Search Results - "Yu, Francois"

Low Intensity Ultrasound Mediated Liposomal Doxorubicin Delivery Using Polymer Microbubbles by Yu, Francois T. H, Chen, Xucai, Wang, Jianjun, Qin, Bin, Villanueva, Flordeliza S

“…Cardiotoxicity is the major dose-limiting factor in the chemotherapeutic use of doxorubicin (Dox). A delivery vehicle that can be triggered to release its…”
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Effect of Acoustic Conditions on Microbubble-Mediated Microvascular Sonothrombolysis by Leeman, Jonathan E, Kim, Jong S, Yu, Francois T.H, Chen, Xucai, Kim, Kang, Wang, Jianjun, Chen, Xianghui, Villanueva, Flordeliza S, Pacella, John J

“…Abstract Ultrasound (US) mediated microbubble (MB) destruction facilitates thrombolysis of the epicardial coronary artery in acute myocardial infarction (AMI)…”
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Dynamic Behavior of Polymer Microbubbles During Long Ultrasound Tone-Burst Excitation and Its Application for Sonoreperfusion Therapy by Chen, Xianghui, Chen, Xucai, Wang, Jianjun, Yu, Francois T.H., Villanueva, Flordeliza S., Pacella, John J.

“…Ultrasound (US)–targeted microbubble (MB) cavitation (UTMC)–mediated therapies have been found to restore perfusion and enhance drug/gene delivery. Because of…”
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Inertial Cavitation Ultrasound with Microbubbles Improves Reperfusion Efficacy When Combined with Tissue Plasminogen Activator in an In Vitro Model of Microvascular Obstruction by Goyal, Akash, Yu, Francois T.H, Tenwalde, Mathea G, Chen, Xucai, Althouse, Andrew, Villanueva, Flordeliza S, Pacella, John J

“…Abstract We have previously reported that long-tone-burst, high-mechanical-index ultrasound (US) and microbubble (MB) therapy can restore perfusion in both…”
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Sonoreperfusion therapy for microvascular obstruction: A step toward clinical translation by Istvanic, Filip, Yu, Gary Z., Yu, Francois T.H., Powers, Jeff, Chen, Xucai, Pacella, John J.

“…Sonoreperfusion therapy is being developed as an intervention for the treatment of microvascular obstruction. We investigated the reperfusion efficacy of two…”
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Effect of Thrombus Composition and Viscosity on Sonoreperfusion Efficacy in a Model of Micro-Vascular Obstruction by Black, John J, Yu, Francois T.H, Schnatz, Rick G, Chen, Xucai, Villanueva, Flordeliza S, Pacella, John J

“…Abstract Distal embolization of micro-thrombi during stenting for myocardial infarction causes micro-vascular obstruction (MVO). We have previously shown that…”
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The Role of Nitric Oxide during Sonoreperfusion of Microvascular Obstruction by Yu, Francois T H, Chen, Xucai, Straub, Adam C, Pacella, John J

“…Microembolization during PCI for acute myocardial infarction can cause microvascular obstruction . MVO severely limits the success of reperfusion therapies, is…”
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Radial modulation contrast imaging using a 20-mhz single-element intravascular ultrasound catheter by Yu, Francois T.H., Villanueva, Flordeliza S., Chen, Xucai

“…Contrast-enhanced intravascular ultrasound imaging is a promising tool for the characterization of coronary vasa vasorum proliferation, which has been…”
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Radial modulation contrast imaging using a 20-mhz single-element intravascular ultrasound catheter by Yu, Francois, Villanueva, Flordeliza, Chen, Xucai

“…Contrast-enhanced intravascular ultrasound imaging is a promising tool for the characterization of coronary vasa vasorum proliferation, which has been…”
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Flexible integration of high-imaging- resolution and high-power arrays for ultrasound-induced thermal strain imaging (US-TSI) by Stephens, Douglas, Mahmoud, Ahmed, Ding, Xuan, Lucero, Steven, Dutta, Debaditya, Yu, Francois T. H., Xucai Chen, Kang Kim

