Search Results - "Yow, Tin T."

Effects of an anti-inflammatory VAP-1/SSAO inhibitor, PXS-4728A, on pulmonary neutrophil migration by Schilter, Heidi C, Collison, Adam, Russo, Remo C, Foot, Jonathan S, Yow, Tin T, Vieira, Angelica T, Tavares, Livia D, Mattes, Joerg, Teixeira, Mauro M, Jarolimek, Wolfgang

“…The persistent influx of neutrophils into the lung and subsequent tissue damage are characteristics of COPD, cystic fibrosis and acute lung inflammation…”
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Naringin directly activates inwardly rectifying potassium channels at an overlapping binding site to tertiapin‐Q by Yow, Tin T, Pera, Elena, Absalom, Nathan, Heblinski, Marika, Johnston, Graham AR, Hanrahan, Jane R, Chebib, Mary

“…BACKGROUND G protein‐coupled inwardly rectifying potassium (KIR3) channels are important proteins that regulate numerous physiological processes including…”
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The lysyl oxidase like 2/3 enzymatic inhibitor, PXS‐5153A, reduces crosslinks and ameliorates fibrosis by Schilter, Heidi, Findlay, Alison D., Perryman, Lara, Yow, Tin T., Moses, Joshua, Zahoor, Amna, Turner, Craig I., Deodhar, Mandar, Foot, Jonathan S., Zhou, Wenbin, Greco, Angelique, Joshi, Amar, Rayner, Benjamin, Townsend, Sarah, Buson, Alberto, Jarolimek, Wolfgang

“…Fibrosis is characterized by the excessive deposition of extracellular matrix and crosslinked proteins, in particular collagen and elastin, leading to tissue…”
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PXS-4681A, a potent and selective mechanism-based inhibitor of SSAO/VAP-1 with anti-inflammatory effects in vivo by Foot, Jonathan S, Yow, Tin T, Schilter, Heidi, Buson, Alberto, Deodhar, Mandar, Findlay, Alison D, Guo, Lily, McDonald, Ian A, Turner, Craig I, Zhou, Wenbin, Jarolimek, Wolfgang

“…Semicarbazide-sensitive amine oxidase (SSAO), also known as vascular adhesion protein-1 (VAP-1), is a member of the copper-dependent amine oxidase family that…”
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Hesperidin induces antinociceptive effect in mice and its aglicone, hesperetin, binds to μ-opioid receptor and inhibits GIRK1/2 currents by Loscalzo, Leonardo M., Yow, Tin T., Wasowski, Cristina, Chebib, Mary, Marder, Mariel

“…This paper extended the evaluation of the depressant and antinociceptive activities of hesperidin in order to determine its effectiveness by the…”
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Hesperidin induces antinociceptive effect in mice and its aglycone, hesperetin, binds to μ-opioid receptor and inhibits GIRK1/2 currents by Loscalzo, Leonardo M, Yow, Tin T, Wasowski, Cristina, Chebib, Mary, Marder, Mariel

“…This paper extended the evaluation of the depressant and antinociceptive activities of hesperidin in order to determine its effectiveness by the…”
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