer growth. Here, we show that JMJD5 is up-regulated by hypoxia…”
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APOBEC3A is an oral cancer prognostic biomarker in Taiwanese carriers of an APOBEC deletion polymorphism by Chen, Ting-Wen, Lee, Chi-Ching, Liu, Hsuan, Wu, Chi-Sheng, Pickering, Curtis R., Huang, Po-Jung, Wang, Jing, Chang, Ian Yi-Feng, Yeh, Yuan-Ming, Chen, Chih-De, Li, Hsin-Pai, Luo, Ji-Dung, Tan, Bertrand Chin-Ming, Chan, Timothy En Haw, Hsueh, Chuen, Chu, Lichieh Julie, Chen, Yi-Ting, Zhang, Bing, Yang, Chia-Yu, Wu, Chih-Ching, Hsu, Chia-Wei, See, Lai-Chu, Tang, Petrus, Yu, Jau-Song, Liao, Wei-Chao, Chiang, Wei-Fan, Rodriguez, Henry, Myers, Jeffrey N., Chang, Kai-Ping, Chang, Yu-Sun

“…Oral squamous cell carcinoma is a prominent cancer worldwide, particularly in Taiwan. By integrating omics analyses in 50 matched samples, we uncover in…”
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Specific long‐term changes in anti‐SARS‐CoV‐2 IgG modifications and antibody functions in mRNA, adenovector, and protein subunit vaccines by Reinig, Sebastian, Kuo, Chin, Wu, Chia‐Chun, Huang, Sheng‐Yu, Yu, Jau‐Song, Shih, Shin‐Ru

“…Various vaccine platforms were developed and deployed against the COVID‐19 disease. The Fc‐mediated functions of IgG antibodies are essential in the adaptive…”
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DDX3 interacts with USP9X and participates in deubiquitination of the anti‐apoptotic protein MCL1 by Lai, Ming‐Chih, Chen, Yi‐Pin, Li, Ding‐An, Yu, Jau‐Song, Hung, Hsin‐Yuan, Tarn, Woan‐Yuh

“…Here, we describe a novel interaction between the RNA helicase DDX3 and the deubiquitinase ubiquitin‐specific peptidase 9 X‐linked (USP9X) in human cells…”
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ABCG2 Mediates Resistance to the Dual EGFR and PI3K Inhibitor MTX-211 in Cancer Cells by Wu, Chung-Pu, Hung, Cheng-Yu, Murakami, Megumi, Wu, Yu-Shan, Chu, Yi-Hsuan, Huang, Yang-Hui, Yu, Jau-Song, Ambudkar, Suresh V

“…MTX-211 is a first-in-class dual inhibitor of epidermal growth factor receptor (EGFR) and phosphoinositide-3 kinase (PI3K) signaling pathways with a compelling…”
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Graphene Oxide and Fluorescent-Aptamer-Based Novel Aptasensors for Detection of Metastatic Colorectal Cancer Cells by Chen, Hang, Zhang, Shurui, Hsiao, Yung-Chin, Wang, Qun, Yu, Jau-Song, Li, Wanming

“…Early diagnosis of metastatic colorectal cancer (mCRC) is extremely critical to improve treatment and extend survival. W3 is an aptamer that can specifically…”
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From discovery of tyrosine phosphorylation to targeted cancer therapies: The 2018 Tang Prize in Biopharmaceutical Science by Yu, Jau-Song

“…Protein tyrosine kinases (TKs) are a family of enzymes that catalyze the phosphorylation of proteins at tyrosine residues. TKs play key roles in controlling…”
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Development of sandwich ELISA and lateral flow strip assays for diagnosing clinically significant snakebite in Taiwan by Liu, Chien-Chun, Yu, Jau-Song, Wang, Po-Jung, Hsiao, Yung-Chin, Liu, Chien-Hsin, Chen, Yen-Chia, Lai, Pei-Fang, Hsu, Chih-Po, Fann, Wen-Chih, Lin, Chih-Chuan

“…Taiwan is an island located in the south Pacific, a subtropical region that is home to 61 species of snakes. Of these snakes, four species-Trimeresurus…”
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Identification of Endothelial Cell Protein C Receptor by Urinary Proteomics as Novel Prognostic Marker in Non-Recovery Kidney Injury by Chang, Chih-Hsiang, Lee, Cheng-Chia, Chen, Yung-Chang, Fan, Pei-Chun, Chu, Pao-Hsien, Chu, Lichieh Julie, Yu, Jau-Song, Chen, Hsiao-Wei, Yang, Chih-Wei, Chen, Yi-Ting

“…Acute kidney injury is a common and complex complication that has high morality and the risk for chronic kidney disease among survivors. The accuracy of…”
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Saliva protein biomarkers to detect oral squamous cell carcinoma in a high-risk population in Taiwan by Yu, Jau-Song, Chen, Yi-Ting, Chiang, Wei-Fan, Hsiao, Yung-Chin, Chu, Lichieh Julie, See, Lai-Chu, Wu, Chi-Sheng, Tu, Hui-Tzu, Chen, Hsiao-Wei, Chen, Chia-Chun, Liao, Wei-Chao, Chang, Ya-Ting, Wu, Chih-Ching, Lin, Che-Yi, Liu, Shyun-Yeu, Chiou, Shu-Ti, Chia, Shu-Li, Chang, Kai-Ping, Chien, Chih-Yen, Chang, Su-Wei, Chang, Chee-Jen, Young, John D., Pao, Chia C., Chang, Yu-Sun, Hartwell, Leland H.

