Search Results - "Yu, Anan"

Protein aggregation can inhibit clathrin-mediated endocytosis by chaperone competition by Yu, Anan, Shibata, Yoko, Shah, Bijal, Calamini, Barbara, Lo, Donald C, Morimoto, Richard I

“…Protein conformational diseases exhibit complex pathologies linked to numerous molecular defects. Aggregation of a disease-associated protein causes the…”
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Tau protein aggregates inhibit the protein-folding and vesicular trafficking arms of the cellular proteostasis network by Yu, Anan, Fox, Susan G., Cavallini, Annalisa, Kerridge, Caroline, O’Neill, Michael J., Wolak, Joanna, Bose, Suchira, Morimoto, Richard I.

“…Tauopathies are a diverse class of neurodegenerative diseases characterized by the formation of insoluble tau aggregates and the loss of cellular function and…”
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Research on Organic Carbon and Elemental Carbon Distribution Characteristics and Their Influence on Fine Particulate Matter (PM2.5) in Changchun City by Ju Wang, Anan Yu, Le Yang, Chunsheng Fang

“…In order to understand the distribution characteristics of organic carbon (OC) and elemental carbon (EC) in PM2.5 in Changchun; China; PM2.5 samples were…”
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Structural Analysis of the Interaction between Dishevelled2 and Clathrin AP-2 Adaptor, A Critical Step in Noncanonical Wnt Signaling by Yu, Anan, Xing, Yi, Harrison, Stephen C., Kirchhausen, Tomas

“…Wnt association with its receptor, Frizzled (Fz), and recruitment by the latter of an adaptor, Dishevelled (Dvl), initiates signaling through at least two…”
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Association of Dishevelled with the Clathrin AP-2 Adaptor Is Required for Frizzled Endocytosis and Planar Cell Polarity Signaling by Yu, Anan, Rual, Jean-François, Tamai, Keiko, Harada, Yuko, Vidal, Marc, He, Xi, Kirchhausen, Tomas

“…Upon activation by Wnt, the Frizzled receptor is internalized in a process that requires the recruitment of Dishevelled. We describe a novel interaction…”
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A motif in the clathrin heavy chain required for the Hsc70/auxilin uncoating reaction by Rapoport, Iris, Boll, Werner, Yu, Anan, Böcking, Till, Kirchhausen, Tom

“…The 70-kDa heat-shock cognate protein (Hsc70) chaperone is an ATP-dependent "disassembly enzyme" for many subcellular structures, including clathrin-coated…”
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Stimulation of Phosphatidylserine Biosynthesis and Facilitation of UV-induced Apoptosis in Chinese Hamster Ovary Cells Overexpressing Phospholipid Scramblase 1 by Yu, Anan, McMaster, Christopher R, Byers, David M, Ridgway, Neale D, Cook, Harold W

“…Members of the phospholipid scramblase (PLSCR) family play active roles in altering lipid asymmetry at the plasma membrane including phosphatidylserine…”
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Challenging Proteostasis: Role of the Chaperone Network to Control Aggregation-Prone Proteins in Human Disease by Sinnige, Tessa, Yu, Anan, Morimoto, Richard I

“…Protein homeostasis (Proteostasis) is essential for correct and efficient protein function within the living cell. Among the critical components of the…”
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Resistance to UV-induced apoptosis in Chinese-hamster ovary cells overexpressing phosphatidylserine synthases by Yu, Anan, McMaster, Christopher R, Byers, David M, Ridgway, Neale D, Cook, Harold W

“…Externalization of PtdSer (phosphatidylserine) is an important event in signalling removal of apoptotic cells. In contrast with previous work [Yu, Byers,…”
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HaloTag as a substrate-based macroautophagy reporter by Xiao, Qiang, Cruz, Gabrielle, Botham, Rachel, Fox, Susan G, Yu, Anan, Allen, Seth, Morimoto, Richard I, Kelly, Jeffery W

“…Macroautophagy is a conserved cellular degradation pathway that, upon upregulation, confers resilience toward various stress conditions, including protection…”
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Lactobacillus acidophilus and Bacillus subtilis significantly change the growth performance, serum immunity and cecal microbiota of Cherry Valley ducks during the fattening period by Zhang, Menghui, Yu, Anan, Wu, Hongzhi, Xiong, Xiaolan, Li, Jianhui, Chen, Li

