Search Results - "Young, Rodrigo M"

Refine Results
  1. 1
  2. 2
  3. 3
  4. 4

    Developmentally regulated Tcf7l2 splice variants mediate transcriptional repressor functions during eye formation by Young, Rodrigo M, Ewan, Kenneth B, Ferrer, Veronica P, Allende, Miguel L, Godovac-Zimmermann, Jasminka, Dale, Trevor C, Wilson, Stephen W

    Published in eLife (12-12-2019)
    “…Tcf7l2 mediates Wnt/β-Catenin signalling during development and is implicated in cancer and type-2 diabetes. The mechanisms by which Tcf7l2 and Wnt/β-Catenin…”
    Get full text
    Journal Article
  5. 5
  6. 6
  7. 7
  8. 8
  9. 9

    Transcriptome profiling of zebrafish optic fissure fusion by Richardson, R., Owen, N., Toms, M., Young, Rodrigo M., Tracey-White, D., Moosajee, M.

    Published in Scientific reports (07-02-2019)
    “…Incomplete fusion of the optic fissure leads to ocular coloboma, a congenital eye defect that affects up to 7.5 per 10,000 births and accounts for up to 10…”
    Get full text
    Journal Article
  10. 10
  11. 11

    Expanding the phenotypic spectrum consequent upon de novo WDR37 missense variants by Hay, Eleanor, Henderson, Robert H., Mansour, Sahar, Deshpande, Charu, Jones, Rachel, Nutan, Savita, Mankad, Kshitij, Young, Rodrigo M., Moosajee, Mariya, Research Consortium, Genomics England, Arno, Gavin

    Published in Clinical genetics (01-08-2020)
    “…Structural eye disorders are increasingly recognised as having a genetic basis, although current genetic testing is limited in its success. De novo missense…”
    Get full text
    Journal Article
  12. 12
  13. 13
  14. 14
  15. 15

    HESX1- and TCF3-mediated repression of Wnt/β-catenin targets is required for normal development of the anterior forebrain by Andoniadou, Cynthia L, Signore, Massimo, Young, Rodrigo M, Gaston-Massuet, Carles, Wilson, Stephen W, Fuchs, Elaine, Martinez-Barbera, Juan Pedro

    Published in Development (Cambridge) (15-11-2011)
    “…The Wnt/β-catenin pathway plays an essential role during regionalisation of the vertebrate neural plate and its inhibition in the most anterior neural ectoderm…”
    Get full text
    Journal Article
  16. 16
  17. 17

    Early Stages of Zebrafish Eye Formation Require the Coordinated Activity of Wnt11, Fz5, and the Wnt/β-Catenin Pathway by Cavodeassi, Florencia, Carreira-Barbosa, Filipa, Young, Rodrigo M., Concha, Miguel L., Allende, Miguel L., Houart, Corinne, Tada, Masazumi, Wilson, Stephen W.

    Published in Neuron (Cambridge, Mass.) (07-07-2005)
    “…During regional patterning of the anterior neural plate, a medially positioned domain of cells is specified to adopt retinal identity. These eye field cells…”
    Get full text
    Journal Article
  18. 18
  19. 19

    Expression and splice variant analysis of the zebrafish tcf4 transcription factor by Young, Rodrigo M., Reyes, Ariel E., Allende, Miguel L.

    Published in Mechanisms of development (01-09-2002)
    “…Wnt signalling has been implicated in antero-posterior patterning of the vertebrate embryonic body axis and in a number of other developmental processes. One…”
    Get full text
    Journal Article
  20. 20

    Zebrafish yolk‐specific not really started (nrs) gene is a vertebrate homolog of the Drosophila spinster gene and is essential for embryogenesis by Young, Rodrigo M., Marty, Scott, Nakano, Yoshiro, Wang, Han, Yamamoto, Daisuke, Lin, Shuo, Allende, Miguel L.

    Published in Developmental dynamics (01-03-2002)
    “…By using retroviral insertional mutagenesis in zebrafish, we have identified a recessive lethal mutation in the not really started (nrs) gene. The nrs mutation…”
    Get full text
    Journal Article