“…Ultrasound-induced thermal strain imaging (USTSI) for carotid artery plaque detection requires both high imaging resolution (<;100 μm) and sufficient…”
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Sonoreperfusion Therapy Kinetics in Whole Blood Using Ultrasound, Microbubbles and Tissue Plasminogen Activator by Roos, Sebastiaan T, Yu, François T, Kamp, Otto, Chen, Xucai, Villanueva, Flordeliza S, Pacella, John J

“…Abstract Coronary intervention for myocardial infarction often results in microvascular embolization of thrombus. Sonoreperfusion therapy (SRP) using…”
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SONOREPERFUSION FOR MICROVASCULAR OBSTRUCTION USING ULTRASOUND AND MICROBUBBLES: ROLE OF NITRIC OXIDE by Yu, Francois T.H., Chen, Xucai, Villanueva, Flordeliza, Pacella, John

“…[...]we tested the hypothesis that NO plays a role in SRP by assessing reperfusion efficacy in a rat hindlimb model of MVO during blockade of endothelial NO…”
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The effect of ultrasound pulse length on microbubble cavitation induced antibody accumulation and distribution in a mouse model of breast cancer by Amate, Marie, Goldgewicht, Joseph, Sellamuthu, Balasubramanian, Stagg, John, Yu, Francois T H

“…In solid tumors, the limited diffusion of therapeutic molecules in the perivascular space is a known limitation impacting treatment efficacy. Ultrasound…”
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Targeted Anti-Cancer Provascular Therapy Using Ultrasound, Microbubbles, and Nitrite to Increase Radiotherapy Efficacy by Michon, Simon, Rodier, Francis, Yu, François T. H.

“…Hypoxia is an important mechanism of resistance to radiation therapy in many human malignancies including prostate cancer. It has been recently shown that…”
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Unifying Concepts of Statistical and Spectral Quantitative Ultrasound Techniques by Destrempes, Francois, Franceschini, Emilie, Yu, Francois T. H., Cloutier, Guy

“…Quantitative ultrasound (QUS) techniques using radiofrequency (RF) backscattered signals have been used for tissue characterization of numerous organ systems…”
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Fundamentals and Applications of Focused Ultrasound-Assisted Cancer Immune Checkpoint Inhibition for Solid Tumors by Jahangiri, Sepideh, Yu, François

“…Despite spectacular clinical successes across several cancer types, immune checkpoint inhibition is effective only in subgroups of patients and suffers from…”
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Quantitative ultrasound imaging of soft biological tissues: a primer for radiologists and medical physicists by Cloutier, Guy, Destrempes, François, Yu, François, Tang, An

“…Quantitative ultrasound (QUS) aims at quantifying interactions between ultrasound and biological tissues. QUS techniques extract fundamental physical…”
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Volumetric quantification of in vitro sonothrombolysis with microbubbles using high-resolution optical coherence tomography by Kim, Jong S, Leeman, Jonathan E, Kagemann, Larry, Yu, Francois T H, Chen, Xucai, Pacella, John J, Schuman, Joel S, Villanueva, Flordeliza S, Kim, Kang

“…Several in vitro and in vivo studies have established accelerated thrombolysis using ultrasound (US) induced microbubble (MB) cavitation. However, the…”
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Effect of Ultrasound Pulse Length on Sonoreperfusion Therapy by Yu, François T.H., Amjad, Muhammad Wahab, Mohammed, Soheb Anwar, Yu, Gary Z., Chen, Xucai, Pacella, John J.

“…In recent years, long- and short-pulse ultrasound (US)-targeted microbubble cavitation (UTMC) has been found to increase perfusion in healthy and ischemic…”
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Influence of erythrocyte aggregation on radial migration of platelet-sized spherical particles in shear flow by Guilbert, Cyrille, Chayer, Boris, Allard, Louise, Yu, François T.H., Cloutier, Guy

“…Blood platelets when activated are involved in the mechanisms of hemostasis and thrombosis, and their migration toward injured vascular endothelium…”
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