Search Results - "Yount, Ralph G"

Molecular dynamics analysis of structural factors influencing back door pi release in myosin by Lawson, J David, Pate, Edward, Rayment, Ivan, Yount, Ralph G

“…The back door has been proposed to be an exit pathway from the myosin active site for phosphate (P(i)) generated by adenosine 5'-triphosphate hydrolysis. We…”
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Closing of the Nucleotide Pocket of Kinesin-Family Motors upon Binding to Microtubules by Naber, Nariman, Minehardt, Todd J., Rice, Sarah, Chen, Xiaoru, Grammer, Jean, Matuska, Marija, Vale, Ronald D., Kollman, Peter A., Car, Roberto, Yount, Ralph G., Cooke, Roger, Pate, Edward

“…We have used adenosine diphosphate analogs containing electron paramagnetic resonance (EPR) spin moieties and EPR spectroscopy to show that the…”
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Conformational Changes between the Active-Site and Regulatory Light Chain of Myosin as Determined by Luminescence Resonance Energy Transfer: The Effect of Nucleotides and Actin by Xiao, Ming, Li, Handong, Snyder, Gregory E., Cooke, Roger, Yount, Ralph G., Selvin, Paul R.

“…Myosin is thought to generate movement of actin filaments via a conformational change between its lightchain domain and its catalytic domain that is driven by…”
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A Novel Restricted Photoaffinity Spin-Labeled Non-Nucleoside ATP Analogue as a Covalently Attached Reporter Group of the Active Site of Myosin Subfragment 1 by Chen, Xiaoru, Grammer, Jean, Lawson, J. David, Cooke, Roger, Pate, Edward, Yount, Ralph G

“…The photoaffinity spin-labeled non-nucleoside ATP analogue,…”
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Raman Difference Spectroscopic Studies of the Myosin S1·MgADP·Vanadate Complex by Deng, Hua, Wang, Jianghua, Callender, Robert H, Grammer, Jean C, Yount, Ralph G

“…The Raman spectra of the nonbridging V O bonds in the myosin S1·MgADP·Vi complex, often believed to be a transition-state analogue for the phosphotransfer…”
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Chemistry and Mechanism of Vanadate-Promoted Photooxidative Cleavage of Myosin by Grammer, Jean C, Loo, Joseph A, Edmonds, Charles G, Cremo, Christine R, Yount, Ralph G

“…Irradiation of the stable myosin subfragment 1(S1)·MgADP·orthovanadate (Vi) complex results in oxidation of an active site serine (Ser-180) to a serine…”
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Fingerprint patterns from laser-induced Azido photochemistry of spin-labeled photoaffinity ATP analogs in matrix-assisted laser desorption/ionization mass spectrometry by Chen, Xiaoru, Siems, William F, Asbury, G.Reid, Yount, Ralph G

“…The photochemical reaction of azide derivatives induced by ultraviolet (UV) laser in matrix-assisted laser desorption/ionization mass spectrometry (MALDI) is…”
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X-ray Structures of the Dictyostelium discoideumMyosin Motor Domain with Six Non-nucleotide Analogs by Gulick, Andrew M., Bauer, Cary B., Thoden, James B., Pate, Ed, Yount, Ralph G., Rayment, Ivan

“…The three-dimensional structures of the truncated myosin head from Dictyostelium discoideum myosin II complexed with dinitrophenylaminoethyl-,…”
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Synthesis and Characterization of Novel Spin-Labeled Photoaffinity Nonnucleoside Analogues of ATP as Structural and EPR Probes for Myosin by Chen, Xiaoru, Grammer, Jean, Cooke, Roger, Pate, Edward, Yount, Ralph G

“…Two new spin-labeled photoreactive nonnucleoside ATP analogues, 1-(4-azido-2-nitrophenyl)amino-3-(1-oxyl-2,2,5,5-tetramethylpyrrolidinyl-3-carbamido)-2-propyl…”
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Imidodiphosphate and Pyrophosphate: Possible Biological Significance of Similar Structures by Larsen, Marlin, Willett, Roger, Yount, Ralph G.

