Search Results - "Yu, Chungping"

Huperzine A suppresses absence seizures in the genetic absence epilepsy rat from Strasbourg (GAERS) model of genetic generalized epilepsy with absence seizures by Casillas‐Espinosa, Pablo M., Garcia‐Olivares, Jennie, Li, Rui, Li, Crystal, Yu, Chungping, Formella, Andrea E., O'Brien, Terence J.

“…Objective We evaluated huperzine A treatment in the Genetic Absence Epilepsy Rat from Strasbourg (GAERS) model of genetic generalized epilepsy (GGE) with…”
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A rapid method for quantitatively estimating metabolites in human plasma in the absence of synthetic standards using a combination of liquid chromatography/mass spectrometry and radiometric detection by Yu, ChungPing, Chen, Cathy L., Gorycki, Frances L., Neiss, Thomas G.

“…An approach to estimating the levels of drug‐related metabolites in human plasma in the absence of synthesized chemical standards has been developed…”
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Metabolism and in vitro drug-drug interaction assessment of viloxazine by Yu, Chungping

“…Viloxazine is currently being developed as a treatment for attention deficit/hyperactivity disorder (ADHD). The aim of these studies is to update the…”
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Metabolism and in vitro drug-drug interaction assessment of viloxazine by Yu, Chungping

“…Viloxazine is currently being developed as a treatment for attention deficit/hyperactivity disorder (ADHD). The aim of these studies is to update the…”
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Viloxazine Increases Cortical Serotonin Without Inhibiting Serotonin Reuptake at Doses Used to Treat ADHD by Garcia-Olivares, Jennie, Yegla, Brittney, Zweibaum, David, Koch, Jennifer, Bymaster, Frank, Yu, ChungPing

“…Abstract Background Most FDA-approved ADHD treatments increase norepinephrine (NE) and dopamine (DA); however, our prior preclinical studies of the…”
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Characterization of Viloxazine Effects on Cortical Serotonin Neurotransmission at Doses Relevant for ADHD Treatment by Garcia-Olivares, Jennie, Yegla, Brittney, Earnest, Jami, Maletic, Vladimir, Yu, ChungPing

“…Abstract Introduction Most ADHD treatments are thought to be effective due to augmentation of dopamine (DA) and norepinephrine (NE). Our prior preclinical…”
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Viloxazine in the Management of CNS Disorders: A Historical Overview and Current Status by Findling, Robert L., Candler, Shawn A., Nasser, Azmi F., Schwabe, Stefan, Yu, Chungping, Garcia-Olivares, Jennie, O’Neal, Welton, Newcorn, Jeffrey H.

“…Viloxazine has a long history of clinical use in Europe as an antidepressant, and has recently been repurposed into an extended-release form for the treatment…”
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P147 - Structural elucidation of the major human metabolites of viloxazine by Barton, Eleanor, Cooke, Ray, Williams, Dylan, Yu, Chungping

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New Insights into the Mechanism of Action of Viloxazine: Serotonin and Norepinephrine Modulating Properties by Yu, Chungping, Garcia-Olivares, Jennie, Candler, Shawn, Schwabe, Stefan, Maletic, Vladimir

“…Viloxazine was historically described as a norepinephrine reuptake inhibitor (NRI). Since NRIs have previously demonstrated efficacy in attention…”
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Viloxazine Increases Extracellular Concentrations of Norepinephrine, Dopamine, and Serotonin in the Rat Prefrontal Cortex at Doses Relevant for the Treatment of Attention-Deficit/Hyperactivity Disorder by Garcia-Olivares, Jennie, Yegla, Brittney, Bymaster, Frank P, Earnest, Jami, Koch, Jennifer, Yu, Chungping, Rubin, Jonathan

“…Viloxazine ER (viloxazine extended-release capsules; Qelbree ), a nonstimulant attention-deficit/hyperactivity disorder (ADHD) treatment, has known activity as…”
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In vitro pharmacological characterization of SPN-810M (molindone) by Yu, Chungping, Gopalakrishnan, Gopakumar

“…Impulsive aggression (IA) is considered a maladaptive form of aggression that is reactive and overt and occurs outside of the acceptable social context. Many…”
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A proposed anti-maladaptive aggression agent classification: improving our approach to treating impulsive aggression by Robb, Adelaide S., Schwabe, Stefan, Ceresoli-Borroni, Gianpiera, Nasser, Azmi, Yu, Chungping, Marcus, Ronald, Candler, Shawn A., Findling, Robert L.

“…Proper drug categorization enables clinicians to readily identify the agents most appropriate for patients in need. Currently, patients with maladaptive…”
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Response to comments on “Reproductive toxicology studies supporting the safety of molindone, a dopamine receptor antagonist” by Gopalakrishnan, Gopakumar, Ganiger, Shivaputhrappa, White, Tacey E. K., Yu, Chungping

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Reproductive toxicology studies supporting the safety of molindone, a dopamine receptor antagonist by Gopalakrishnan, Gopakumar, Ganiger, Shivaputhrappa, White, Tacey E. K., Yu, Chungping

“…Background An extended‐release molindone (a dopamine D2 and serotonin antagonist) is currently being developed as a novel treatment for impulsive aggression…”
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