Search Results - "Youngs, Jonathan"

Can the courts force the doctor's hand?: St George's Healthcare NHS Trust v P [2015] EWCOP 42 by Youngs, Jonathan C W

“…In the recent case of 'Re P', Newton J ordered and directed that renal replacement therapy (RRT) continue for a patient who lacked capacity. This was…”
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An unusual presentation of neutropenic enterocolitis (typhlitis) by Youngs, Jonathan, Dr, Suarez, Cristina, PhD, Koh, Mickey B C, FRCPath

“…Neutropenic enterocolitis is a potentially life-threatening condition of the lower gastrointestinal tract (typically the caecum, in which it is termed…”
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Safety and Efficacy of Intermittent High-Dose Liposomal Amphotericin B Antifungal Prophylaxis in Haemato-Oncology: An Eight-Year Single-Centre Experience and Review of the Literature by Youngs, Jonathan, Low, Jen Mae, Whitney, Laura, Logan, Clare, Chase, Janice, Yau, Ting, Klammer, Matthias, Koh, Mickey, Bicanic, Tihana

“…Triazoles remain first-line agents for antifungal prophylaxis in high-risk haemato-oncology patients, but their use is increasingly contraindicated due to…”
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A prospective study evaluating the impact of cartridge-based nucleic acid amplification test (CBNAAT) on the management of tuberculosis in a low-resource high-burden Indian rural setting by Youngs, Jonathan, Patil, Sushil, Jain, Yogesh

“…Background: The cartridge-based nucleic acid amplification test (CBNAAT) Xpert MTB/RIF is more sensitive than smear microscopy for the diagnosis of…”
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Evaluation of perturbed iron-homeostasis in a prospective cohort of patients with COVID-19 by Frost, Joe N, Hamilton, Fergus, Arnold, David, Elvers, Karen T, Shah, Akshay, Armitage, Andrew E, Milne, Alice, McKernon, Jorgen, Attwood, Marie, Chen, Yi-Ling, Xue, Luzheng, Youngs, Jonathan, Provine, Nicholas M, Bicanic, Tihana, Klenerman, Paul, Drakesmith, Hal, Ghazal, Peter

“…Marked reductions in serum iron concentrations are commonly induced during the acute phase of infection. This phenomenon, termed hypoferremia of inflammation,…”
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Infections in the immunocompromised host: secondary immunodeficiency disorders by Youngs, Jonathan, Arnold, Amber

“…The immunocompetent defence against infection comprises a multifaceted and coordinated armoury of physical barriers, and innate and adaptive immunity. Certain…”
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Improving antibiotic stewardship in COVID-19: Bacterial co-infection is less common than with influenza by Youngs, Jonathan, Wyncoll, Duncan, Hopkins, Philip, Arnold, Amber, Ball, Jonathan, Bicanic, Tihana

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Ethical implications of HIV self-testing by Youngs, Jonathan, Hooper, Carwyn

“…In April 2015, the first legally approved HIV self-testing kit went on sale in the UK—except Northern Ireland where they remain illegal. These tests allow…”
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HIV and the right not to know by Youngs, Jonathan, Simmonds, Joshua

