A rare presentation of OEIS complex in a spontaneous dizygotic twin pregnancy: A case report and literature review

OEIS complex is a rare congenital malformation characterized by the presence of omphalocele, bladder exstrophy, anal imperforation, and spina bifida, with an unclear etiology thought to be multifactorial and heterogeneous. We report a case of OEIS complex in a spontaneous dizygotic twin pregnancy in...

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Bibliographic Details
Published in:	Radiology case reports Vol. 20; no. 1; pp. 797 - 800
Main Authors:	Rejeb, Oumayma Ben, Abid, Skander, Abdelmoula, Ghada, Youssef, Salma Ben, Boughizane, Sassi
Format:	Journal Article
Language:	English
Published:	Elsevier Inc 01-01-2025 Elsevier
Subjects:	Bladder exstrophy Fetal malformations Imperforate anus OEIS complex omphalocele Prenatal diagnosis Spina bifida Imperforate anus Spina bifida Fetal malformations Prenatal diagnosis OEIS complex omphalocele Bladder exstrophy
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Summary:	OEIS complex is a rare congenital malformation characterized by the presence of omphalocele, bladder exstrophy, anal imperforation, and spina bifida, with an unclear etiology thought to be multifactorial and heterogeneous. We report a case of OEIS complex in a spontaneous dizygotic twin pregnancy involving a 29-year-old gravida 2, para 1 woman. The condition was first suspected at 22 weeks of gestation during a detailed ultrasound, which revealed characteristic abnormalities, and was later confirmed by magnetic resonance imaging (MRI) showing omphalocele, bladder exstrophy, and spinal malformations. This case emphasizes the importance of prenatal imaging, particularly ultrasound and MRI, in the early detection of OEIS complex, as accurate prenatal diagnosis is crucial for effective counseling, optimizing perinatal management, and planning for postnatal reconstructive surgery.
ISSN:	1930-0433 1930-0433
DOI:	10.1016/j.radcr.2024.10.088