Search Results - "Yu, Deyang"
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The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine
Published in Cell metabolism (04-05-2021)“…Low-protein diets promote metabolic health in rodents and humans, and the benefits of low-protein diets are recapitulated by specifically reducing dietary…”
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Restoration of metabolic health by decreased consumption of branched‐chain amino acids
Published in The Journal of physiology (15-02-2018)“…Key points We recently found that feeding healthy mice a diet with reduced levels of branched-chain amino acids (BCAAs), which are associated with insulin…”
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3
Theoretical studies on the two-photon absorption of II–VI semiconductor nano clusters
Published in Scientific reports (07-01-2022)“…Semiconductor clusters, Zn n O n , Zn n S n , and Cd n S n (n = 2–8), were optimized and the corresponding stable structures were acquired. The symmetry, bond…”
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4
A novel rapamycin analog is highly selective for mTORC1 in vivo
Published in Nature communications (19-07-2019)“…Rapamycin, an inhibitor of mechanistic Target Of Rapamycin Complex 1 (mTORC1), extends lifespan and shows strong potential for the treatment of age-related…”
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5
Feedforward cysteine regulation maintains melanoma differentiation state and limits metastatic spread
Published in Cell reports (Cambridge) (23-07-2024)“…The inherent ability of melanoma cells to alter the differentiation-associated transcriptional repertoire to evade treatment and facilitate metastatic spread…”
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6
Sex and genetic background define the metabolic, physiologic, and molecular response to protein restriction
Published in Cell metabolism (01-02-2022)“…Low-protein diets promote metabolic health in humans and rodents. Despite evidence that sex and genetic background are key factors in the response to diet,…”
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Epigenetic suppression of PGC1α (PPARGC1A) causes collateral sensitivity to HMGCR-inhibitors within BRAF-treatment resistant melanomas
Published in Nature communications (05-06-2023)“…While targeted treatment against BRAF(V600E) improve survival for melanoma patients, many will see their cancer recur. Here we provide data indicating that…”
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Lifelong restriction of dietary branched-chain amino acids has sex-specific benefits for frailty and life span in mice
Published in Nature aging (01-01-2021)“…Protein-restricted diets promote health and longevity in many species. While the precise components of a protein-restricted diet that mediate the beneficial…”
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9
Lipid-Lowering and Antioxidant Effects of Self-Assembled Astaxanthin-Anthocyanin Nanoparticles on High-Fat Caenorhabditis elegans
Published in Foods (07-02-2024)“…Obesity has become a serious global public health risk threatening millions of people. In this study, the astaxanthin-anthocyanin nanoparticles (AXT-ACN NPs)…”
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10
Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence
Published in Molecular cell (16-04-2020)“…S-adenosylmethionine (SAM) is the methyl-donor substrate for DNA and histone methyltransferases that regulate epigenetic states and subsequent gene expression…”
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Calorie-Restriction-Induced Insulin Sensitivity Is Mediated by Adipose mTORC2 and Not Required for Lifespan Extension
Published in Cell reports (Cambridge) (01-10-2019)“…Calorie restriction (CR) extends the healthspan and lifespan of diverse species. In mammals, a broadly conserved metabolic effect of CR is improved insulin…”
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12
Dosimetric Comparison of Helical Tomotherapy, Volume-Modulated Arc Therapy, and Fixed-Field Intensity-Modulated Radiation Therapy in Locally Advanced Nasopharyngeal Carcinoma
Published in Frontiers in oncology (05-11-2021)“…To compare the dosimetric parameters of different radiotherapy plans [helical tomotherapy (HT), volume-modulated arc therapy (VMAT), and fixed-field…”
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13
Facilely synthesized N-doped graphene sheets and its ferromagnetic origin
Published in Chinese chemical letters (01-12-2021)“…Inducing ferromagnetism into graphene is vital today because it has a wide range of applications such as spintronics devices and magnetic memory devices. In…”
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14
The influence of relativistic, Breit interaction, and QED effects on the 1s22p2 and 2s2p3 energy levels of Be-like (4≤Z≤74) isoelectronic sequence
Published in The European physical journal. D, Atomic, molecular, and optical physics (2023)“…The excitation energies of the Be-like ions (4 ≤ Z ≤ 74) doubly excited state 1 s 2 2 p 2 and doubly core-excited state 2 s 2 p 3 are calculated using the…”
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15
Preparation and Evaluation of Undaria pinnatifida Nanocellulose in Fabricating Pickering Emulsions for Protection of Astaxanthin
Published in Foods (18-03-2022)“…Pickering emulsions stabilized from natural sources are often used to load unstable bio-active ingredients, such as astaxanthin (AXT), to improve their…”
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16
Facile preparation of hydrogenated graphene by hydrothermal methods and the investigation of its ferromagnetism
Published in Chinese chemical letters (01-11-2021)“…Hydrogenated graphene (HG) was prepared by hydrothermal method and the ferromagnetism of the HG was studied. [Display omitted] In this paper, a hydrothermal…”
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17
The Metabolic Response to a Low Amino Acid Diet is Independent of Diet-Induced Shifts in the Composition of the Gut Microbiome
Published in Scientific reports (11-01-2019)“…Obesity and type 2 diabetes are increasing in prevalence around the world, and there is a clear need for new and effective strategies to promote metabolic…”
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18
Nanocarrier from water extract solution of Auricularia auricula for zinc delivery
Published in Food hydrocolloids for health (01-12-2022)“…•FNs from Auricularia auricula water extract solution were used as zinc nanocarrier.•Zn(II)-FNs were synthesized simply by a one-step water bath heating…”
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Synthesis of few-layer N-doped graphene from expandable graphite with melamine and its application in supercapacitors
Published in Chinese chemical letters (01-02-2020)“…Few-layer N-doped graphene synthesis from melamine and expandable graphite exhibited extraordinary specific capacitance together with excellent cycling…”
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20
Research on High-Precision Position Detection Based on a Driven Laser Spot in an Extreme Ultraviolet Light Source
Published in Photonics (01-01-2024)“…Laser-spot-location detection technology based on photodetectors is widely used in the aerospace, medical, military and communication fields. However, most of…”
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