Search Results - "Young, Robert J."

Mechanical properties of graphene and graphene-based nanocomposites by Papageorgiou, Dimitrios G., Kinloch, Ian A., Young, Robert J.

“…In this present review, the current status of the intrinsic mechanical properties of the graphene-family of materials along with the preparation and properties…”
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Expanding the medicinal chemistry synthetic toolbox by Boström, Jonas, Brown, Dean G., Young, Robert J., Keserü, György M.

“…Analysis of the role of synthetic organic chemistry in the identification of chemical starting points for drug discovery and subsequent optimization into…”
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Mapping the Efficiency and Physicochemical Trajectories of Successful Optimizations by Young, Robert J, Leeson, Paul D

“…The practices and tactics employed in successful optimizations are examined, judged from the trajectories of ligand efficiency and property evolution. A wide…”
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The mechanics of graphene nanocomposites: A review by Young, Robert J., Kinloch, Ian A., Gong, Lei, Novoselov, Kostya S.

“…The preparation and characterisation of the different forms of graphene are reviewed first of all. The different techniques that have been employed to prepare…”
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Sensitive electromechanical sensors using viscoelastic graphene-polymer nanocomposites by Boland, Conor S., Khan, Umar, Ryan, Gavin, Barwich, Sebastian, Charifou, Romina, Harvey, Andrew, Backes, Claudia, Li, Zheling, Ferreira, Mauro S., Möbius, Matthias E., Young, Robert J., Coleman, Jonathan N.

“…Despite its widespread use in nanocomposites, the effect of embedding graphene in highly viscoelastic polymer matrices is not well understood. We added…”
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Two-Step Electrochemical Intercalation and Oxidation of Graphite for the Mass Production of Graphene Oxide by Cao, Jianyun, He, Pei, Mohammed, Mahdi A, Zhao, Xin, Young, Robert J, Derby, Brian, Kinloch, Ian A, Dryfe, Robert A. W

“…Conventional chemical oxidation routes for the production of graphene oxide (GO), such as the Hummers’ method, suffer from environmental and safety issues due…”
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Impact of image preprocessing on the scanner dependence of multi-parametric MRI radiomic features and covariate shift in multi-institutional glioblastoma datasets by Um, Hyemin, Tixier, Florent, Bermudez, Dalton, Deasy, Joseph O, Young, Robert J, Veeraraghavan, Harini

“…Recent advances in radiomics have enhanced the value of medical imaging in various aspects of clinical practice, but a crucial component that remains to be…”
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Edible unclonable functions by Leem, Jung Woo, Kim, Min Seok, Choi, Seung Ho, Kim, Seong-Ryul, Kim, Seong-Wan, Song, Young Min, Young, Robert J., Kim, Young L.

“…Counterfeit medicines are a fundamental security problem. Counterfeiting medication poses a tremendous threat to patient safety, public health, and the economy…”
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Quantitative imaging biomarkers alliance (QIBA) recommendations for improved precision of DWI and DCE‐MRI derived biomarkers in multicenter oncology trials by Shukla‐Dave, Amita, Obuchowski, Nancy A., Chenevert, Thomas L., Jambawalikar, Sachin, Schwartz, Lawrence H., Malyarenko, Dariya, Huang, Wei, Noworolski, Susan M., Young, Robert J., Shiroishi, Mark S., Kim, Harrison, Coolens, Catherine, Laue, Hendrik, Chung, Caroline, Rosen, Mark, Boss, Michael, Jackson, Edward F.

“…Physiological properties of tumors can be measured both in vivo and noninvasively by diffusion‐weighted imaging and dynamic contrast‐enhanced magnetic…”
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Interfacial Stress Transfer in a Graphene Monolayer Nanocomposite by Gong, Lei, Kinloch, Ian A., Young, Robert J., Riaz, Ibtsam, Jalil, Rashid, Novoselov, Konstantin S.

“…It is demonstrated from stress‐induced Raman bands shiftsthat stress can be transferred from a polymer matrix to a graphene monolayer (see image) in a model…”
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Ivosidenib in Isocitrate Dehydrogenase 1 - Mutated Advanced Glioma by Mellinghoff, Ingo K, Ellingson, Benjamin M, Touat, Mehdi, Maher, Elizabeth, De La Fuente, Macarena I, Holdhoff, Matthias, Cote, Gregory M, Burris, Howard, Janku, Filip, Young, Robert J, Huang, Raymond, Jiang, Liewen, Choe, Sung, Fan, Bin, Yen, Katharine, Lu, Min, Bowden, Chris, Steelman, Lori, Pandya, Shuchi S, Cloughesy, Timothy F, Wen, Patrick Y

“…Diffuse gliomas are malignant brain tumors that include lower-grade gliomas (LGGs) and glioblastomas. Transformation of low-grade glioma into a higher tumor…”
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Background, current role, and potential applications of radiogenomics by Pinker, Katja, Shitano, Fuki, Sala, Evis, Do, Richard K., Young, Robert J., Wibmer, Andreas G., Hricak, Hedvig, Sutton, Elizabeth J., Morris, Elizabeth A.

