Search Results - "Yu, Boyi"
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m6ATM: a deep learning framework for demystifying the m6A epitranscriptome with Nanopore long-read RNA-seq data
Published in Briefings in bioinformatics (23-09-2024)“…Abstract N6-methyladenosine (m6A) is one of the most abundant and well-known modifications in messenger RNAs since its discovery in the 1970s. Recent studies…”
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Role of LncRNA H19 in tumor progression and treatment
Published in Molecular and cellular probes (01-06-2024)“…As one of the earliest discovered lncRNA molecules, lncRNA H19 is usually expressed in large quantities during embryonic development and is involved in cell…”
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Subpopulations of hypocretin/orexin neurons differ in measures of their cell proliferation, dynorphin co-expression, projections, and response to embryonic ethanol exposure
Published in Scientific reports (25-05-2023)“…Numerous studies in animals demonstrate that embryonic exposure to ethanol (EtOH) at low-moderate doses stimulates neurogenesis and increases the number of…”
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4
Embryonic ethanol exposure and optogenetic activation of hypocretin neurons stimulate similar behaviors early in life associated with later alcohol consumption
Published in Scientific reports (06-02-2024)“…The initiation of alcohol use early in life is one of the strongest predictors of developing a future alcohol use disorder. Clinical studies have identified…”
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5
Neuronal chemokine concentration gradients mediate effects of embryonic ethanol exposure on ectopic hypocretin/orexin neurons and behavior in zebrafish
Published in Scientific reports (26-01-2023)“…Embryonic ethanol exposure in zebrafish and rats, while stimulating hypothalamic hypocretin/orexin (Hcrt) neurons along with alcohol consumption and related…”
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6
Ferroptosis: a novel regulated cell death participating in cellular stress response, radiotherapy, and immunotherapy
Published in Experimental hematology & oncology (27-07-2023)“…Ferroptosis is a regulated cell death mode triggered by iron-dependent toxic membrane lipid peroxidation. As a novel cell death modality that is…”
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Modification of BCLX pre-mRNA splicing has antitumor efficacy alone or in combination with radiotherapy in human glioblastoma cells
Published in Cell death & disease (21-02-2024)“…Dysregulation of anti-apoptotic and pro-apoptotic protein isoforms arising from aberrant splicing is a crucial hallmark of cancers and may contribute to…”
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8
The Neurobiology of Infant Attachment-Trauma and Disruption of Parent-Infant Interactions
Published in Frontiers in behavioral neuroscience (22-07-2022)“…Current clinical literature and supporting animal literature have shown that repeated and profound early-life adversity, especially when experienced within the…”
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Pyroptotic cell death: an emerging therapeutic opportunity for radiotherapy
Published in Cell death discovery (16-01-2024)“…Pyroptotic cell death, an inflammatory form of programmed cell death (PCD), is emerging as a potential therapeutic opportunity for radiotherapy (RT). RT is…”
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10
New mechanism of LncRNA: In addition to act as a ceRNA
Published in Non-coding RNA research (01-12-2024)“…Long non-coding RNAs (LncRNAs) are a class of RNA molecules with nucleic acid lengths ranging from 200 bp to 100 kb that cannot code for proteins, which are…”
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Therapeutic Efficacy of Carbon Ion Irradiation Enhanced by 11-MUA-Capped Gold Nanoparticles: An in vitro and in vivo Study
Published in International journal of nanomedicine (01-01-2021)“…Gold nanoparticles (AuNPs) are widely studied as radiosensitizers, but their radiosensitization in carbon ion radiotherapy is unsatisfactory. There is a lack…”
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12
Carrier systems of radiopharmaceuticals and the application in cancer therapy
Published in Cell death discovery (09-01-2024)“…Radiopharmaceuticals play a vital role in cancer therapy. The carrier of radiopharmaceuticals can precisely locate and guide radionuclides to the target, where…”
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13
Role of Chemokine Cxcl12a in Mediating the Stimulatory Effects of Ethanol on Embryonic Development of Subpopulations of Hypocretin/Orexin Neurons and Their Projections
Published in Cells (Basel, Switzerland) (16-05-2023)“…Studies in zebrafish and rats show that embryonic ethanol exposure at low-moderate concentrations stimulates hypothalamic neurons expressing hypocretin/orexin…”
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14
RSPO3 regulates the radioresistance of Non-Small cell lung cancer cells via NLRP3 Inflammasome-Mediated pyroptosis
Published in Radiotherapy and oncology (01-11-2024)“…•Uncovered RSPO3 as a key to increasing the sensitivity of NSCLC cells to radiation, counteracting radioresistance.•RSPO3 is downregulated in radioresistant…”
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A positive feedback circuit comprising p21 and HIF‐1α aggravates hypoxia‐induced radioresistance of glioblastoma by promoting Glut1/LDHA‐mediated glycolysis
Published in The FASEB journal (01-03-2022)“…The radioresistance induced by hypoxia is the major obstacle in the successful treatment of cancer radiotherapy. p21 was initially identified as a widespread…”
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Astatine-211 and actinium-225: two promising nuclides in targeted alpha therapy
Published in Acta biochimica et biophysica Sinica (26-11-2024)“…Nuclear medicine therapy offers a promising approach for tumor treatment, as the energy emitted during radionuclide decay causes irreparable damage to tumor…”
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Killing two birds with one stone: Abscopal effect mechanism and its application prospect in radiotherapy
Published in Critical reviews in oncology/hematology (01-04-2024)“…Abscopal effects are characterized by the emergence of neoplasms in regions unrelated to the primary radiation therapy site, displaying a gradual attenuation…”
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CircZNF208 enhances the sensitivity to X-rays instead of carbon-ions through the miR-7-5p /SNCA signal axis in non-small-cell lung cancer cells
Published in Cellular signalling (01-08-2021)“…Mounting evidence suggests that circular RNAs (circRNAs) are closely related to the regulation of gene expression during tumour development. However, the role…”
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Embryonic ethanol exposure induces ectopic Hcrt and MCH neurons outside hypothalamus in rats and zebrafish: Role in ethanol‐induced behavioural disturbances
Published in Addiction biology (01-11-2022)“…Embryonic exposure to ethanol increases the risk for alcohol use disorder in humans and stimulates alcohol‐related behaviours in different animal models…”
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Gadolinium Oxide Nanoparticles Reinforce the Fractionated Radiotherapy-Induced Immune Response in Tri-Negative Breast Cancer via cGAS-STING Pathway
Published in International journal of nanomedicine (01-01-2023)“…Radiotherapy is a widely recognized first-line clinical treatment for cancer, but its efficacy may be impeded by the radioresistance of advanced tumors. It is…”
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