Search Results - "Youssef, Nourhan"

Inflammatory Th1 and Th17 in the Intestine Are Each Driven by Functionally Specialized Dendritic Cells with Distinct Requirements for MyD88 by Liang, Jie, Huang, Hsin-I, Benzatti, Fernanda P., Karlsson, Amelia B., Zhang, Junyi J., Youssef, Nourhan, Ma, Averil, Hale, Laura P., Hammer, Gianna E.

“…Normal dynamics between microbiota and dendritic cells (DCs) support modest numbers of T cells, yet these do not cause inflammation. The DCs that induce…”
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Irgm1-deficiency leads to myeloid dysfunction in colon lamina propria and susceptibility to the intestinal pathogen Citrobacter rodentium by Taylor, Gregory A, Huang, Hsin-I, Fee, Brian E, Youssef, Nourhan, Jewell, Mark L, Cantillana, Viviana, Schoenborn, Alexi A, Rogala, Allison R, Buckley, Anne F, Feng, Carl G, Vallance, Bruce A, Gulati, Ajay S, Hammer, Gianna E

“…IRGM and its mouse orthologue Irgm1 are dynamin-like proteins that regulate vesicular remodeling, intracellular microbial killing, and pathogen immunity. IRGM…”
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Th17 Immunity in the Colon Is Controlled by Two Novel Subsets of Colon-Specific Mononuclear Phagocytes by Huang, Hsin-I, Jewell, Mark L, Youssef, Nourhan, Huang, Min-Nung, Hauser, Elizabeth R, Fee, Brian E, Rudemiller, Nathan P, Privratsky, Jamie R, Zhang, Junyi J, Reyes, Estefany Y, Wang, Donghai, Taylor, Gregory A, Gunn, Michael D, Ko, Dennis C, Cook, Donald N, Chandramohan, Vidyalakshmi, Crowley, Steven D, Hammer, Gianna Elena

“…Intestinal immunity is coordinated by specialized mononuclear phagocyte populations, constituted by a diversity of cell subsets. Although the cell subsets…”
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Unleashing the mysterious link between COVID-19 and a famous childhood vasculitis: Kawasaki disease by AbdelMassih, Antoine Fakhry, AbdelAzeam, Aisha Said, Ayad, Aya, Kamel, Aya Yasser, Khalil, Ayah, Kotb, Basma, Waheed, Dina, Menshawey, Esraa, Sefein, Fady, Taha, Farah, Ismail, Habiba-Allah, Osman, Ibrahim, Iskander, John, El Wakil, Lama, Rashad, Lara, Arsanyous, Mariem Badr, El Shershaby, Meryam, Mansour, Mina, Ashraf, Mirette, Hafez, Nada, Abuzeid, Nadeen Mohamed, AbdElSalam, Noheir Mahmoud-Nashaat, Hafez, Nouran Gamal, Youssef, Nourhan, Hozaien, Rafeef, Saeed, Rana, Kamel, Dina, AbdelHameed, Manal Ahmed, Ali, Salma

“…Background Coronavirus disease 2019 (COVID-19) emerged as a small outbreak in Wuhan rapidly progressing into the deadliest pandemic since the Spanish flu of…”
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Th17 immunity in the colon is controlled by two novel subsets of colon-specific mononuclear phagocytes by Huang, Hsin-I, Youssef, Nourhan, Jewell, Mark, Huang, Min-Nung, Hammer, Gianna

“…Abstract Immune responses in the intestine are coordinated by specialized populations of mononuclear phagocytes. Although the functions of intestine-resident…”
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The Ubiquitin-Modifying Enzyme A20 Terminates C-Type Lectin Receptor Signals and Is a Suppressor of Host Defense against Systemic Fungal Infection by Liang, Jie, Zhang, Junyi J, Huang, Hsin-I, Kanayama, Masashi, Youssef, Nourhan, Jin, Yingai J, Reyes, Estefany Y, Abram, Clare L, Yang, Shigao, Lowell, Clifford A, Wang, Donghai, Shao, Ling, Shinohara, Mari L, Zhang, Jennifer Y, Hammer, Gianna Elena

“…C-type lectin receptors (CLRs) play key roles in antifungal defense. CLR-induced NF-κB is central to CLR functions in immunity, and thus, molecules that…”
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Possible molecular and paracrine involvement underlying the pathogenesis of COVID-19 cardiovascular complications by AbdelMassih, Antoine Fakhry, Ramzy, David, Nathan, Lauren, Aziz, Silvia, Ashraf, Mirette, Youssef, Nourhan Hatem, Hafez, Nouran, Saeed, Rana, Agha, Hala

“…Coronavirus disease 2019 (COVID-19) has been declared a pandemic on 11 March 2020 by the WHO. Despite being mainly a respiratory virus, cardiac complications…”
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A multicenter consensus: A role of furin in the endothelial tropism in obese patients with COVID-19 infection by AbdelMassih, Antoine Fakhry, Ye, Jianping, Kamel, Aya, Mishriky, Fady, Ismail, Habiba-Allah, Ragab, Heba Amin, El Qadi, Layla, Malak, Lauris, Abdu, Mariam, El-Husseiny, Miral, Ashraf, Mirette, Hafez, Nada, AlShehry, Nada, El-Husseiny, Nadine, AbdelRaouf, Nora, Shebl, Noura, Hafez, Nouran, Youssef, Nourhan, Afdal, Peter, Hozaien, Rafeef, Menshawey, Rahma, Saeed, Rana, Fouda, Raghda