“…The structure of sodium imidodiphosphate has been determined by single crystal x-ray diffraction. The P-N-P bond angle (127.2°) and P-N bond distance (1.68…”
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Photoaffinity labeling of skeletal myosin with 2-azidoadenosine triphosphate by Grammer, Jean C, Kuwayama, Hideto, Yount, Ralph G

“…The purine binding site of ATP on skeletal muscle myosin has been photoaffinity labeled with 2-azidoadenosine diphosphate (2-N3ADP). 2-N3ADP was stably trapped…”
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Synthesis of a spin-labeled photoaffinity ATP analogue, and its use to specifically photolabel myosin cross-bridges in skeletal muscle fibers by Wang, D, Luo, Y, Cooke, R, Grammer, J, Pate, E, Yount, R G

“…A spin-labeled photoaffinity ATP analogue 3'(2')-O-[4-[4-oxo-(4-amido-2,2,6,6-tetramethyl-piperidino-1-oxyl)]-benz oyl]benzoyl adenosine 5'-triphosphate…”
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Photoaffinity ADP analogs as covalently attached reporter groups of the active site of myosin subfragment 1 by Luo, Yin, Wang, Donald, Cremo, Christine R, Pate, Edward, Cooke, Roger, Yount, Ralph G

“…The enzymatic properties of rabbit skeletal myosin subfragment 1 (S1) have been determined after photoaffinity labeling the active site with two ADP analogs…”
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Serine-324 of myosin's heavy chain is photoaffinity-labeled by 3'(2')-O-(4-benzoylbenzoyl)adenosine triphosphate by Mahmood, Riaz, Elzinga, Marshall, Yount, Ralph G

“…A portion of the active site of rabbit skeletal myosin near the ribose ring of ATP can be labeled by the photoaffinity analogue…”
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UV-induced vanadate-dependent modification and cleavage of skeletal myosin subfragment 1 heavy chain. 1. Evidence for active site modification by Grammer, Jean C, Cremo, Christine R, Yount, Ralph G

“…Ultraviolet irradiation above 300 nm of the stable MgADP-orthovanadate (Vi)-myosin subfragment 1 (S1) complex resulted in covalent modification of the S1 and…”
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Photochemical Mapping of the Active Site of Myosin [and Discussion] by Yount, Ralph G., Cremo, Christine R., Grammer, Jean C., Kerwin, Bruce A., Goody, R. S., Mitchison, T. J., Trentham, D. R., Dutton, P. L.

“…The active sites of myosin from skeletal, smooth and scallop muscle have been partly characterized by use of a series of photoreactive analogues of ATP…”
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The essential light chains constitute part of the active site of smooth muscle myosin by Okamoto, Yoh, Sekine, Takamitsu, Grammer, Jean, Yount, Ralph G

“…Myosin, a major contractile protein, characteristically possesses a long coiled-coil alpha-helical tail and two heads. Each head contains both an actin binding…”
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Photoaffinity labeling of scallop myosin with 2-[(4-azido-2-nitrophenyl)amino]ethyl diphosphate: identification of an active site arginine analogous to tryptophan-130 in skeletal muscle myosin by Kerwin, Bruce A, Yount, Ralph G

“…The ADP photoaffinity analogue 2-[(4-azido-2-nitrophenyl)amino]ethyl diphosphate (NANDP) was used to photolabel the ATP binding site of scallop myosin…”
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Photolabeling Evidence for Calcium-Induced Conformational Changes at the ATP Binding Site of Scallop Myosin by Kerwin, Bruce A., Yount, Ralph G.

“…A change in the conformation of the active site of scallop myosin under the influence of regulatory amounts of Ca2+has been identified by use of the ADP…”
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Stability and photochemical properties of vanadate-trapped nucleotide complexes of gizzard myosin in the 6S and 10S conformations: identification of an active-site serine by Cole, Douglas G, Yount, Ralph G

“…The properties of divalent metal.ADP.vanadate (V(i)) complexes of the 6S extended and 10S folded conformations of gizzard myosin before and after UV…”
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