Search Results - "Young, T F"

LSD1 is required for euchromatic origin firing and replication timing by Wang, Yue, Huang, Yunchao, Cheng, Edith, Liu, Xinhua, Zhang, Yu, Yang, Jianguo, Young, Jordan T. F., Brown, Grant W., Yang, Xiaohan, Shang, Yongfeng

“…The chromatin-based rule governing the selection and activation of replication origins remains to be elucidated. It is believed that DNA replication initiates…”
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A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice by Escribano-Díaz, Cristina, Orthwein, Alexandre, Fradet-Turcotte, Amélie, Xing, Mengtan, Young, Jordan T.F., Tkáč, Ján, Cook, Michael A., Rosebrock, Adam P., Munro, Meagan, Canny, Marella D., Xu, Dongyi, Durocher, Daniel

“…DNA double-strand break (DSB) repair pathway choice is governed by the opposing activities of 53BP1 and BRCA1. 53BP1 stimulates nonhomologous end joining…”
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The CIP2A-TOPBP1 axis safeguards chromosome stability and is a synthetic lethal target for BRCA-mutated cancer by Adam, Salomé, Rossi, Silvia Emma, Moatti, Nathalie, De Marco Zompit, Mara, Xue, Yibo, Ng, Timothy F, Álvarez-Quilón, Alejandro, Desjardins, Jessica, Bhaskaran, Vivek, Martino, Giovanni, Setiaputra, Dheva, Noordermeer, Sylvie M, Ohsumi, Toshiro K, Hustedt, Nicole, Szilard, Rachel K, Chaudhary, Natasha, Munro, Meagan, Veloso, Artur, Melo, Henrique, Yin, Shou Yun, Papp, Robert, Young, Jordan T F, Zinda, Michael, Stucki, Manuel, Durocher, Daniel

“…BRCA1/2-mutated cancer cells adapt to the genome instability caused by their deficiency in homologous recombination (HR). Identification of these adaptive…”
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Identification and characterization of a Mycoplasma hyopneumoniae adhesin by Zhang, Q. (Iowa State University, Ames, IA.), Young, T.F, Ross, R.F

“…An adhesin of Mycoplasma hyopneumoniae was identified and characterized in this study. A monoclonal antibody (MAb), F2G5, and its F(ab')2 fragments inhibited…”
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The MMS22L-TONSL Complex Mediates Recovery from Replication Stress and Homologous Recombination by O'Donnell, Lara, Panier, Stephanie, Wildenhain, Jan, Tkach, Johnny M., Al-Hakim, Abdallah, Landry, Marie-Claude, Escribano-Diaz, Cristina, Szilard, Rachel K., Young, Jordan T.F., Munro, Meagan, Canny, Marella D., Kolas, Nadine K., Zhang, Wei, Harding, Shane M., Ylanko, Jarkko, Mendez, Megan, Mullin, Michael, Sun, Thomas, Habermann, Bianca, Datti, Alessandro, Bristow, Robert G., Gingras, Anne-Claude, Tyers, Michael D., Brown, Grant W., Durocher, Daniel

“…Genome integrity is jeopardized each time DNA replication forks stall or collapse. Here we report the identification of a complex composed of MMS22L (C6ORF167)…”
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Effect of vaccination on the potentiation of porcine reproductive and respiratory syndrome virus (PRRSV)-induced pneumonia by Mycoplasma hyopneumoniae by Thacker, Eileen L., Thacker, Brad J., Young, Theresa F., Halbur, Patrick G.

