Search Results - "Young, SN"

Effects of L‐histidine depletion and L‐tyrosine/L‐phenylalanine depletion on sensory and motor processes in healthy volunteers by Van Ruitenbeek, P, Sambeth, A, Vermeeren, A, Young, SN, Riedel, WJ

“…Background and purpose:  Animal studies show that histamine plays a role in cognitive functioning and that histamine H3‐receptor antagonists, which increase…”
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Ecological momentary assessment: what it is and why it is a method of the future in clinical psychopharmacology by Moskowitz, Debbie S, Young, Simon N

“…Current methods of assessment in clinical psychopharmacology have several serious disadvantages, particularly for the study of social functioning. We aimed to…”
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Acute tryptophan depletion blocks morphine analgesia in the cold-pressor test in humans by ABBOTT, F. V, ETIENNE, P, FRANKLIN, K. B. J, MORGAN, M. J, SEWITCH, M. J, YOUNG, S. N

“…The effects of depletion of the serotonin precursor, L-tryptophan, on the threshold and tolerance to cold pressor pain, and the analgesic effect of morphine…”
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The role of serotonin in human mood and social interaction: Insight from altered tryptophan levels by Young, Simon N., Leyton, Marco

“…Alterations in brain tryptophan levels cause changes in brain serotonin synthesis, and this has been used to study the implication of altered serotonin levels…”
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Differences between Males and Females in Rates of Serotonin Synthesis in Human Brain by Nishizawa, S., Benkelfat, C., Young, S. N., Leyton, M., Mzengeza, S., De Montigny, C., Blier, P., Diksic, M.

“…Rates of serotonin synthesis were measured in the human brain using positron emission tomography. The sensitivity of the method is indicated by the fact that…”
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Study of the brain serotonergic system with labeled α‐methyl‐l‐tryptophan by Diksic, Mirko, Young, Simon N.

“…α‐Methyl‐l‐tryptophan (α‐MTrp) is an artificial amino acid and an analog of tryptophan (Trp), the precursor of the neurotransmitter serotonin (5‐HT). In this…”
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Decreasing Amphetamine-Induced Dopamine Release by Acute Phenylalanine Tyrosine Depletion: A PET [ C]Raclopride Study in Healthy Men by LEYTON, Marco, DAGHER, Alain, BOILEAU, Isabelle, CASEY, Kevin, BAKER, Glen B, DIKSIC, Mirko, GUNN, Roger, YOUNG, Simon N, BENKELFAT, Chawki

“…Acute phenylalanine/tyrosine depletion (APTD) has been proposed as a new method to decrease catecholamine neurotransmission safely, rapidly, and transiently…”
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The Effect of Tryptophan on Social Interaction in Everyday Life: A Placebo-Controlled Study by Moskowitz, D.S, Pinard, Gilbert, Zuroff, David C, Annable, Lawrence, Young, Simon N

“…In monkeys increasing serotonin function enhances affiliative interactions and promotes the acquisition of dominance. To examine whether similar effects occur…”
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The effect of methionine and S-adenosylmethionine on S-adenosylmethionine levels in the rat brain by YOUNG, Simon N, SHALCHI, Marjan

“…S-Adenosylmethionine (SAMe) is a major methyl donor in the brain and is also an antidepressant with few reported side effects; however, SAMe is relatively…”
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Prolonged and unsoothable crying bouts in infants with and without colic by BARR, Ronald G, PATERSON, Jodi A, MACMARTIN, Lisa M, LEHTONEN, Liisa, YOUNG, Simon N

“…The authors sought to determine which features of early distress were "excessive" and specific to the first months of life as described by diary recordings. In…”
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Sweet taste and blood pressure-related analgesia by Lewkowski, Maxim D, Ditto, Blaine, Roussos, Marios, Young, Simon N

“…To test the prediction that sweet taste modifies responses to cold induced pain, 72 young adults held sweet, bitter and water solutions in their mouths, in…”
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Lack of Effects on Core Obsessive-Compulsive Symptoms of Tryptophan Depletion During Symptom Provocation in Remitted Obsessive-Compulsive Disorder Patients by Berney, Alexandre, Sookman, Debbie, Leyton, Marco, Young, Simon N., Benkelfat, Chawki

“…Pharmacological evidence support that enhancement of serotonin (5-HT) neurotransmission is critical for treatment efficacy in obsessive-compulsive disorder…”
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Clinical nutrition: 3. The fuzzy boundary between nutrition and psychopharmacology by Young, Simon N

“…There are many popular beliefs about the effects of diet on mood and behaviour. No one doubts that food ingestion can influence mood and behaviour, but the…”
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Serotonin function, personality-trait variations, and childhood abuse in women with bulimia-spectrum eating disorders by STEIGER, Howard, GAUVIN, Lise, ISRAËL, Mimi, NG YING KIN, N. M. K, YOUNG, Simon N, ROUSSIN, Julie

“…Across populations, findings associate impulsivity, behavioral disinhibition, or hostility with reduced central serotonin (5-hydroxytryptamine: 5-HT) activity…”
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Behavioral Disinhibition Induced by Tryptophan Depletion in Nonalcoholic Young Men With Multigenerational Family Histories of Paternal Alcoholism by LeMarquand, David G., Benkelfat, Chawki, Pihl, Robert O., Palmour, Roberta M., Young, Simon N.

“…OBJECTIVE: A deficit in serotonergic neurotransmission has been linked to impulsive behavior, as well as to disorders characterized by disinhibition. The…”
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Mood response to acute tryptophan depletion in healthy volunteers: Sex differences and temporal stability by Ellenbogen, Mark A., Young, Simon N., Dean, Peggy, Palmour, Roberta M., Benkelfat, Chawki

“…We investigated (1) the mood response of normal women, without a family history of major affective disorder, to acute tryptophan depletion, and (2) the…”
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A rant against jargon and neologisms by Young, Simon N

“…Life scientists and, in particular, neuroscientists are just as bad with prefixes as with suffixes. Neuro- can be put in front of anything so, for example, we…”
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Cortical trapping of [alpha]-[11C]methyl-l-tryptophan, an index of serotonin synthesis, is lower in females than males by Sakai, Y, Nishikawa, M, Leyton, M, Benkelfat, C, Young, SN, Diksic, M

“…One neural system that may exhibit gender differences is serotonin (5-HT), a neurotransmitter implicated in the regulation of mood, cognitive processes, and…”
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Effects on Mood of Acute Phenylalanine/Tyrosine Depletion in Healthy Women by Leyton, M., Young, S.N., Pihl, R.O., Etezadi, S., Lauze, C., Blier, P., Baker, G.B., Benkelfat, C.

“…Catecholamines have been implicated in the etiology and pathophysiology of mood and anxiety disorders. In the present study, we investigated the effects of…”
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Association of the promoter polymorphism −1438G/A of the 5-HT2A receptor gene with behavioral impulsiveness and serotonin function in women with bulimia nervosa by Bruce, Kenneth R., Steiger, Howard, Joober, Ridha, Kin, N.M.K. Ng Ying, Israel, Mimi, Young, Simon N.

“…Separate lines of research suggest that the functional alterations in the serotonin (5‐HT) 2A receptor are associated with 5‐HT tone, behavioral impulsiveness,…”
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