“…This study explored the effects of a Bacillus subtilis and Lactobacillus acidophilus mixture containing the co-fermented products of the two probiotics on…”
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The efficacy of nimodipine drug delivery using mPEG-PLA micelles and mPEG-PLA/TPGS mixed micelles by Huang, Shuling, Yu, Xiaohong, Yang, Linlin, Song, Fenglan, Chen, Gang, Lv, Zhufen, Li, Tiao, Chen, De, Zhu, Wanhua, Yu, Anan, Zhang, Yongming, Yang, Fan

“…In order to develop and compare mPEG-PLA micelles and mPEG-PLA/TPGS mixed micelles, with the intention to develop a highly efficient formulation for nimodipine…”
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Dry Gel Conversion Method for the Synthesis of Organic–Inorganic Hybrid MOR Zeolites with Modifiable Catalytic Activities by Zhou, Dan, Lu, Xinhuan, Xu, Jun, Yu, Anan, Li, Jiyang, Deng, Feng, Xia, Qinghua

“…Dry gel conversion (DGC) technique is first applied in the synthesis of organic–inorganic hybrid aluminosilicate zeolites. By using the DGC method,…”
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Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons by Capano, Lucia S, Sato, Chihiro, Ficulle, Elena, Yu, Anan, Horie, Kanta, Kwon, Ji-Sun, Burbach, Kyle F, Barthélemy, Nicolas R, Fox, Susan G, Karch, Celeste M, Bateman, Randall J, Houlden, Henry, Morimoto, Richard I, Holtzman, David M, Duff, Karen E, Yoo, Andrew S

“…Tau is a microtubule-binding protein expressed in neurons, and the equal ratios between 4-repeat (4R) and 3-repeat (3R) isoforms are maintained in normal adult…”
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Quantitative proteomic analysis of the effects of dietary deprivation of methionine and cystine on A549 xenograft and A549 xenograft‐bearing mouse by Yang, Hao, Zheng, Haoyang, Pan, Yue, Zhang, Weiguo, Yang, Mengjing, Du, Huiling, Yu, Anan, Li, Ping, Chen, Xiaoyan, Xie, Wei, Ren, Kaiming, Zhao, Ying, Wang, Tianjiao, He, Xiaoyan, Zhou, Zhaoli

“…Methionine (Met) and cystine (CySS) are key sulfur donors in cell metabolism and are important nutrients for sustaining tumor growth; however, the molecular…”
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Key Interactions for Clathrin Coat Stability by Böcking, Till, Aguet, François, Rapoport, Iris, Banzhaf, Manuel, Yu, Anan, Zeeh, Jean Christophe, Kirchhausen, Tom

“…Clathrin-coated vesicles are major carriers of vesicular traffic in eukaryotic cells. This endocytic pathway relies on cycles of clathrin coat assembly and…”
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mPEG-PLA/TPGS mixed micelles via intranasal administration improved the bioavailability of lamotrigine in the hippocampus by Yu, Anan, Lv, Jieqiong, Yuan, Fang, Xia, Zihua, Fan, Kaiyan, Chen, Gang, Ren, Jialin, Lin, Cuicui, Wei, Shijie, Yang, Fan

“…This study aimed to develop a novel methoxy poly(ethylene glycol)-poly(lactide) (mPEG-PLA)/D-α-tocopherol polyethylene glycol 1000 succinate (TPGS) mixed…”
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Protein aggregation can inhibit clathrin-mediated endocytosis by chaperone competition by Yu, Anan, Shibata, Yoko, Shah, Bijal, Calamini, Barbara, Lo, Donald C., Morimoto, Richard I.

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The small chemical vacuolin-1 inhibits Ca(2+)-dependent lysosomal exocytosis but not cell resealing by Cerny, Jan, Feng, Yan, Yu, Anan, Miyake, Katsuya, Borgonovo, Barbara, Klumperman, Judith, Meldolesi, Jacopo, McNeil, Paul L, Kirchhausen, Tomas

“…Resealing after wounding, the process of repair following plasma membrane damage, requires exocytosis. Vacuolins are molecules that induce rapid formation of…”
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The small chemical vacuolin-1 inhibits Ca2+-dependent lysosomal exocytosis but not cell resealing by Cerny, Jan, Feng, Yan, Yu, Anan, Miyake, Katsuya, Borgonovo, Barbara, Klumperman, Judith, Meldolesi, Jacopo, McNeil, Paul L, Kirchhausen, Tomas

“…Resealing after wounding, the process of repair following plasma membrane damage, requires exocytosis. Vacuolins are molecules that induce rapid formation of…”
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