“…Porcine reproductive and respiratory syndrome virus (PRRSV) and Mycoplasma hyopneumoniae are frequently isolated pathogens from pigs with respiratory disease…”
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Combined magnetron sputtering and ECR-CVD deposition of diamond-like carbon films by Chang, J.F, Ueng, H.Y, Young, T.F, Wang, Y.C, Hwang, W.C

“…A novel hybrid technique for diamond-like carbon (DLC) film deposition has been developed, which combines the electron cyclotron resonance microwave plasma…”
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CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition by Gallo, David, Young, Jordan T. F., Fourtounis, Jimmy, Martino, Giovanni, Álvarez-Quilón, Alejandro, Bernier, Cynthia, Duffy, Nicole M., Papp, Robert, Roulston, Anne, Stocco, Rino, Szychowski, Janek, Veloso, Artur, Alam, Hunain, Baruah, Prasamit S., Fortin, Alexanne Bonneau, Bowlan, Julian, Chaudhary, Natasha, Desjardins, Jessica, Dietrich, Evelyne, Fournier, Sara, Fugère-Desjardins, Chloe, Goullet de Rugy, Theo, Leclaire, Marie-Eve, Liu, Bingcan, Bhaskaran, Vivek, Mamane, Yael, Melo, Henrique, Nicolas, Olivier, Singhania, Akul, Szilard, Rachel K., Tkáč, Ján, Yin, Shou Yun, Morris, Stephen J., Zinda, Michael, Marshall, C. Gary, Durocher, Daniel

“…Amplification of the CCNE1 locus on chromosome 19q12 is prevalent in multiple tumour types, particularly in high-grade serous ovarian cancer, uterine tumours…”
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Study on annealing effects of Au thin films on Si by Young, T.F, Chang, J.F, Ueng, H.Y

“…We report on the annealing effects of gold thin films deposited on silicon by analyzing the FTIR, AFM and d.c. conductivity, before and after annealing. FTIR…”
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A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities by Vizeacoumar, Franco J, Arnold, Roland, Vizeacoumar, Frederick S, Chandrashekhar, Megha, Buzina, Alla, Young, Jordan T F, Kwan, Julian H M, Sayad, Azin, Mero, Patricia, Lawo, Steffen, Tanaka, Hiromasa, Brown, Kevin R, Baryshnikova, Anastasia, Mak, Anthony B, Fedyshyn, Yaroslav, Wang, Yadong, Brito, Glauber C, Kasimer, Dahlia, Makhnevych, Taras, Ketela, Troy, Datti, Alessandro, Babu, Mohan, Emili, Andrew, Pelletier, Laurence, Wrana, Jeff, Wainberg, Zev, Kim, Philip M, Rottapel, Robert, O'Brien, Catherine A, Andrews, Brenda, Boone, Charles, Moffat, Jason

“…Improved efforts are necessary to define the functional product of cancer mutations currently being revealed through large‐scale sequencing efforts. Using…”
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Microtiter plate adherence assay and receptor analogs for Mycoplasma hyopneumoniae by Zhang, Q, Young, T.F, Ross, R.F

“…A microliter plate adherence assay for Mycoplasma hyopneumoniae was established by use of purified swine tracheal cilia which contained receptors for the…”
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RP-3500: A Novel, Potent, and Selective ATR Inhibitor that is Effective in Preclinical Models as a Monotherapy and in Combination with PARP Inhibitors by Roulston, Anne, Zimmermann, Michal, Papp, Robert, Skeldon, Alexander, Pellerin, Charles, Dumas-Bérube, Émilie, Dumais, Valerie, Dorich, Stéphane, Fader, Lee D, Fournier, Sara, Li, Li, Leclaire, Marie-Eve, Yin, Shou Yun, Chefson, Amandine, Alam, Hunain, Yang, William, Fugère-Desjardins, Chloe, Vignini-Hammond, Sabrina, Skorey, Kathryn, Mulani, Amina, Rimkunas, Victoria, Veloso, Artur, Hamel, Martine, Stocco, Rino, Mamane, Yael, Li, Zuomei, Young, Jordan T F, Zinda, Michael, Black, W Cameron

