Search Results - "Youqiang, Ke"

The cancer-promoting gene fatty acid-binding protein 5 (FABP5) is epigenetically regulated during human prostate carcinogenesis by Kawaguchi, Koichiro, Kinameri, Ayumi, Suzuki, Shunsuke, Senga, Shogo, Ke, Youqiang, Fujii, Hiroshi

“…FABPs (fatty-acid-binding proteins) are a family of low-molecular-mass intracellular lipid-binding proteins consisting of ten isoforms. FABPs are involved in…”
Get more information

High expression of Fatty Acid‐Binding Protein 5 promotes cell growth and metastatic potential of colorectal cancer cells by Kawaguchi, Koichiro, Senga, Shogo, Kubota, Chiaki, Kawamura, Yuki, Ke, Youqiang, Fujii, Hiroshi

“…Fatty acid‐binding proteins (FABPs) are responsible for binding and storing hydrophobic ligands such as long‐chain fatty acids, and for transporting these…”
Get full text

Increased Id-1 expression is significantly associated with poor survival of patients with prostate cancer by Forootan, Shiva S., MD, PhD, Wong, Yong-Chuan, PhD, Dodson, Andrew, BSc, MSc, Wang, Xianghong, PhD, Lin, Ke, PhD, Smith, Paul H., PhD, Foster, Christopher S., MD, PhD, DSc, FASCP, FRCPath, Ke, Youqiang, DVM, PhD

“…Summary The levels of Id-1 (inhibitor of DNA binding or inhibitor of cell differentiation) expression in a series of prostate cell lines and in an archival set…”
Get full text

siRNA knockdown of ribosomal protein gene RPL19 abrogates the aggressive phenotype of human prostate cancer by Bee, Alix, Brewer, Daniel, Beesley, Carol, Dodson, Andrew, Forootan, Shiva, Dickinson, Timothy, Gerard, Patricia, Lane, Brian, Yao, Sheng, Cooper, Colin S, Djamgoz, Mustafa B A, Gosden, Christine M, Ke, Youqiang, Foster, Christopher S

“…We provide novel functional data that posttranscriptional silencing of gene RPL19 using RNAi not only abrogates the malignant phenotype of PC-3M prostate…”
Get full text

Letter to the Editor: Perspectives on mRNA Vaccine Development for Cancer by Ke, Youqiang

“…Recently, messenger ribonucleic acid (mRNA) vaccine research and development became a hotspot in the field of prevention and treatment of Corona Virus Disease…”
Get more information

Heat shock protein expression independently predicts clinical outcome in prostate cancer by CORNFORD, Philip A, DODSON, Andrew R, PARSONS, Keith F, DESMOND, Anthony D, WOOLFENDEN, Alan, FORDHAM, Mark, NEOPTOLEMOS, John P, YOUQIANG KE, FOSTER, Christopher S

“…Heat shock proteins (hsps) occupy a central role in the regulation of intracellular homeostasis, and differential expression of individual hsps occurs in a…”
Get full text

Prognostic significance of osteopontin expression in human prostate cancer by Forootan, Shiva S., Foster, Christopher S., Aachi, Vijay R., Adamson, Janet, Smith, Paul H., Lin, Ke, Ke, Youqiang

“…To test the hypothesis that expression of osteopontin (OPN), an integrin‐binding glycoprotein, can independently predict the potential aggressiveness of…”
Get full text

Increased Expression of Id Family Proteins in Small Cell Lung Cancer and its Prognostic Significance by KAMALIAN, Laleh, GOSNEY, John R, FOROOTAN, Shiva S, FOSTER, Christopher S, BAO, Zheng Z, BEESLEY, Carol, YOUQIANG KE

“…Purpose: To study the molecular pathology of human small cell lung cancer (SCLC), molecular biology approaches were used to identify genes involved in…”
Get full text

High-level expression of cutaneous fatty acid-binding protein in prostatic carcinomas and its effect on tumorigenicity by ADAMSON, Janet, MORGAN, Elwin A, BEESLEY, Carol, YONGQIANG MEI, FOSTER, Christopher S, FUJII, Hiroshi, RUDLAND, Philip S, SMITH, Paul H, YOUQIANG KE

“…The expression of cutaneous fatty acid-binding protein (C-FABP) in prostate tissues was examined by immunohistochemistry. Among the 76 cases, all seven (100%)…”
Get full text

Expression of cutaneous fatty acid-binding protein (C-FABP) in prostate cancer : Potential prognostic marker and target for tumourigenicity-suppression by MORGAN, Elwin A, FOROOTAN, Shiva S, ADAMSON, Janet, FOSTER, Christopher S, FUJII, Hiroshi, IGARASHI, Michihiro, BEESLEY, Carol, SMITH, Paul H, YOUQIANG KE