“…It is a tenet of the prevailing ethic in medicine that competent adults have the ‘right to know’ information necessary to make informed decisions about their…”
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A blood atlas of COVID-19 defines hallmarks of disease severity and specificity by Ai, Zhichao, Ainsworth, Mark, Arancibia-Cárcamo, Carolina V., Attar, Moustafa, Baillie, J. Kenneth, Bashford-Rogers, Rachael, Bicanic, Tihana, Bowness, Paul, Brent, Andrew, Buck, David, Camara, Susana, Clutterbuck, Elizabeth A., Coles, Mark, Conlon, Christopher P., Cribbs, Adam P., Curion, Fabiola, Davenport, Emma E., Davidson, Neil, Davis, Simon, Dendrou, Calliope A., Dequaire, Julie, Docker, James, Dold, Christina, Downes, Damien, Drakesmith, Hal, Dunachie, Susanna J., Espinosa, Alexis, Felle, Sally, Fernandez Mendoza, Maria, Forrow, Aden, Frater, John, Fries, Anastasia, Garner, Lucy C., Godfrey, Leila, Gomez Vazquez, Maria, Green, Angie, Harper, Hong, Heilig, Raphael, Hester, Svenja, Hill, Jennifer, Hinds, Charles, Hird, Clare, Hutton, Paula, Jainarayanan, Ashwin, Jansen, Kathrin, Jones, Elizabeth, Klenerman, Paul, Knight, Julian C., Kumar Sharma, Piyush, Kurupati, Prathiba, Kwok, Andrew, Lee, Angela, Lonie, Lorne, Luo, Jian, Marsden, Brian, Martinez, Jose, Matthews, Philippa C., Mazurczyk, Michalina, McGowan, Simon, Mi, Yuxin, Montadon, Ruddy, O'Brien, Darragh P., Ogg, Graham, Overend, Lauren, Pereira Pinho, Mariana, Perez, Elena, Pollard, Andrew J., Quan, T. Phuong, Revale, Santiago, Silva-Reyes, Laura, Richard, Jean-Baptiste, Rich-Griffin, Charlotte, Salio, Mariolina, Sansom, Stephen Nicholas, Sauka-Spengler, Tatjana, Schwessinger, Ron, Sobrinodiaz, Alberto, Stockdale, Lisa, Strickland, Marie, Sun, Bo, Taylor, Chelsea, Taylor, Stephen, Taylor, Adan, Tomic, Adriana, Tong, Orion, Trebes, Amy, Uhlig, Holm, van Grinsven, Erinke, Vendrell, Iolanda, Verheul, Marije, Wang, Guanlin, Wang, Lihui, Wang, Dapeng, Watkinson, Peter, Watson, Robert, Witty, Lorna, Wray, Katherine, Xue, Luzheng, Young, Rebecca K., Zhang, Ping

“…Treatment of severe COVID-19 is currently limited by clinical heterogeneity and incomplete description of specific immune biomarkers. We present here a…”
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Confronting and mitigating the risk of COVID-19 associated pulmonary aspergillosis by Armstrong-James, Darius, Youngs, Jonathan, Bicanic, Tihana, Abdolrasouli, Alireza, Denning, David W, Johnson, Elizabeth, Mehra, Varun, Pagliuca, Tony, Patel, Brijesh, Rhodes, Johanna, Schelenz, Silke, Shah, Anand, van de Veerdonk, Frank L, Verweij, Paul E, White, P Lewis, Fisher, Matthew C

“…The coronavirus disease 2019 (COVID-19) virus caused a wide spectrum of disease in healthy individuals, as well as those with common comorbidities [1]. Severe…”
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HIV and the right not to know: a reply to replies by Youngs, Jonathan, Simmonds, Joshua

“…[...]this reformulating of all harms as being fundamentally about respect for patient autonomy is an example of the very autonomy-monotheism of which we are…”
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Effectiveness of an antifungal stewardship programme at a London teaching hospital 2010–16 by Whitney, Laura, Al-Ghusein, Hasan, Glass, Stephen, Koh, Mickey, Klammer, Matthias, Ball, Jonathan, Youngs, Jonathan, Wake, Rachel, Houston, Angela, Bicanic, Tihana

“…Abstract Background The need for antifungal stewardship is gaining recognition with increasing incidence of invasive fungal infection (IFI) and antifungal…”
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Late presentation of amoebic liver abscess by Dhariwal, Ankush, Youngs, Jonathan, San Francisco, Alberto, Bicanic, Tihana

