Search Results - "Ytterberg, Jimmy A."
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Release of Active Peptidyl Arginine Deiminases by Neutrophils Can Explain Production of Extracellular Citrullinated Autoantigens in Rheumatoid Arthritis Synovial Fluid
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-12-2015)“…Objective In the majority of patients with rheumatoid arthritis (RA), antibodies specifically recognize citrullinated autoantigens that are generated by…”
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Lungs, joints and immunity against citrullinated proteins in rheumatoid arthritis
Published in Nature reviews. Rheumatology (01-11-2014)“…Key Points Autoantibodies against post-translational modified citrullinated proteins, so-called anti-citrullinated protein antibodies (ACPAs), define a…”
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Reducing VEGF-B Signaling Ameliorates Renal Lipotoxicity and Protects against Diabetic Kidney Disease
Published in Cell metabolism (07-03-2017)“…Diabetic kidney disease (DKD) is the most common cause of severe renal disease, and few treatment options are available today that prevent the progressive loss…”
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Optimizing Recombinant Protein Production in the Escherichia coli Periplasm Alleviates Stress
Published in Applied and environmental microbiology (15-06-2018)“…In , many recombinant proteins are produced in the periplasm. To direct these proteins to this compartment, they are equipped with an N-terminal signal…”
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Antibodies to carbamylated α-enolase epitopes in rheumatoid arthritis also bind citrullinated epitopes and are largely indistinct from anti-citrullinated protein antibodies
Published in Arthritis research & therapy (04-05-2016)“…In addition to anti-citrullinated protein antibodies (ACPAs), antibodies targeting carbamylated (i.e., homocitrullinated) proteins (anti-CarP antibodies) have…”
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Protein Profiling of Plastoglobules in Chloroplasts and Chromoplasts. A Surprising Site for Differential Accumulation of Metabolic Enzymes
Published in Plant physiology (Bethesda) (01-03-2006)“…Plastoglobules (PGs) are oval or tubular lipid-rich structures present in all plastid types, but their specific functions are unclear. PGs contain quinones,…”
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Integration of Protein Processing Steps on a Droplet Microfluidics Platform for MALDI-MS Analysis
Published in Analytical chemistry (Washington) (01-03-2010)“…A droplet-based (digital) microfluidics platform has been developed to prepare and purify protein samples for measurement by matrix-assisted laser…”
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IgG Fc galactosylation predicts response to methotrexate in early rheumatoid arthritis
Published in Arthritis research & therapy (09-08-2017)“…Methotrexate (MTX) is the standard first-line therapy in rheumatoid arthritis (RA) with variable clinical efficacy that is difficult to predict. The…”
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Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis
Published in Journal of autoimmunity (01-11-2017)“…Abstract Oxidation-associated malondialdehyde (MDA) modification of proteins can generate immunogenic neo-epitopes that are recognized by autoantibodies. In…”
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Consequences of Membrane Protein Overexpression in Escherichia coli
Published in Molecular & cellular proteomics (01-09-2007)“…Overexpression of membrane proteins is often essential for structural and functional studies, but yields are frequently too low. An understanding of the…”
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Approach for Identifying Human Leukocyte Antigen (HLA)-DR Bound Peptides from Scarce Clinical Samples
Published in Molecular & cellular proteomics (01-09-2016)“…Immune-mediated diseases strongly associating with human leukocyte antigen (HLA) alleles are likely linked to specific antigens. These antigens are presented…”
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In-depth analysis of the thylakoid membrane proteome of Arabidopsis thaliana chloroplasts: new proteins, new functions, and a plastid proteome database
Published in The Plant cell (01-02-2004)“…An extensive analysis of the Arabidopsis thaliana peripheral and integral thylakoid membrane proteome was performed by sequential extractions with salt,…”
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The Oligomeric Stromal Proteome of Arabidopsis thaliana Chloroplasts
Published in Molecular & cellular proteomics (01-01-2006)“…This study presents an analysis of the stromal proteome in its oligomeric state extracted from highly purified chloroplasts of Arabidopsis thaliana . 241…”
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New Functions of the Thylakoid Membrane Proteome of Arabidopsis thaliana Revealed by a Simple, Fast, and Versatile Fractionation Strategy
Published in The Journal of biological chemistry (19-11-2004)“…Identification of membrane proteomes remains challenging. Here, we present a simple, fast, and scalable off-line procedure based on three-phase partitioning…”
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IgG antibodies to cyclic citrullinated peptides exhibit profiles specific in terms of IgG subclasses, Fc-glycans and a fab-Peptide sequence
Published in PloS one (26-11-2014)“…The Fc-glycan profile of IgG1 anti-citrullinated peptide antibodies (ACPA) in rheumatoid arthritis (RA) patients has recently been reported to be different…”
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Consequences of Depletion of the Signal Recognition Particle in Escherichia coli
Published in The Journal of biological chemistry (11-02-2011)“…Thus far, the role of the Escherichia coli signal recognition particle (SRP) has only been studied using targeted approaches. It has been shown for a handful…”
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Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin
Published in Proceedings of the National Academy of Sciences - PNAS (25-11-2008)“…The Gram-negative bacterium Vibrio cholerae is the causative agent of a severe diarrheal disease that afflicts three to five million persons annually, causing…”
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Affinity purification of the tobacco plastid RNA polymerase and in vitro reconstitution of the holoenzyme
Published in The Plant journal : for cell and molecular biology (01-10-2004)“…We affinity-purified the tobacco plastid-encoded plastid RNA polymerase (PEP) complex by the α subunit containing a C-terminal 12 x histidine tag using heparin…”
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Mining proteomic data to expose protein modifications in Methanosarcina mazei strain Gö1
Published in Frontiers in microbiology (2015)“…Proteomic tools identify constituents of complex mixtures, often delivering long lists of identified proteins. The high-throughput methods excel at matching…”
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Natural polymorphisms in Tap2 influence negative selection and CD4∶CD8 lineage commitment in the rat
Published in PLoS genetics (01-02-2014)“…Genetic variation in the major histocompatibility complex (MHC) affects CD4∶CD8 lineage commitment and MHC expression. However, the contribution of specific…”
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