“…Most cases of oral squamous cell carcinoma (OSCC) develop from visible oral potentially malignant disorders (OPMDs). The latter exhibit heterogeneous subtypes…”
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Analysis of the efficacy of Taiwanese freeze-dried neurotoxic antivenom against Naja kaouthia, Naja siamensis and Ophiophagus hannah through proteomics and animal model approaches by Liu, Chien-Chun, You, Chen-Hsien, Wang, Po-Jung, Yu, Jau-Song, Huang, Guo-Jen, Liu, Chien-Hsin, Hsieh, Wen-Chin, Lin, Chih-Chuan

“…In Southeast Asia, envenoming resulting from cobra snakebites is an important public health issue in many regions, and antivenom therapy is the standard…”
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Pathogenesis of local necrosis induced by Naja atra venom: Assessment of the neutralization ability of Taiwanese freeze-dried neurotoxic antivenom in animal models by Liu, Chien-Chun, Chou, Yu-Shao, Chen, Chun-Yu, Liu, Kuei-Lin, Huang, Guo-Jen, Yu, Jau-Song, Wu, Cho-Ju, Liaw, Geng-Wang, Hsieh, Cheng-Hsien, Chen, Chun-Kuei

“…Naja atra envenomation is one of the most significant clinical snakebite concerns in Taiwan. Taiwanese freeze-dried neurotoxic antivenom (FNAV) is currently…”
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Importin subunit alpha‐2 is identified as a potential biomarker for non‐small cell lung cancer by integration of the cancer cell secretome and tissue transcriptome by Wang, Chun‐I., Wang, Chih‐Liang, Wang, Chih‐Wei, Chen, Chi‐De, Wu, Chih‐Ching, Liang, Ying, Tsai, Ying‐Huang, Chang, Yu‐Sun, Yu, Jau‐Song, Yu, Chia‐Jung

“…The cancer cell secretome may contain potentially useful biomarkers. In this study, we integrated the profiles of secreted proteins in lung cancer cell lines…”
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Identification of Fucosylated SERPINA1 as a Novel Plasma Marker for Pancreatic Cancer Using Lectin Affinity Capture Coupled with iTRAQ-Based Quantitative Glycoproteomics by Wu, Chia-Chun, Lu, Yu-Ting, Yeh, Ta-Sen, Chan, Yun-Hsin, Dash, Srinivas, Yu, Jau-Song

“…Pancreatic cancer (PC) is an aggressive cancer with a high mortality rate, necessitating the development of effective diagnostic, prognostic and predictive…”
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An immuno-MALDI mass spectrometry assay for the oral cancer biomarker, matrix metalloproteinase-1, in dried saliva spot samples by Hsiao, Yung-Chin, Lin, Shih-Yu, Chien, Kun-Yi, Chen, Szu-Fan, Wu, Chia-Chun, Chang, Ya-Ting, Chi, Lang-Ming, Chu, Lichieh Julie, Chiang, Wei-Fan, Chien, Chih-Yen, Chang, Kai-Ping, Chang, Yu-Sun, Yu, Jau-Song

“…Oral cavity cancer is a common cancer type that presents an increasingly serious global problem. Oral squamous cell carcinoma (OSCC) accounts for >90% oral…”
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Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis by Chung, I-Che, OuYang, Chun-Nan, Yuan, Sheng-Ning, Li, Hsin-Pai, Chen, Jeng-Ting, Shieh, Hui-Ru, Chen, Yu-Jen, Ojcius, David M., Chu, Ching-Liang, Yu, Jau-Song, Chang, Yu-Sun, Chen, Lih-Chyang

“…The inflammasome adaptor protein, ASC, contributes to both innate immune responses and inflammatory diseases via self-oligomerization, which leads to the…”
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Association of urinary ketamine and APOA1 levels with bladder dysfunction in ketamine abusers revealed via proteomics and targeted metabolite analyses by Liu, Jo-Chuan, Chen, Yi-Ting, Hsieh, Ya-Ju, Wu, Chia-Chun, Huang, Ming-Chyi, Hsu, Yu-Chao, Wu, Chun-Te, Chen, Chih-Ken, Dash, Srinivas, Yu, Jau-Song

“…Chronic ketamine abuse is associated with bladder dysfunction and cystitis. However, the effects of ketamine abuse on the urinary proteome profile and the…”
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The Clinical Usefulness of Taiwan Bivalent Freeze-Dried Hemorrhagic Antivenom in Protobothrops mucrosquamatus - and Viridovipera stejnegeri -Envenomed Patients by Lin, Chih-Chuan, Shih, Chia-Pang, Wang, Chia-Cheng, Ouyang, Chun-Hsiang, Liu, Chien-Chun, Yu, Jau-Song, Lo, Chih-Hong

“…Snakebites from (Taiwan habus) and (green bamboo vipers) account for the most venomous snakebites in Taiwan. The bivalent freeze-dried hemorrhagic (FH)…”
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TACCO, a Database Connecting Transcriptome Alterations, Pathway Alterations and Clinical Outcomes in Cancers by Chou, Po-Hao, Liao, Wei-Chao, Tsai, Kuo-Wang, Chen, Ku-Chung, Yu, Jau-Song, Chen, Ting-Wen

“…Because of innumerable cancer sequencing projects, abundant transcriptome expression profiles together with survival data are available from the same patients…”
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