Search Results - "Yu, Dae–Yeul"

Inactivation of Peroxiredoxin I by Phosphorylation Allows Localized H2O2 Accumulation for Cell Signaling by Woo, Hyun Ae, Yim, Sun Hee, Shin, Dong Hae, Kang, Dongmin, Yu, Dae-Yeul, Rhee, Sue Goo

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Relevance of reactive oxygen species in liver disease observed in transgenic mice expressing the hepatitis B virus X protein by Yu, Dae-Yeul

“…The hepatitis B virus (HBV) infects approximately 240 million people worldwide, causing chronic liver disease (CLD) and liver cancer. Although numerous studies…”
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The Cxadr–Adam10 complex plays pivotal roles in tight junction integrity and early trophoblast development in mice by Jeong, Yelin, Ock, Sun‐A, Yoo, Jae Gyu, Yu, Dae‐Yeul, Choi, Inchul

“…Understanding preimplantation embryo development has important implications for assisted reproductive technologies (ARTs) after the introduction of in vitro…”
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Aberrant enhancer hypomethylation contributes to hepatic carcinogenesis through global transcriptional reprogramming by Xiong, Lei, Wu, Feng, Wu, Qiong, Xu, Liangliang, Cheung, Otto K., Kang, Wei, Mok, Myth T., Szeto, Lemuel L. M., Lun, Cheuk-Yin, Lung, Raymond W., Zhang, Jinglin, Yu, Ken H., Lee, Sau-Dan, Huang, Guangcun, Wang, Chiou-Miin, Liu, Joseph, Yu, Zhuo, Yu, Dae-Yeul, Chou, Jian-Liang, Huang, Wan-Hong, Feng, Bo, Cheung, Yue-Sun, Lai, Paul B., Tan, Patrick, Wong, Nathalie, Chan, Michael W., Huang, Tim H., Yip, Kevin Y., Cheng, Alfred S., To, Ka-Fai

“…Hepatocellular carcinomas (HCC) exhibit distinct promoter hypermethylation patterns, but the epigenetic regulation and function of transcriptional enhancers…”
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Interaction of tankyrase and peroxiredoxin II is indispensable for the survival of colorectal cancer cells by Kang, Dong Hoon, Lee, Doo Jae, Lee, Sunmi, Lee, So-Young, Jun, Yukyung, Kim, Yerin, Kim, Youngeun, Lee, Ju-Seog, Lee, Dae-Kee, Lee, Sanghyuk, Jho, Eek-Hoon, Yu, Dae-Yeul, Kang, Sang Won

“…Mammalian 2-Cys peroxiredoxin (Prx) enzymes are overexpressed in most cancer tissues, but their specific signaling role in cancer progression is poorly…”
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Peroxiredoxin II Is Essential for Maintaining Stemness by Redox Regulation in Liver Cancer Cells by Kwon, Taeho, Bak, Yesol, Park, Young‐Ho, Jang, Gyu‐Beom, Nam, Jeong‐Seok, Yoo, Jeong Eun, Park, Young Nyun, Bak, In Seon, Kim, Jin‐Man, Yoon, Do‐Young, Yu, Dae‐Yeul

“…Redox regulation in cancer stem cells (CSCs) is viewed as a good target for cancer therapy because redox status plays an important role in cancer stem‐cell…”
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Regulation of habenular G-protein gamma 8 on learning and memory via modulation of the central acetylcholine system by Lee, Hyun-ju, Choi, Tae-Ik, Kim, Yong-Min, Lee, Soonje, Han, Bing, Bak, In Seon, Moon, Sun Ae, Yu, Dae-Yeul, Shin, Ki Soon, Kwon, Yunhee Kim, Moon, Cheil, Ryu, Jae Hwan, Hoe, Hyang-Sook, Kim, Cheol-Hee, Shim, Insop

“…Guanine nucleotide binding protein (G protein) gamma 8 (Gng8) is a subunit of G proteins and expressed in the medial habenula (MHb) and interpeduncular nucleus…”
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Concerted action of sulfiredoxin and peroxiredoxin I protects against alcohol‐induced oxidative injury in mouse liver by Bae, Soo Han, Sung, Su Haeng, Cho, Eun Jung, Lee, Se Kyoung, Lee, Hye Eun, Woo, Hyun Ae, Yu, Dae‐Yeul, Kil, In Sup, Rhee, Sue Goo

