Search Results - "Yu, Dianmei"
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Analysis of differentially expressed genes discovers Latroeggtoxin VI-induced changes and SYNJ1 as a main target in PC12 cells
Published in BMC genomics (04-09-2023)“…Abstract Background Previous preliminary work found that Latroeggtoxin-VI (LETX-VI), a proteinaceous neurotoxin from the eggs of spider Latrodectus…”
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Effects of latroeggtoxin-VI on dopamine and α-synuclein in PC12 cells and the implications for Parkinson's disease
Published in Biological research (16-03-2024)“…Parkinson's disease (PD) is characterized by death of dopaminergic neurons leading to dopamine deficiency, excessive α-synuclein facilitating Lewy body…”
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Pull-Down Assay-Guided Insights into the Effects of Latroeggtoxin-VI on Nerve Cells
Published in Toxins (12-02-2021)“…Latroeggtoxin-VI (LETX-VI) is a peptide neurotoxin newly found from the eggs of spider To explore the mechanism of action of the LETX-VI on nerve cells, the…”
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Anti-Breast Cancer Activity of Latroeggtoxin-V Mined from the Transcriptome of Spider Latrodectus tredecimguttatus Eggs
Published in Toxins (02-11-2018)“…As a black widow spider, has poisonous components not only in venomous glands but also in eggs. Our previous work had carried out a transcriptome analysis of…”
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Rab3 and synaptotagmin proteins in the regulation of vesicle fusion and neurotransmitter release
Published in Life sciences (1973) (15-11-2022)Get full text
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Molecular basis and mechanism underlying the insecticidal activity of venoms and toxins from Latrodectus spiders
Published in Pest management science (01-02-2019)“…Latrodectus species are among the most venomous of spiders, with abundant toxic proteinaceous components in their venomous glands and other tissues, as well as…”
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Effects of latroeggtoxin-VI on dopamine and [alpha]-synuclein in PC12 cells and the implications for Parkinson's disease
Published in Biological research (16-03-2024)“…Parkinson's disease (PD) is characterized by death of dopaminergic neurons leading to dopamine deficiency, excessive [alpha]-synuclein facilitating Lewy body…”
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Synaptotagmin 1-mediated cell membrane penetration and dopamine release enhancement by latroeggtoxin-VI
Published in International journal of biological macromolecules (01-09-2022)“…Latroeggtoxin-VI (LETX-VI), a proteinaceous neurotoxin mined from the egg transcriptome of spider L. tredecimguttatus, was previously found to promote the…”
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Biochemical and cytotoxic evaluation of latroeggtoxin‐VI against PC12 cells
Published in Journal of biochemical and molecular toxicology (01-08-2021)“…Latroeggtoxin‐VI (LETX‐VI) is a peptide neurotoxin discovered from Latrodectus tredecimguttatus eggs. In the current study, the action features of the…”
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Gene cloning, heterologous expression and activity identification of latroeggtoxin-
Published in Sheng wu gong cheng xue bao = Chinese journal of biotechnology (25-02-2021)“…One of the distinct characters of Latrodectus tredecimguttatus is that its toxic components exist not only in the venomous glands, but also in the tissues…”
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