Search Results - "Young Lim, Won"

Enhanced fungal specificity and in vivo therapeutic efficacy of a C-22-modified FK520 analog against C. neoformans by Rivera, Angela, Young Lim, Won, Park, Eunchong, Dome, Patrick A, Hoy, Michael J, Spasojevic, Ivan, Sun, Sheng, Averette, Anna Floyd, Pina-Oviedo, Sergio, Juvvadi, Praveen R, Steinbach, William J, Ciofani, Maria, Hong, Jiyong, Heitman, Joseph

“…Fungal infections cause significant morbidity and mortality globally. The therapeutic armamentarium against these infections is limited, and the development of…”
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Structure-Guided Synthesis of FK506 and FK520 Analogs with Increased Selectivity Exhibit In Vivo Therapeutic Efficacy against Cryptococcus by Hoy, Michael J, Park, Eunchong, Lee, Hyunji, Lim, Won Young, Cole, D Christopher, DeBouver, Nicholas D, Bobay, Benjamin G, Pierce, Phillip G, Fox, 3rd, David, Ciofani, Maria, Juvvadi, Praveen R, Steinbach, William, Hong, Jiyong, Heitman, Joseph

“…Calcineurin is an essential virulence factor that is conserved across human fungal pathogens, including Cryptococcus neoformans, Aspergillus fumigatus, and…”
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Synthesis and evaluation of cyclopentane-based muraymycin analogs targeting MraY by Kwak, Seung-Hwa, Lim, Won Young, Hao, Aili, Mashalidis, Ellene H., Kwon, Do-Yeon, Jeong, Pyeonghwa, Kim, Mi Jung, Lee, Seok-Yong, Hong, Jiyong

“…Antibiotic resistance is one of the most challenging global health issues and presents an urgent need for the development of new antibiotics. In this regard,…”
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Development of Small Molecule Therapeutics Against Anti-Infectious and Anti-Cancer Drug Resistance Via Structure-Based Drug Design by Lim, Won Young

“…Drug discovery typically involves structure-based drug design based on three-dimensional protein structures and hit/lead compound identification and…”
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Synthesis and evaluation of sulfonyl piperazine LpxH inhibitors by Kwak, Seung-Hwa, Cochrane, C. Skyler, Ennis, Amanda F., Lim, Won Young, Webster, Caroline G., Cho, Jae, Fenton, Benjamin A., Zhou, Pei, Hong, Jiyong

“…[Display omitted] •Synthesis and biochemical evaluation of sulfonyl piperazine LpxH inhibitors.•SAR analysis of sulfonyl piperazine LpxH inhibitors.•Report of…”
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Predictors of poor outcomes in patients with wild mushroom-induced acute liver injury by Kim, Taerim, Lee, Danbi, Lee, Jae Ho, Lee, Yoon-Seon, Oh, Bum Jin, Lim, Kyoung Soo, Kim, Won Young

“…AIM To identify early predictive markers of poor outcomes in patients with acute liver injury from wild mushroom intoxication.METHODS This observational,…”
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Synthesis and evaluation of sulfonyl piperazine LpxH inhibitors by Kwak, Seung-Hwa, Cochrane, C. Skyler, Ennis, Amanda F., Lim, Won Young, Webster, Caroline G., Cho, Jae, Fenton, Benjamin A., Zhou, Pei, Hong, Jiyong

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Ethnic Differences in the Metabolism of Toluene by Ki-Woong Kim, Young Lim Won, Kyung Sun Ko

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Efficient algorithms for multi-dimensional block-cyclic redistribution of arrays by Young Won Lim, Neungsoo Park, Prasanna, V.K.

“…We present a uniform framework for a classical problem, redistribution of a multi-dimensional array. Using a generalized circulant matrix formalism, we derive…”
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Ethnic Differences in the Metabolism of Toluene: Comparisons between Korean and Foreign Workers Exposed to Toluene by Kim, Ki-Woong, Won, Young Lim, Ko, Kyung Sun

“…The objectives of this study were to investigate the individual characteristics, lifestyle habits, exposure levels, and genetic diversity of…”
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A uniform framework for efficient data remapping by Lim, Young Won

“…Data remapping is essential to achieve high performance on distributed memory machines. Data remapping can reduce remote memory access overhead by improving…”
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Gastric leptomeningeal carcinomatosis： Multi-center retrospective analysis of 54 cases by Oh, Sung Yong, Lee, Su-Jin, Lee, Jeeyun, Lee, Suee, Kim, Sung-Hyun, Kwon, Hyuk-Chan, Lee, Gyeong-Won, Kang, Jung-Hun, Hwang, In-Gyu, Jang, Joung-Soon, Lim, Ho-Yeong, Park, Young-Suk, Kang, Won-Ki, Kim, Hyo-Jin

“…AIM： To identify the clinical features and outcomes of infrequently reported leptomeningeal carcinomatosis （LMC） of gastric cancer.METHODS： We analyzed 54…”
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Retrospective analysis of extra-gastrointestinal stromal tumors by Yi, Jun Ho, Park, Byeong-Bae, Kang, Jung Hun, Hwang, In Gyu, Shin, Dong Bok, Sym, Sun Jin, Ahn, Hee Kyung, Lee, Soon Il, Lim, Do Hyoung, Park, Keon Woo, Won, Young-Woong, Lim, Sung Hee, Park, Se Hoon

“…AIM:To investigate the clinicopathologic features of patients with extra-gastrointestinal stromal tumors(EGISTs)in South Korea.METHODS:A total of 51 patients…”
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A uniform framework for efficient data remapping by Lim, Young Won

“…Data remapping is essential to achieve high performance on distributed memory machines. Data remapping can reduce remote memory access overhead by improving…”
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Efficient 8-cycle DES implementation by Young Won Lim

“…This paper describes an efficient DES implementation that encrypts a 64-bit plain text block in 8 clock cycles. The 8 cycle processing latency optimizes the…”
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Parallelization of perceptual grouping on distributed memory machines by Cho-Li Wang, Prasanna, V.K., Young Won Lim

“…We propose architecture independent parallel algorithms for solving perceptual grouping tasks on distributed memory machines. Given an n/spl times/n image,…”
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Efficient algorithms for block-cyclic redistribution of arrays by Young Won Lim, Bhat, P.B., Prasanna, V.K.

“…We present new algorithmic techniques for a classical research problem, runtime redistribution of an array from one block-cyclic layout to another. Our…”
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