“…Peroxiredoxins (Prxs) are peroxidases that catalyze the reduction of reactive oxygen species (ROS). The active site cysteine residue of members of the 2‐Cys…”
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Hepatitis B Virus X Protein Induces Hepatic Steatosis Via Transcriptional Activation of SREBP1 and PPARγ by Kim, Kook Hwan, Shin, Hye–Jun, Kim, Kyeongjin, Choi, Hyun Mi, Rhee, Sang Hoon, Moon, Hyung–Bae, Kim, Hyeong Hoe, Yang, Ung Suk, Yu, Dae–Yeul, Cheong, Jaehun

“…Background & Aims: Hepatic steatosis occurs frequently in patients with chronic hepatitis B virus (HBV) or chronic hepatitis C virus (HCV) infection. Recently,…”
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AK2 is an AMP-sensing negative regulator of BRAF in tumorigenesis by Kim, Hyunjoo, Jeong, Muhah, Na, Do-Hyeong, Ryu, Shin-Hyeon, Jeong, Eun Il, Jung, Kwangmin, Kang, Jaemin, Lee, Ho-June, Sim, Taebo, Yu, Dae-Yeul, Yu, Hee Chul, Cho, Baik-Hwan, Jung, Yong-Keun

“…The RAS–BRAF signaling is a major pathway of cell proliferation and their mutations are frequently found in human cancers. Adenylate kinase 2 (AK2), which…”
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Loss of peroxiredoxin-2 exacerbates eccentric contraction-induced force loss in dystrophin-deficient muscle by Olthoff, John T., Lindsay, Angus, Abo-Zahrah, Reem, Baltgalvis, Kristen A., Patrinostro, Xiaobai, Belanto, Joseph J., Yu, Dae-Yeul, Perrin, Benjamin J., Garry, Daniel J., Rodney, George G., Lowe, Dawn A., Ervasti, James M.

“…Force loss in skeletal muscle exposed to eccentric contraction is often attributed to injury. We show that EDL muscles from dystrophin-deficient mdx mice…”
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Depression-like behaviors induced by defective PTPRT activity through dysregulated synaptic functions and neurogenesis by Lim, So-Hee, Shin, Sangyep, Kim, Myoung-Hwan, Kim, Eung Chang, Lee, Da Yong, Moon, Jeonghee, Park, Hye-Yeon, Ryu, Young-Kyoung, Kang, Young-Mi, Kang, Yu Jeong, Kim, Tae Hwan, Lee, Na-Yoon, Kim, Nam-Soon, Yu, Dae-Yeul, Shim, Insop, Gondo, Yoichi, Satake, Masanobu, Kim, Eunhee, Kim, Kyoung-Shim, Min, Sun Seek, Lee, Jae-Ran

“…PTPRT has been known to regulate synaptic formation and dendritic arborization of hippocampal neurons. null and -D401A mutant mice displayed enhanced…”
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Yin Yang 1-mediated epigenetic silencing of tumour-suppressive microRNAs activates nuclear factor-κB in hepatocellular carcinoma by Tsang, Daisy PF, Wu, William KK, Kang, Wei, Lee, Ying-Ying, Wu, Feng, Yu, Zhuo, Xiong, Lei, Chan, Anthony W, Tong, Joanna H, Yang, Weiqin, Li, May SM, Lau, Suki S, Li, Xiangchun, Lee, Sau-Dan, Yang, Yihua, Lai, Paul BS, Yu, Dae-Yeul, Xu, Gang, Lo, Kwok-Wai, Chan, Matthew TV, Wang, Huating, Lee, Tin L, Yu, Jun, Wong, Nathalie, Yip, Kevin Y, To, Ka-Fai, Cheng, Alfred SL

“…Enhancer of zeste homolog 2 (EZH2) catalyses histone H3 lysine 27 trimethylation (H3K27me3) to silence tumour‐suppressor genes in hepatocellular carcinoma…”
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Identification of Gng8-expressing cell types in the MHb and IPN by Lee, Hyun-ju, Choi, Tae-Ik, Kim, Yong-Min, Lee, Soonje, Han, Bing, Bak, In Seon, Moon, Sun Ae, Yu, Dae-Yeul, Shin, Ki Soon, Kwon, Yunhee Kim, Moon, Cheil, Ryu, Jae Hwan, Hoe, Hyang-Sook, Kim, Cheol-Hee, Shim, Insop

