Search Results - "Yu, Henry N"

Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor by Jiang, Xuliang, Liu, Heli, Chen, Xiaoyan, Chen, Po-Han, Fischer, David, Sriraman, Venkataraman, Yu, Henry N, Arkinstall, Steve, He, Xiaolin

“…FSH, a glycoprotein hormone, and the FSH receptor (FSHR), a G protein-coupled receptor, play central roles in human reproduction. We report the crystal…”
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Discovery and Development of Small Molecule Allosteric Modulators of Glycoprotein Hormone Receptors by Nataraja, Selvaraj G, Yu, Henry N, Palmer, Stephen S

“…Glycoprotein hormones, follicle-stimulating hormone (FSH), luteinizing hormone (LH), and thyroid-stimulating hormone (TSH) are heterodimeric proteins with a…”
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Pharmacological Programming of Endosomal Signaling Activated by Small Molecule Ligands of the Follicle Stimulating Hormone Receptor by Sposini, Silvia, De Pascali, Francesco, Richardson, Rachel, Sayers, Niamh S, Perrais, David, Yu, Henry N, Palmer, Stephen, Nataraja, Selva, Reiter, Eric, Hanyaloglu, Aylin C

“…Follicle-stimulating hormone receptor (FSHR) is a G protein-coupled receptor (GPCR) with pivotal roles in reproduction. One key mechanism dictating the signal…”
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Pharmacological Characterization of Low Molecular Weight Biased Agonists at the Follicle Stimulating Hormone Receptor by De Pascali, Francesco, Ayoub, Mohammed Akli, Benevelli, Riccardo, Sposini, Silvia, Lehoux, Jordan, Gallay, Nathalie, Raynaud, Pauline, Landomiel, Flavie, Jean-Alphonse, Frédéric, Gauthier, Christophe, Pellissier, Lucie P., Crépieux, Pascale, Poupon, Anne, Inoue, Asuka, Joubert, Nicolas, Viaud-Massuard, Marie-Claude, Casarini, Livio, Simoni, Manuela, Hanyaloglu, Aylin C., Nataraja, Selva G., Yu, Henry N., Palmer, Stephen S., Yvinec, Romain, Reiter, Eric

“…Follicle-stimulating hormone receptor (FSHR) plays a key role in reproduction through the activation of multiple signaling pathways. Low molecular weight (LMW)…”
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Follicle-Stimulating Hormone Induces Lipid Droplets via Gαi/o and β-Arrestin in an Endometrial Cancer Cell Line by Sayers, Niamh S, Anujan, Priyanka, Yu, Henry N, Palmer, Stephen S, Nautiyal, Jaya, Franks, Stephen, Hanyaloglu, Aylin C

“…Follicle-stimulating hormone (FSH) and its G protein-coupled receptor, FSHR, represents a paradigm for receptor signaling systems that activate multiple and…”
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Thiooligosaccharide Conjugate Vaccines Evoke Antibodies Specific for Native Antigens by Bundle, David R., Rich, Jamie R., Jacques, Sandra, Yu, Henry N., Nitz, Mark, Ling, Chang-Chun

“…When S is SO much better: Conjugate vaccines that contain S‐glycosides induce carbohydrate‐specific antibodies that cross react with the corresponding…”
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Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer by Jiang, Xuliang, Fischer, David, Chen, Xiaoyan, McKenna, Sean D., Liu, Heli, Sriraman, Venkataraman, Yu, Henry N., Goutopoulos, Andreas, Arkinstall, Steve, He, Xiaolin

“…Follicle-stimulating hormone receptor (FSHR), a G-protein coupled receptor, is an important drug target in the development of novel therapeutics for…”
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Rescue of Cell Surface Expression and Signaling of Mutant Follicle-Stimulating Hormone Receptors by Hanyroup, Sharika, Anderson, Ross C, Nataraja, Selvaraj, Yu, Henry N, Millar, Robert P, Newton, Claire L