“…C-FABP or E-FABP is a metastasis inducing gene over expressed in human prostate carcinomas. To study its prognostic significance, an archival set of prostate…”
Get full text

Atelocollagen-delivered siRNA targeting the FABP5 gene as an experimental therapy for prostate cancer in mouse xenografts by FOROOTAN, Shiva S, BAO, Zheng Z, FOROOTAN, Farzad S, KAMALIAN, Laleh, YU ZHANG, BEE, Alix, FOSTER, Christopher S, YOUQIANG KE

“…The gene FABP5 encodes cutaneous fatty acid binding protein (C-FABP) that is up-regulated in prostate cancer where it acts as a putative oncogene. To test the…”
Get full text

Suppressing tumourigenicity of prostate cancer cells by inhibiting osteopontin expression by YU ZHANG, FOROOTAN, Shiva S, KAMALIAN, Laleh, BAO, Zheng Z, MALKI, Mohammed I, FOSTER, Christopher S, YOUQIANG KE

“…Expression of osteopontin (OPN) is increased in prostate cancer cells. The possibility of utilising the increased OPN as a target to suppress the…”
Get full text

Inhibition of tumourigenicity of small cell lung cancer cells by suppressing Id3 expression by KAMALIAN, Laleh, FOROOTAN, Shiva S, BAO, Zheng Z, YU ZHANG, GOSNEY, John R, FOSTER, Christopher S, YOUQIANG KE

“…Id3 is over-expressed in small cell lung cancer (SCLC). To test whether the tumourigenicity of SCLC cells can be inhibited by suppressing Id3 expression, we…”
Get full text

Tazarotene-Induced Gene 1 (TIG1) Expression in Prostate Carcinomas and Its Relationship to Tumorigenicity by Jing, Chun, El-Ghany, Manal Abd, Beesley, Carol, Foster, Christopher S., Rudland, Philip S., Smith, Paul, Ke, Youqiang

“…Background: Prostate cancer is the most common noncutaneous male cancer and one of the least understood malignant diseases. Identifying key genetic factors…”
Get full text

Tissue microarray of head and neck squamous carcinoma : validation of the methodology for the study of cutaneous fatty acid-binding protein, vascular endothelial growth factor, involucrin and Ki-67 by GOMAA, Wafaey, YOUQIANG KE, FUJII, Hiroshi, HELLIWELL, Timothy

“…Tissue microarrays allow the simultaneous analysis of many tumours using small-diameter cores sampled from larger blocks of tissue, but may be limited by…”
Get full text

Primer: tissue fixation and preservation for optimal molecular analysis of urologic tissues by Foster, Christopher S, Gosden, Christine M, Ke, Youqiang Q

“…Appreciation of the different methods of tissue handling is a prerequisite to obtaining accurate and biologically relevant tissue-based information. When a…”
Get full text

Identification of the messenger RNA for human cutaneous fatty acid-binding protein as a metastasis inducer by CHUN JING, BEESLEY, C, FOSTER, C. S, RUDLAND, P. S, FUJII, H, ONO, T, HAIJUAN CHEN, SMITH, P. H, YOUQIANG KE

“…Using our recently developed systematic differential display and complete comparison of gene expression approaches combined with other methods, we have…”
Get full text

Human cutaneous fatty acid-binding protein induces metastasis by up-regulating the expression of vascular endothelial growth factor gene in rat Rama 37 model cells by CHUN JING, BEESLEY, Carol, FOSTER, Christopher S, HAIJUAN CHEN, RUDLAND, Philip S, WEST, David C, FUJII, Hiroshi, SMITH, Paul H, YOUQIANG KE

“…Human cutaneous fatty acid-binding protein (C-FABP) gene is capable of inducing the metastatic phenotype when overexpressed in nonmetastatic rat Rama 37 cells…”
Get full text

SBFI26 induces triple‐negative breast cancer cells ferroptosis via lipid peroxidation by He, Gang, Zhang, Yiyuan, Feng, Yanjiao, Chen, Tangcong, Liu, Mei, Zeng, Yue, Yin, Xiaojing, Qu, Shaokui, Huang, Lifen, Ke, Youqiang, Liang, Li, Yan, Jun, Liu, Wei

“…SBFI26, an inhibitor of FABP5, has been shown to suppress the proliferation and metastasis of tumour cells. However, the underlying mechanism by which SBFI26…”
Get full text

Molecular mechanisms on how FABP5 inhibitors promote apoptosis‐induction sensitivity of prostate cancer cells by Zhang, Jiacheng, He, Gang, Jin, Xi, Alenezi, Bandar T., Naeem, Abdulghani A., Abdulsamad, Saud A., Ke, Youqiang

“…Previous work showed that FABP5 inhibitors suppressed the malignant progression of prostate cancer cells, and this suppression might be achieved partially by…”
Get full text