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Leukotriene B4 receptor-2 contributes to KRAS-driven lung tumor formation by promoting interleukin-6-mediated inflammation by Jang, Jae-Hyun, Park, Donghwan, Park, Guen-soo, Kwak, Dong-Wook, Park, JaeIn, Yu, Dae-Yeul, You, Hye Jin, Kim, Jae-Hong

“…Although lung cancer is the leading cause of cancer-related deaths worldwide and KRAS is the most frequently mutated oncogene in lung cancer cases, the…”
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Peroxiredoxin 2 Deficiency Exacerbates Atherosclerosis in Apolipoprotein E–Deficient Mice by Park, Jong-Gil, Yoo, Ji-Young, Jeong, Se-Jin, Choi, Jae-Hoon, Lee, Mi-Ran, Lee, Mi-Ni, Hwa Lee, Jeong, Kim, Hyoung Chin, Jo, Hanjoong, Yu, Dae-Yeul, Kang, Sang Won, Rhee, Sue Goo, Lee, Mun-Han, Oh, Goo Taeg

“…RATIONALE:Peroxiredoxin 2 (Prdx2), a thiol-specific peroxidase, has been reported to regulate proinflammatory responses, vascular remodeling, and global…”
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Inhibition of MKK7–JNK by the TOR Signaling Pathway Regulator-Like Protein Contributes to Resistance of HCC Cells to TRAIL-Induced Apoptosis by Song, In Sung, Jun, Soo Young, Na, Hee–Jun, Kim, Hyun–Taek, Jung, So Young, Ha, Ga Hee, Park, Young–Ho, Long, Liang Zhe, Yu, Dae–Yeul, Kim, Jin–Man, Kim, Joo Heon, Ko, Jeong–Heon, Kim, Cheol–Hee, Kim, Nam–Soon

“…Background & Aims The TOR signaling pathway regulator-like (TIPRL) protein, the mammalian ortholog of yeast TIP41, was identified in an expression profiling…”
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The effects of disruption of genes for peroxiredoxin-2, glutathione peroxidase-1, and catalase on erythrocyte oxidative metabolism by Johnson, Robert M., Ho, Ye-Shih, Yu, Dae-Yeul, Kuypers, Frans A., Ravindranath, Yaddanapudi, Goyette, Gerard W.

“…Peroxiredoxin-2 (Prdx2), a potent peroxide reductant, is the third most abundant protein in the erythrocyte and might be expected to play a major role in the…”
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Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene by Agrawal-Singh, Shuchi, Isken, Fabienne, Agelopoulos, Konstantin, Klein, Hans-Ulrich, Thoennissen, Nils H., Koehler, Gabriele, Hascher, Antje, Bäumer, Nicole, Berdel, Wolfgang E., Thiede, Christian, Ehninger, Gerhard, Becker, Anke, Schlenke, Peter, Wang, Yipeng, McClelland, Michael, Krug, Utz, Koschmieder, Steffen, Büchner, Thomas, Yu, Dae-Yeul, Singh, Shailendra Vikram, Hansen, Klaus, Serve, Hubert, Dugas, Martin, Müller-Tidow, Carsten

“…With the use of ChIP on microarray assays in primary leukemia samples, we report that acute myeloid leukemia (AML) blasts exhibit significant alterations in…”
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Peroxiredoxin II is essential for preventing hemolytic anemia from oxidative stress through maintaining hemoglobin stability by Han, Ying-Hao, Kim, Sun-Uk, Kwon, Tae-Ho, Lee, Dong-Seok, Ha, Hye-Lin, Park, Doo-Sang, Woo, Eui-Jeon, Lee, Sang-Hee, Kim, Jin-Man, Chae, Ho-Byoung, Lee, Sang Yeol, Kim, Bo Yeon, Yoon, Do Young, Rhee, Sue Goo, Fibach, Eitan, Yu, Dae-Yeul

“…► Prx II functions are modulated in response to oxidative stress in diseased RBCs. ► Prx II can bind to Hb and protect Hb from oxidative-induced denaturation…”
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