“…With the genomic revolution in the early 1990s, medical research has been driven to study the basis of human disease on a genomic level and to devise precise…”
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Vorasidenib, a Dual Inhibitor of Mutant IDH1/2, in Recurrent or Progressive Glioma; Results of a First-in-Human Phase I Trial by Mellinghoff, Ingo K, Penas-Prado, Marta, Peters, Katherine B, Burris, 3rd, Howard A, Maher, Elizabeth A, Janku, Filip, Cote, Gregory M, de la Fuente, Macarena I, Clarke, Jennifer L, Ellingson, Benjamin M, Chun, Saewon, Young, Robert J, Liu, Hua, Choe, Sung, Lu, Min, Le, Kha, Hassan, Islam, Steelman, Lori, Pandya, Shuchi S, Cloughesy, Timothy F, Wen, Patrick Y

“…Lower grade gliomas (LGGs) are malignant brain tumors. Current therapy is associated with short- and long-term toxicity. Progression to higher tumor grade is…”
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Optimizing the Reinforcement of Polymer-Based Nanocomposites by Graphene by Gong, Lei, Young, Robert J, Kinloch, Ian A, Riaz, Ibtsam, Jalil, Rashid, Novoselov, Kostya S

“…The stress transfer between the internal layers of multilayer graphene within polymer-based nanocomposites has been investigated from the stress-induced shifts…”
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Control of the functionality of graphene oxide for its application in epoxy nanocomposites by Li, Zheng, Wang, Rongguo, Young, Robert J., Deng, Libo, Yang, Fan, Hao, Lifeng, Jiao, Weicheng, Liu, Wenbo

“…Amino- and epoxy-functionalized graphene oxide (GO) were synthesized separately through a wash-and-rebuild process utilizing two differently terminated silane…”
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The impact of aromatic ring count on compound developability: further insights by examining carbo- and hetero-aromatic and -aliphatic ring types by Ritchie, Timothy J., Macdonald, Simon J.F., Young, Robert J., Pickett, Stephen D.

“…The impact of carboaromatic, heteroaromatic, carboaliphatic and heteroaliphatic ring counts and fused aromatic ring count on several developability measures…”
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Street trees reduce the negative effects of urbanization on birds by Pena, João Carlos de Castro, Martello, Felipe, Ribeiro, Milton Cezar, Armitage, Richard A, Young, Robert J, Rodrigues, Marcos

“…The effects of streets on biodiversity is an important aspect of urban ecology, but it has been neglected worldwide. Several vegetation attributes (e.g. street…”
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Self-assembly of a layered two-dimensional molecularly woven fabric by August, David P., Dryfe, Robert A. W., Haigh, Sarah J., Kent, Paige R. C., Leigh, David A., Lemonnier, Jean-François, Li, Zheling, Muryn, Christopher A., Palmer, Leoni I., Song, Yiwei, Whitehead, George F. S., Young, Robert J.

“…Fabrics—materials consisting of layers of woven fibres—are some of the most important materials in everyday life 1 . Previous nanoscale weaves 2 – 16 include…”
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Marked Response of a Hypermutated ACTH-Secreting Pituitary Carcinoma to Ipilimumab and Nivolumab by Lin, Andrew L, Jonsson, Philip, Tabar, Viviane, Yang, T Jonathan, Cuaron, John, Beal, Katherine, Cohen, Marc, Postow, Michael, Rosenblum, Marc, Shia, Jinru, DeAngelis, Lisa M, Taylor, Barry S, Young, Robert J, Geer, Eliza B

“…Pituitary carcinoma is a rare and aggressive malignancy with a poor prognosis and few effective treatment options. A 35-year-old woman presented with an…”
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Long-term risk of radionecrosis and imaging changes after stereotactic radiosurgery for brain metastases by Kohutek, Zachary A., Yamada, Yoshiya, Chan, Timothy A., Brennan, Cameron W., Tabar, Viviane, Gutin, Philip H., Jonathan Yang, T., Rosenblum, Marc K., Ballangrud, Åse, Young, Robert J., Zhang, Zhigang, Beal, Kathryn

“…Radionecrosis is a well-characterized effect of stereotactic radiosurgery (SRS) and is occasionally associated with serious neurologic sequelae. Here, we…”
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