Search Results - "Young, Lesley L."

MEDI1873, a potent, stabilized hexameric agonist of human GITR with regulatory T-cell targeting potential by Tigue, Natalie J., Bamber, Lisa, Andrews, John, Ireland, Samantha, Hair, James, Carter, Edward, Sridharan, Sudharsan, Jovanović, Jelena, Rees, D. Gareth, Springall, Jeremy S., Solier, Emilie, Li, Yi-Ming, Chodorge, Matthieu, Perez-Martinez, David, Higazi, Daniel R., Oberst, Michael, Kennedy, Maureen, Black, Chelsea M., Yan, Li, Schwickart, Martin, Maguire, Shaun, Cann, Jennifer A., de Haan, Lolke, Young, Lesley L., Vaughan, Tristan, Wilkinson, Robert W., Stewart, Ross

“…Glucocorticoid-induced tumor necrosis factor receptor-related protein (GITR) is part of a system of signals involved in controlling T-cell activation…”
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Notch ligation by Delta1 inhibits peripheral immune responses to transplantation antigens by a CD8+ cell-dependent mechanism by Wong, Kenneth K, Carpenter, Matthew J, Young, Lesley L, Walker, Susan J, McKenzie, Grahame, Rust, Alyson J, Ward, George, Packwood, Laura, Wahl, Karen, Delriviere, Luc, Hoyne, Gerard, Gibbs, Paul, Champion, Brian R, Lamb, Jonathan R, Dallman, Margaret J

“…Notch signaling plays a fundamental role in determining the outcome of differentiation processes in many tissues. Notch signaling has been implicated in T…”
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The Rat cim Effect: TAP Allele-Dependent Changes in a Class I MHC Anchor Motif and Evidence Against C-Terminal Trimming of Peptides in the ER by Powis, Simon J, Young, Lesley L, Joly, Etienne, Barker, Patrick J, Richardson, Louise, Brandt, Remco P, Melief, Cornelis J, Howard, Jonathan C, Butcher, Geoffrey W

“…Functional polymorphism in the rat peptide transporter associated with antigen processing (TAP) changes the peptide pool available for binding and presentation…”
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Notch signalling in the regulation of peripheral T-cell function by Mckenzie, Grahame J., Young, Lesley L., Briend, Emmanuel, Lamb, Jonathan R., Dallman, Margaret J., Champion, Brian R.

“…The Notch signalling pathway plays a highly-conserved role in regulating the cellular differentiation and proliferation events that characterise pattern…”
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Modulation of the notch pathway for immunotherapy by Briend, Emmanuel, Young, Lesley L, McKenzie, Grahame J, Tugal, Tamara, Ragno, Silvia, Champion, Brian R

“…Since its initial description as a neurogenic locus in Drosophila, the Notch pathway has been shown to play a central role in cell fate decisions across…”
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Notch ligation by Delta1 inhibits peripheral immune responses to transplantation antigens by a CD8^sup +^ cell-dependent mechanism by Wong, Kenneth K, Carpenter, Matthew J, Young, Lesley L, Walker, Susan J

“…Notch signaling plays a fundamental role in determining the outcome of differentiation processes in many tissues. Notch signaling has been implicated in T…”
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Identification of the rat maternally transmitted minor histocompatibility antigen by Bhuyan, PK, Young, LL, Lindahl, KF, Butcher, GW

“…The rat maternally transmitted Ag has been previously described as a minor histocompatibility Ag composed of a mitochondrially transmitted factor (MTF) and the…”
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