Search Results - "Yovo, Christian"

DPYSL2/CRMP2 isoform B knockout in human iPSC-derived glutamatergic neurons confirms its role in mTOR signaling and neurodevelopmental disorders by Feuer, Kyra L., Peng, Xi, Yovo, Christian K., Avramopoulos, Dimitrios

“…The DPYSL2/CRMP2 gene encodes a microtubule-stabilizing protein crucial for neurogenesis and is associated with numerous psychiatric and neurodegenerative…”
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CRISPR Del/Rei: a simple, flexible, and efficient pipeline for scarless genome editing by Feuer, Kyra L., Wahbeh, Marah H., Yovo, Christian, Rabie, Eman, Lam, Anh-Thu N., Abdollahi, Sara, Young, Lindsay J., Rike, Bailey, Umamageswaran, Akul, Avramopoulos, Dimitrios

“…Scarless genome editing of induced pluripotent stem cells (iPSCs) is crucial for the precise modeling of genetic disease. Here we present CRISPR Del/Rei, a…”
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A functional schizophrenia-associated genetic variant near the TSNARE1 and ADGRB1 genes by Wahbeh, Marah H., Boyd, Rachel J., Yovo, Christian, Rike, Bailey, McCallion, Andrew S., Avramopoulos, Dimitrios

“…Recent collaborative genome-wide association studies (GWAS) have identified >200 independent loci contributing to risk for schizophrenia (SCZ). The genes…”
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A Missense Variant in CASKIN1's Proline-Rich Region Segregates with Psychosis in a Three-Generation Family by Wahbeh, Marah H, Peng, Xi, Bacharaki, Sofia, Hatzimanolis, Alexandros, Dimitrakopoulos, Stefanos, Wohler, Elizabeth, Yang, Xue, Yovo, Christian, Maher, Brady J, Sobreira, Nara, Stefanis, Nikos C, Avramopoulos, Dimitrios

“…The polygenic nature of schizophrenia (SCZ) implicates many variants in disease development. Rare variants of high penetrance have been shown to contribute to…”
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