Search Results - "Yu, Hangxing"
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Predicting diagnostic gene expression profiles associated with immune infiltration in patients with lupus nephritis
Published in Frontiers in immunology (02-12-2022)“…To identify potential diagnostic markers of lupus nephritis (LN) based on bioinformatics and machine learning and to explore the significance of immune cell…”
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Elucidating the genetic relationship between ulcerative colitis and diabetic kidney disease: a bidirectional Mendelian randomization study
Published in Frontiers in endocrinology (Lausanne) (15-08-2024)“…Ulcerative colitis (UC) and diabetic kidney disease (DKD) are chronic disorders with multifaceted pathogenesis, posing significant challenges in clinical…”
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Differential Regulation of NF-κB-Mediated Proviral and Antiviral Host Gene Expression by Primate Lentiviral Nef and Vpu Proteins
Published in Cell reports (Cambridge) (03-02-2015)“…NF-κB is essential for effective transcription of primate lentiviral genomes and also activates antiviral host genes. Here, we show that the early protein Nef…”
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Endocytic sorting motif interactions involved in Nef-mediated downmodulation of CD4 and CD3
Published in Nature communications (05-09-2017)“…Lentiviral Nefs recruit assembly polypeptide complexes and target sorting motifs in cellular receptors to induce their internalization. While Nef-mediated CD4…”
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Efficacy of Chinese Herbal Injections for the Treatment of Primary Nephrotic Syndrome: A Bayesian Network Meta-Analysis of Randomized Controlled Trials
Published in Frontiers in pharmacology (16-10-2020)“…Considering the adverse reactions and side effects of immunosuppressive and cytotoxic drugs for the treatment of Primary Nephrotic Syndrome (PNS) and the…”
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MicroRNAs as Potential Biomarkers for the Diagnosis of Chronic Kidney Disease: A Systematic Review and Meta-Analysis
Published in Frontiers in medicine (07-02-2022)“…For Chronic Kidney Disease (CKD), the study of microRNA as a biomarker has become an exciting area, so we carried out a meta-analysis to investigate the…”
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Specific gut microbiome and metabolome changes in patients with continuous ambulatory peritoneal dialysis and comparison between patients with different dialysis vintages
Published in Frontiers in medicine (2023)“…In recent years, the role of gut microbiota and derived metabolites in renal disease has attracted more attention. It has been established that the gut…”
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Efficient Nef-Mediated Downmodulation of TCR-CD3 and CD28 Is Associated with High CD4+ T Cell Counts in Viremic HIV-2 Infection
Published in Journal of Virology (01-05-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Persistent Chlamydia trachomatis Infection of HeLa Cells Mediates Apoptosis Resistance through a Chlamydia Protease-Like Activity Factor-Independent Mechanism and Induces High Mobility Group Box 1 Release
Published in Infection and Immunity (01-01-2012)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Role of High-Mobility Group Box 1 Protein and Poly(ADP-Ribose) Polymerase 1 Degradation in Chlamydia trachomatis-Induced Cytopathicity
Published in Infection and Immunity (01-07-2010)“…As intracellular bacteria, chlamydiae block the apoptotic pathways of their host cells. However, the infection of epithelial cells causes the loss of cell…”
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Link between Primate Lentiviral Coreceptor Usage and Nef Function
Published in Cell reports (Cambridge) (27-11-2013)“…Simian immunodeficiency virus (SIVsmm) infection of sooty mangabeys (Cercocebus atys) is characterized by stable CD4+ T cell counts despite high plasma levels…”
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Emodin inhibits M1 macrophage activation that related to acute and chronic kidney injury through EGFR/MAPK pathway
Published in Functional & integrative genomics (01-08-2024)“…Background Macrophages are the main inflammatory cells involved in kidney injury and play a significant role in the development of acute kidney injury (AKI)…”
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The effects of Fushen Granule on the composition and function of the gut microbiota during Peritoneal Dialysis–Related Peritonitis
Published in Phytomedicine (Stuttgart) (01-06-2021)“…Peritoneal dialysis (PD) is an acknowledged treatment for patients with irreversible kidney failure. The treatment usually causes peritoneal dialysis–related…”
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A Network Pharmacology-Based Approach to Investigating the Mechanisms of Fushen Granule Effects on Intestinal Barrier Injury in Chronic Renal Failure
Published in Evidence-based complementary and alternative medicine (2021)“…Purpose. Fushen Granule (FSG) is a Chinese medicine prepared by doctors for treating patients with chronic renal failure, which is usually accompanied by…”
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Lentiviral Nef proteins manipulate T cells in a subset-specific manner
Published in Journal of virology (01-02-2015)“…The role of the accessory viral Nef protein as a multifunctional manipulator of the host cell that is required for effective replication of human…”
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The efficiency of Vpx-mediated SAMHD1 antagonism does not correlate with the potency of viral control in HIV-2-infected individuals
Published in Retrovirology (05-03-2013)“…The presence of a vpx gene distinguishes HIV-2 from HIV-1, the main causative agent of AIDS. Vpx degrades the restriction factor SAMHD1 to boost HIV-2…”
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