Search Results - "Yu, Jack X"

Novel Genes Associated with Malignant Melanoma but not Benign Melanocytic Lesions by Talantov, Dmitri, Mazumder, Abhijit, Yu, Jack X, Briggs, Thomas, Jiang, Yuqiu, Backus, John, Atkins, David, Wang, Yixin

“…Purpose: Cutaneous melanoma is a common, aggressive cancer with increasing incidence. The identification of melanoma-specific deregulated genes could provide…”
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Pathway analysis of gene signatures predicting metastasis of node-negative primary breast cancer by Yu, Jack X, Sieuwerts, Anieta M, Zhang, Yi, Martens, John W M, Smid, Marcel, Klijn, Jan G M, Wang, Yixin, Foekens, John A

“…Published prognostic gene signatures in breast cancer have few genes in common. Here we provide a rationale for this observation by studying the prognostic…”
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mRNA and microRNA Expression Profiles in Circulating Tumor Cells and Primary Tumors of Metastatic Breast Cancer Patients by SIEUWERTS, Anieta M, MOSTERT, Bianca, KRAAN, Jaco, VAN DER SPOEL, Petra, RAMIREZ-MORENO, Raquel, VAN DEURZEN, Carolien H. M, SMID, Marcel, YU, Jack X, JIANG, John, YIXIN WANG, GRATAMA, Jan W, SLEIJFER, Stefan, BOLT-DE VRIES, Joan, FOEKENS, John A, MARTENS, John W. M, PEETERS, Dieter, DE JONGH, Felix E, STOUTHARD, Jacqueline M. L, DIRIX, Luc Y, VAN DAM, Peter A, VAN GALEN, Anne, DE WEERD, Vanja

“…Molecular characterization of circulating tumor cells (CTC) holds great promise. Unfortunately, routinely isolated CTC fractions currently still contain…”
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Copy Number Alterations that Predict Metastatic Capability of Human Breast Cancer by YI ZHANG, MARTENS, John W. M, YU, Jack X, JIANG, John, SIEUWERTS, Anieta M, SMID, Marcel, KLIJN, Jan G. M, YIXIN WANG, FOEKENS, John A

“…We have analyzed the DNA copy numbers for over 100,000 single-nucleotide polymorphism loci across the human genome in genomic DNA from 313 lymph node-negative…”
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RIZ1, but not the alternative RIZ2 product of the same gene, is underexpressed in breast cancer, and forced RIZ1 expression causes G2-M cell cycle arrest and/or apoptosis by LIUSHENG HE, YU, J. X, LIMIN LIU, BUYSE, I. M, WANG, M.-S, YANG, Q.-C, NAKAGAWARA, A, BRODEUR, G. M, SHI, Y. E, SHI HUANG

“…The retinoblastoma protein-interacting zinc finger gene RIZ maps to the distal short arm of human chromosome 1 (1p36), a region thought to harbor tumor…”
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Molecular Cloning, Tissue-specific Expression, and Cellular Localization of Human Prostasin mRNA by Yu, Jack X., Chao, Lee, Chao, Julie

“…We have purified a novel human serine proteinase, designated as prostasin, from seminal fluid (Yu et al., 1994). In the present study, we have cloned and…”
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Constitutive expression of proinflammatory complement components by subsets of neurons in the central nervous system by Yu, Jack X, Bradt, Bonnie M, Cooper, Neil R

“…The brain is largely protected from damage due to infection, trauma, and aberrant processes by the innate immune system. These studies were undertaken to…”
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Focal inflammation in the brain: role in Alzheimer's disease by Cooper, N R, Bradt, B M, O'Barr, S, Yu, J X

“…We hypothesize that amyloid (Abeta) peptide-containing neuritic plaques in the brains of patients with Alzheimer's disease represent chronic inflammatory foci…”
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Structure and Chromosomal Localization of the Human Prostasin (PRSS8) Gene by Yu, Jack X., Chao, Lee, Ward, David C., Chao, Julie

“…Prostasin, denoted as PRSS8, is a newly identified human serine proteinase that shares high sequence identity with acrosin, plasma kallikrein, and hepsin (Yuet…”
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Prostasin is a novel human serine proteinase from seminal fluid. Purification, tissue distribution, and localization in prostate gland by YU, J. X, LEE CHAO, CHAO, L

“…A novel serine proteinase, designated as prostasin, has been purified from human seminal fluid to apparent homogeneity by DEAE-Sepharose CL-6B and…”
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Molecular cloning of the C6A form cDNA of the mouse sixth complement component: functional integrity despite the absence of factor I modules by Yu, J X, Bradt, B M, Cooper, N R

“…The sixth complement component (C6) is an essential component of the biologically active C5b-9 membrane attack complex of the complement system. The…”
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