Search Results - "Yowler, Brian"

Botulinum Neurotoxin A Activity Is Dependent upon the Presence of Specific Gangliosides in Neuroblastoma Cells Expressing Synaptotagmin I by Yowler, Brian C., Kensinger, Richard D., Schengrund, Cara-Lynne

“…Botulinum neurotoxin A (BoNT/A) is the deadliest of all known biological substances. Although its toxicity makes BoNT/A a biological warfare threat, its…”
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Botulinum Neurotoxin A Changes Conformation upon Binding to Ganglioside GT1b by Yowler, Brian C, Schengrund, Cara-Lynne

“…In this work, the kinetics of the binding of botulinum neurotoxin A (BoNT/A) to ganglioside GT1b were studied using surface plasmon resonance (SPR). The…”
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Synthesis of Novel, Multivalent Glycodendrimers as Ligands for HIV-1 gp120 by Kensinger, Richard D, Yowler, Brian C, Benesi, Alan J, Schengrund, Cara-Lynne

“…Multivalent neoglycoconjugates are valuable tools for studying carbohydrate−protein interactions. To study the interaction of HIV-1 gp120 with its reported…”
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Disruption of lipid rafts enhances activity of botulinum neurotoxin serotype A by Petro, Kimberly A., Dyer, Maureen A., Yowler, Brian C., Schengrund, Cara-Lynne

“…Botulinum neurotoxin serotype A (BoNT/A), one of seven serotypes of botulinum neurotoxin, is taken up by neurons of the peripheral nervous system. Within the…”
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Glycosphingolipids-sweets for botulinum neurotoxin by Yowler, Brian C, Schengrund, Cara-Lynne

“…A number of viruses, bacteria, and bacterial toxins can only act on cells that express the appropriate glycosphingolipids (GSLs) on the outer surface of their…”
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Oxidation and base-catalyzed elimination of the saccharide portion of GSLs having very different polarities by Yowler, B C, Stoehr, S A, Schengrund, C L

“…Glycosphingolipids (GSLs), present in cell membranes, participate in a variety of biological functions. Although their exact role(s) may not be understood, it…”
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Supporting the democratization of science during a pandemic: genomics Course-based Undergraduate Research Experiences (CUREs) as an effective remote learning strategy by Lopatto, David, Silver Key, S Catherine, Van Stry, Melanie, Siders, Jamie, Leung, Wilson, Sandlin, Katie M, Rele, Chinmay P, Reed, Laura K

“…The initial phase of the COVID-19 pandemic changed the nature of course delivery from largely in-person to exclusively remote, thus disrupting the…”
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Characterization of the interaction of botulinum neurotoxin A with gangliosides by Yowler, Brian Curtis

“…Botulinum neurotoxin (BoNT) is the most potent natural toxin known. While feared as both a food-borne illness and a biological weapon, BoNT/A is used…”
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Properties and crystal structure of a (beta)-barrel folding mutant by Ropson, Ira J, Yowler, Brian C, Dalessio, Paul M, Banaszak, Leonard, Thompson, James

“…A mutant of a beta-barrel protein, rat intestinal fatty acid binding protein, was predicted to be more stable than the wild-type protein due to a novel…”
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Characterization of the interaction of botulinum neurotoxin A with gangliosides by Yowler, Brian Curtis

“…Botulinum neurotoxin (BoNT) is the most potent natural toxin known. While feared as both a food-borne illness and a biological weapon, BoNT/A is used…”
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Properties and Crystal Structure of a β-Barrel Folding Mutant by Ropson, Ira J., Yowler, Brian C., Dalessio, Paula M., Banaszak, Leonard, Thompson, James

“…A mutant of a β-barrel protein, rat intestinal fatty acid binding protein, was predicted to be more stable than the wild-type protein due to a novel hydrogen…”
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