“…Mutations in G protein-coupled receptors (GPCRs) underlie numerous diseases. Many cause receptor misfolding and failure to reach the cell surface…”
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Discovery of substituted benzamides as follicle stimulating hormone receptor allosteric modulators by Yu, Henry N., Richardson, Thomas E., Nataraja, Selva, Fischer, David J., Sriraman, Venkataraman, Jiang, Xuliang, Bharathi, Pandi, Foglesong, Robert J., Haxell, Thomas F.N., Heasley, Brian H., Jenks, Mathew, Li, Jane, Dugas, Melanie S., Collis, Regina, Tian, Hui, Palmer, Stephen, Goutopoulos, Andreas

“…Follicle-stimulating hormone (FSH), acting on its receptor (FSHR), plays a pivotal role in the stimulation of follicular development and maturation. Multiple…”
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A General Strategy toward S-Linked Glycopeptides by Thayer, Desiree A., Yu, Henry N., Galan, M. Carmen, Wong, Chi-Huey

“…A high‐yield one‐pot synthesis of S‐linked glycosyl amino acids 1 has been developed (see scheme; DMF=dimethyl formamide) and used in the solid‐phase synthesis…”
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Novel Efficient Routes to Heparin Monosaccharides and Disaccharides Achieved via Regio- and Stereoselective Glycosidation by Yu, Henry N, Furukawa, Jun-ichi, Ikeda, Tsuyoshi, Wong, Chi-Huey

“…A new methodology for the synthesis of heparin building blocks has been developed. We describe novel efficient routes to both l-iduronic acid and d-glucuronic…”
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OR03-01 Functional Rescue Of Trafficking-Defective Mutant Follicle-Stimulating Hormone Receptors (FSHR) Leading To Premature Ovarian Failure With The Pharmacoperone CAN1405 by Ulloa-Aguirre, Alfredo, Zariñán, Teresa, Gutiérrez-Sagal, Rubén, Nataraja, Selvaraj, Yu, Henry N, Jardón-Valadez, Eduardo

“…Abstract Disclosure: A. Ulloa-Aguirre: None. T. Zariñán: None. R. Gutiérrez-Sagal: None. S. Nataraja: None. H.N. Yu: None. E. Jardón-Valadez: None…”
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Synthesis of three Salmonella epitopes for biosensor studies of carbohydrate–antibody interactions by Yu, Henry N, Ling, Chang-Chun, Bundle, David R

“…Disaccharides 1 - 3 corresponding to the antigenic determinants of Salmonella serotypes A, B, and D 1 were synthesized in a form suited for use in biosensors…”
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A General Strategy toward S-Linked Glycopeptides by Thayer, Desiree A., Yu, Henry N., Galan, M. Carmen, Wong, Chi-Huey

“…Eine effiziente Eintopfsynthese von S‐verknüpften Glycosylaminosäuren 1 wurde entwickelt (siehe Schema; DMF=Dimethylformamid) und in der Festphasensynthese von…”
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Thiooligosaccharide Conjugate Vaccines Evoke Antibodies Specific for Native Antigens by Bundle, David R., Rich, Jamie R., Jacques, Sandra, Yu, Henry N., Nitz, Mark, Ling, Chang-Chun

“…Wenn S SO viel besser ist: Konjugierte Impfstoffe, die S‐Glycoside enthalten, induzieren kohlenhydratspezifische Antikörper, die auch mit den entsprechenden…”
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A practical route to 3,6-dideoxyhexoses by Yu, Henry N., Zhang, Ping, Ling, Chang-Chun, Bundle, David R.

“…Novel, readily scaled and practical routes for the synthesis of 3,6-dideoxy- d- xylo-hexose and 3,6-dideoxy- d- ribo-hexose and their corresponding glycosyl…”
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Thiooligosaccharide Conjugate Vaccines Evoke Antibodies Specific for Native Antigens by Bundle, David R., Rich, Jamie R., Jacques, Sandra, Yu, Henry N., Nitz, Mark, Ling, Chang‐Chun

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A General Strategy toward S‐Linked Glycopeptides by Thayer, Desiree A., Yu, Henry N., Galan, M. Carmen, Wong, Chi‐Huey

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