“…Ataxia telangiectasia and Rad3-related (ATR) kinase protects genome integrity during DNA replication. RP-3500 is a novel, orally bioavailable clinical-stage…”
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Glycolipid receptors for attachment of Mycoplasma hyopneumoniae to porcine respiratory ciliated cells by Zhang, Q. (Iowa State University, Ames, IA.), Young, T.F, Ross, R.F

“…Glycolipid receptors for Mycoplasma hyopneumoniae attachment were analyzed by using a thin-laver chromatography (TLC) overlay assay. M. hyopneumoniae bound…”
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HELB Is a Feedback Inhibitor of DNA End Resection by Tkáč, Ján, Xu, Guotai, Adhikary, Hemanta, Young, Jordan T.F., Gallo, David, Escribano-Díaz, Cristina, Krietsch, Jana, Orthwein, Alexandre, Munro, Meagan, Sol, Wendy, Al-Hakim, Abdallah, Lin, Zhen-Yuan, Jonkers, Jos, Borst, Piet, Brown, Grant W., Gingras, Anne-Claude, Rottenberg, Sven, Masson, Jean-Yves, Durocher, Daniel

“…DNA double-strand break repair by homologous recombination is initiated by the formation of 3′ single-stranded DNA (ssDNA) overhangs by a process termed end…”
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A tissue culture system to study respiratory ciliary epithelial adherence of selected swine mycoplasmas by Young, Theresa F., Thacker, Eileen L., Erickson, Barbara Z., Ross, Richard F.

“…An in vitro culture system for swine tracheal epithelial cells was developed to study the adherence of swine mycoplasmas. Swine tracheal epithelial cells were…”
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Evaluation of the ELISA and comparison to the complement fixation test and radial immunodiffusion enzyme assay for detection of antibodies against Mycoplasma hyopneumoniae in swine serum by Bereiter, M, Young, T F, Joo, H S, Ross, R F

“…An enzyme-linked immunosorbent assay (ELISA) was evaluated for detection of antibodies (Ab) against Mycoplasma hyopneumoniae and M. flocculare in sera from…”
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Endogenous DNA 3′ Blocks Are Vulnerabilities for BRCA1 and BRCA2 Deficiency and Are Reversed by the APE2 Nuclease by Álvarez-Quilón, Alejandro, Wojtaszek, Jessica L., Mathieu, Marie-Claude, Patel, Tejas, Appel, C. Denise, Hustedt, Nicole, Rossi, Silvia Emma, Wallace, Bret D., Setiaputra, Dheva, Adam, Salomé, Ohashi, Yota, Melo, Henrique, Cho, Tiffany, Gervais, Christian, Muñoz, Ivan M., Grazzini, Eric, Young, Jordan T.F., Rouse, John, Zinda, Michael, Williams, R. Scott, Durocher, Daniel

“…The APEX2 gene encodes APE2, a nuclease related to APE1, the apurinic/apyrimidinic endonuclease acting in base excision repair. Loss of APE2 is lethal in cells…”
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Silicide formation of Au thin films on (1 0 0) Si during annealing by Chang, J.F, Young, T.F, Yang, Y.L, Ueng, H.Y, Chang, T.C

“…The formation of gold silicide in gold thin films deposited on Si has been studied by in situ X-ray diffraction (XRD) analysis during annealing up to 500 °C…”
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Study on the Si-Si Vibrational States of the Near Surface Region of Porous Silicon by Young, Tf, Chen, Cp, Liou, Jf, Yang, Yl, Chang, Tc

“…The Si-Si vibrational states near the surface region of porous silicon has been characterized using Fourier Transform Infrared Spectroscopy (FTIR) due to its…”
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Thermal analysis on the degradation of poly-silicon TFTs under AC stress by Weng, C.F., Chang, T.C., Tai, Y.H., Huang, S.T., Wu, K.T., Chen, C.W., Kuo, W.C., Young, T.F.

“…In this work, the degradation mechanism of N-channel poly-silicon thin-film transistor (poly-Si TFT) has been investigated under dynamic voltage stress at room…”
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