“…Furin, a cleavage enzyme, is increasingly recognized in the pathogenesis of metabolic syndrome. Its cleavage action is an essential activation step for the…”
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Is OSA risk proportional to BMI or parentally mediated? A questionnaire-based study in a cohort of Egyptian children by AbdelMassih, Antoine, ElKhashab, Khaled, Ismail, Habiba-Allah, Ashraf, Mirette, Hafez, Nada, Hafez, Nouran, Youssef, Nourhan Hatem, Saeed, Rana

“…There is an increased body of evidence that Obstructive Sleep apnea (OSA) in obese patients has familial tendencies. This familial predilection might be…”
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Peroxisome proliferator-activated receptor agonists and reversal of vascular degeneration through DNA repair, a step toward drug-induced regenerative medicine by Afdal, Peter, Ismail, Habiba-Allah, Ashraf, Mirette, Hafez, Nada, Nasry, Nardine, Hafez, Nouran, Youssef, Nourhan, Samy, Nourhan, Saeed, Rana, AbdelMassih, Antoine Fakhry

“…Endothelial dysfunction with subsequent degeneration and vasoocclusive remodeling is the hallmark of many cardiovascular disorders including pulmonary vascular…”
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The microvascular hypothesis underlying neurologic manifestations of long COVID-19 and possible therapeutic strategies

“…With the ongoing distribution of the coronavirus disease (COVID) vaccines, the pandemic of our age is ending, leaving the world to deal with its…”
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Single cell sequencing unraveling genetic basis of severe COVID19 in obesity by AbdelMassih, Antoine Fakhry, Fouda, Raghda, Kamel, Aya, Mishriky, Fady, Ismail, Habiba-Allah, El Qadi, Layla, Malak, Lauris, Mohamed, Maram, Arsanyous, Mariem, Hazem, Maysa, El-Husseiny, Miral, Ashraf, Mirette, Hafez, Nada, AlShehry, Nada, El-Husseiny, Nadine, AbdelRaouf, Nora, Shebl, Noura, Hafez, Nouran, Youssef, Nourhan, Afdal, Peter, Hozaien, Rafeef, Menshawey, Rahma, Saeed, Rana, Yasser, Reem, Hesham, Shereen, Zakarriah, Wesam, Khattab, Shahenda, Elammary, Yasmine, Ye, Jianping

“…COVID-19 has shown a substantial variation in the rate and severity by which it impacts different demographic groups. Specifically, it has shown a predilection…”
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Is it infection or rather vascular inflammation? Game-changer insights and recommendations from patterns of multi-organ involvement and affected subgroups in COVID-19 by AbdelMassih, Antoine Fakhry, Kamel, Aya, Mishriky, Fady, Ismail, Habiba-Allah, El Qadi, Layla, Malak, Lauris, El-Husseiny, Miral, Ashraf, Mirette, Hafez, Nada, AlShehry, Nada, El-Husseiny, Nadine, AbdelRaouf, Nora, Shebl, Noura, Hafez, Nouran, Youssef, Nourhan, Afdal, Peter, Hozaien, Rafeef, Menshawey, Rahma, Saeed, Rana, Fouda, Raghda

“…Coronavirus disease 2019 (COVID-19) is a serious illness that has rapidly spread throughout the globe. The seriousness of complications puts significant…”
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The role of miRNAs in viral myocarditis, and its possible implication in induction of mRNA-based COVID-19 vaccines-induced myocarditis by AbdelMassih, Antoine, Agha, Hala, El-Saiedi, Sonia, El-Sisi, Amal, El Shershaby, Meryam, Gaber, Hanya, Ismail, Habiba-Allah, El-Husseiny, Nadine, Amin, Abeer Reda, ElBoraie, Aly, Ayad, Aya, Menshawey, Esraa, Sefein, Fady, Osman, Ibrahim Ihab, Moursi, Mai, Hanafy, Maram, Abdelaziz, Mariam Sherif, Arsanyous, Mariem Badr, Khaled-Ibn-El-Walid, Mariam, Tawfik, Marwa Gamal, Habib, Menna, Mansour, Mina Ehab, Ashraf, Mirette, Khattab, Mohamed Ayman, Alshehry, Nada, Hafez, Nada, ElDeeb, Naheel Essam, Ashraf, Nirvana, Khalil, Noha, AbdElSalam, Noheir Ismail, Shebl, Noura, Hafez, Nouran Gamal Ali, Youssef, Nourhan Hatem, Bahnan, Odette, Ismail, Passant, Kelada, Peter, Menshawey, Rahma, Saeed, Rana, Husseiny, Reem Jalal, Yasser, Reem, Sharaf, Safa, Adel, Veronia, Naeem, Youstina, Nicola, Youstina Nagy Farid, Kamel, Aya, Hozaien, Rafeef, Fouda, Raghda

“…Background Several reports of unheeded complications secondary to the current mass international rollout of SARS-COV-2 vaccines, one of which is myocarditis…”
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Inflammatory Th1 and Th17 cells in small intestine are each driven by functionally-specialized dendritic cells with distinct requirements for MyD88 by Liang, Jie, Huang, Hsin-I, Benzatti, Fernanda P., Karlsson, Amelia B., Zhang, Junyi J., Youssef, Nourhan, Ma, Averil, Hale, Laura P., Hammer, Gianna E.

“…Normal dynamics between microbiota and dendritic cells (DCs) support modest numbers of T cells, yet these do not cause inflammation. The DCs that induce…”
Get full text