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COVID-19-associated pulmonary aspergillosis in mechanically ventilated patients: a prospective, multicentre UK study by Hurt, William, Youngs, Jonathan, Ball, Jonathan, Edgeworth, Jonathan, Hopkins, Philip, Jenkins, David R, Leaver, Susannah, Mazzella, Andrea, Molloy, Síle F, Schelenz, Silke, Wise, Matt P, White, P Lewis, Yusuff, Hakeem, Wyncoll, Duncan, Bicanic, Tihana

“…Invasive pulmonary aspergillosis is a complication of severe COVID-19, with regional variation in reported incidence and mortality. We describe the incidence,…”
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Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients by Youngs, Jonathan, Provine, Nicholas M, Lim, Nicholas, Sharpe, Hannah R, Amini, Ali, Chen, Yi-Ling, Luo, Jian, Edmans, Matthew D, Zacharopoulou, Panagiota, Chen, Wentao, Sampson, Oliver, Paton, Robert, Hurt, William J, Duncan, David A, McNaughton, Anna L, Miao, Vincent N, Leaver, Susannah, Wyncoll, Duncan L A, Ball, Jonathan, Hopkins, Philip, Skelly, Donal T, Barnes, Eleanor, Dunachie, Susanna, Ogg, Graham, Lambe, Teresa, Pavord, Ian, Shalek, Alex K, Thompson, Craig P, Xue, Luzheng, Macallan, Derek C, Goulder, Philip, Klenerman, Paul, Bicanic, Tihana

“…Prior studies have demonstrated that immunologic dysfunction underpins severe illness in COVID-19 patients, but have lacked an in-depth analysis of the…”
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Reply to: Concerns regarding the validity of the conclusion in a recently published paper on Roche Liat implementation by Youngs, J., Planche, T., Carrington, D.

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Adjunctive viral cell culture supports treatment decision‐making in patients with secondary humoral immunodeficiency and persistent SARS‐CoV‐2 infection by Pallett, Scott J. C., Wake, Rachel, Youngs, Jonathan, Pope, Cassie, Tan, Ngee Keong, Taylor, Joshua, Hawkins, Lois, Witney, Adam A., Laing, Kenneth G., Monahan, Irene M., Akay, Melek, Cox, Alison, Groppelli, Elisabetta, Kelleher, Peter, Miller, Paul, Bicanic, Tihana

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Fatal COVID-19 outcomes are associated with an antibody response targeting epitopes shared with endemic coronaviruses by McNaughton, Anna L, Paton, Robert S, Edmans, Matthew, Youngs, Jonathan, Wellens, Judith, Phalora, Prabhjeet, Fyfe, Alex, Belij-Rammerstorfer, Sandra, Bolton, Jai S, Ball, Jonathan, Carnell, George W, Dejnirattisai, Wanwisa, Dold, Christina, Eyre, David W, Hopkins, Philip, Howarth, Alison, Kooblall, Kreepa, Klim, Hannah, Leaver, Susannah, Lee, Lian Ni, López-Camacho, César, Lumley, Sheila F, Macallan, Derek C, Mentzer, Alexander J, Provine, Nicholas M, Ratcliff, Jeremy, Slon-Compos, Jose, Skelly, Donal, Stolle, Lucas, Supasa, Piyada, Temperton, Nigel, Walker, Chris, Wang, Beibei, Wyncoll, Duncan, Simmonds, Peter, Lambe, Teresa, Baillie, John Kenneth, Semple, Malcolm G, Openshaw, Peter Jm, Obolski, Uri, Turner, Marc, Carroll, Miles, Mongkolsapaya, Juthathip, Screaton, Gavin, Kennedy, Stephen H, Jarvis, Lisa, Barnes, Eleanor, Dunachie, Susanna, Lourenço, José, Matthews, Philippa C, Bicanic, Tihana, Klenerman, Paul, Gupta, Sunetra, Thompson, Craig P

“…The role of immune responses to previously seen endemic coronavirus epitopes in severe acute respiratory coronavirus 2 (SARS-CoV-2) infection and disease…”
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What has replaced foundation programme work-based assessments? by Youngs, Jonathan, Michael Roberts, C, Patterson, John

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