Search Results - "Yu, Huanling"
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Gut microbiota–derived metabolite trimethylamine-N-oxide and multiple health outcomes: an umbrella review and updated meta-analysis
Published in The American journal of clinical nutrition (01-07-2022)“…Trimethylamine-N-oxide (TMAO) is a gut microbiota–derived metabolite produced from dietary nutrients. Many studies have discovered that circulating TMAO…”
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Genistein antagonizes inflammatory damage induced by β-amyloid peptide in microglia through TLR4 and NF-κB
Published in Nutrition (Burbank, Los Angeles County, Calif.) (2014)“…Abstract Objectives Microglia activation and neuroinflammation have been associated with the pathogenesis of neurodegenerative disorders such as Alzheimer’s…”
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Weekly-specific ambient PM1 before and during pregnancy and the risk of gestational diabetes mellitus
Published in Ecotoxicology and environmental safety (01-10-2024)“…Exposure to fine or respirable particulate matter has been linked to an elevated risk of gestational diabetes mellitus (GDM). However, the association between…”
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Nuclear Binding Protein 2/Nesfatin-1 Affects Trophoblast Cell Fusion during Placental Development via the EGFR-PLCG1-CAMK4 Pathway
Published in International journal of molecular sciences (01-02-2024)“…Previous studies have shown that nuclear binding protein 2 ( ) is expressed in the human placenta and increases with an increase in the syncytialization of…”
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High serum triglyceride levels in the early first trimester of pregnancy are associated with gestational diabetes mellitus: A prospective cohort study
Published in Journal of diabetes investigation (01-11-2020)“…Aims/Introduction Pregnant women with gestational diabetes mellitus (GDM) have been reported to have higher serum triglyceride (TG) levels during the entire…”
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Association between Exposure to the Chinese Famine in Different Stages of Early Life and Decline in Cognitive Functioning in Adulthood
Published in Frontiers in behavioral neuroscience (14-07-2016)“…To investigate whether exposure to the Chinese Famine in different life stages of early life is associated with cognitive functioning decline in adulthood. We…”
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Lipid-focused dietary education intervention in pregnant women: study protocol for an open-label, parallel, randomised, intervention study addressing adverse pregnancy outcomes in China
Published in BMJ open (04-01-2024)“…IntroductionThe incidence of infants who are large-for-gestational-age (LGA) is on the rise in China, and its detrimental effects on health have received…”
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Oat nutritious meal has beneficial effect on lipid metabolism in type 2 diabetes mellitus: A 3-month randomized controlled trial
Published in Journal of functional foods (01-08-2022)“…[Display omitted] •ONM has beneficial effects on lipid metabolism in elderly patients with T2DM.•ONM intervention led to the reduction in TC and LDL-c levels…”
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Assessment of evidence on reported non-genetic risk factors of congenital heart defects: the updated umbrella review
Published in BMC pregnancy and childbirth (29-04-2022)“…Congenital heart defect (CHD) is the leading cause of birth defects globally, which results in a great disease burden. It is still imperative to detect the…”
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Changes in serum TG levels during pregnancy and their association with postpartum hypertriglyceridemia: a population-based prospective cohort study
Published in Lipids in health and disease (29-09-2021)“…Blood lipid increases during gestation are considered a physiological adaption, and decrease after delivery. However, some adverse pregnancy outcomes are…”
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Associations between maternal serum HDL-c concentrations during pregnancy and neonatal birth weight: a population-based cohort study
Published in Lipids in health and disease (14-05-2020)“…To evaluate the associations between maternal serum concentrations of high-density lipoprotein cholesterol (HDL-c) throughout pregnancy and neonatal birth…”
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The Effects of 5,6,7,8,3',4'-Hexamethoxyflavone on Apoptosis of Cultured Human Choriocarcinoma Trophoblast Cells
Published in Molecules (Basel, Switzerland) (20-02-2020)“…5,6,7,8,3,4'-Hexamethoxyflavone, also called nobiletin (NOB), widely found in the citrus peel, is one of the main byproducts in citrus processing. NOB is…”
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Nobiletin, a hexamethoxyflavonoid from citrus pomace, attenuates G1 cell cycle arrest and apoptosis in hypoxia-induced human trophoblast cells of JEG-3 and BeWo via regulating the p53 signaling pathway
Published in Food & nutrition research (24-09-2021)“…Hypoxia is associated with abnormal cell apoptosis in trophoblast cells, which causes fetal growth restriction and related placental pathologies. Few effective…”
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Prenatal Choline Supplementation during High-Fat Feeding Improves Long-Term Blood Glucose Control in Male Mouse Offspring
Published in Nutrients (04-01-2020)“…Maternal obesity increases the risk of metabolic dysregulation in rodent offspring, especially when offspring are exposed to a high-fat (HF), obesogenic diet…”
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Association of maternal HDL2-c concentration in the first trimester and the risk of large for gestational age birth
Published in Lipids in health and disease (15-08-2022)“…Abstract Background Maternal lipid levels during pregnancy are critical for fetal development. Recent studies revealed that high-density lipoprotein…”
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Genistein alleviates β-amyloid-induced inflammatory damage through regulating Toll-like receptor 4/nuclear factor κB
Published in Journal of medicinal food (01-03-2015)“…Genistein (GEN), a major soybean isoflavone (SIF), might possess neuroprotective properties through its anti-inflammatory activity. We hypothesized that GEN…”
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The high maternal TG level at early trimester was associated with the increased risk of LGA newborn in non-obesity pregnant women
Published in Lipids in health and disease (26-12-2018)“…Recent research had shown blood glucose was not the only cause of large for gestational age infant (LGA), the contributions of other fuels such as lipids also…”
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Long‐term effects of high lipid and high energy diet on serum lipid, brain fatty acid composition, and memory and learning ability in mice
Published in International journal of developmental neuroscience (01-05-2010)“…Objective It is well known that high lipid and high energy diet is harmful to health. But the different effects of high lipid diet composed of either saturated…”
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The challenge and opportunity of gut microbiota‐targeted nanomedicine for colorectal cancer therapy
Published in iMeta (01-08-2024)“…The gut microbiota is an integral component of the colorectal cancer (CRC) microenvironment and is intimately associated with CRC initiation, progression, and…”
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Health effects of high serum calcium levels: Updated phenome-wide Mendelian randomisation investigation and review of Mendelian randomisation studies
Published in EBioMedicine (01-02-2022)“…Calcium plays a role in a wide range of biological functions. Here we conducted a phenome-wide Mendelian randomisation (MR-PheWAS) analysis and a systematic…”
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