Search Results - "Young, Juan J"
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Validation of a Simplified Tissue-to-Reference Ratio Measurement Using SUVR to Assess Synaptic Density Alterations in Alzheimer Disease with [ 11 C]UCB-J PET
Published in Journal of Nuclear Medicine (01-11-2024)“…Simplified methods of acquisition and quantification would facilitate the use of synaptic density imaging in multicenter and longitudinal studies of Alzheimer…”
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2016 Highlighted Papers for the Practicing Geriatric Mental Health Clinical Provider
Published in The American journal of geriatric psychiatry (01-03-2017)Get full text
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Evidence for using pimavanserin for the treatment of Parkinson's disease psychosis
Published in World journal of psychiatry (10-06-2019)“…The aim of this editorial is to evaluate the evidence for using pimavanserin for the treatment of Parkinson's disease psychosis (PDP) from randomized…”
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Cannabinoids for the treatment of behavioral and psychological symptoms of dementia
Published in Neurodegenerative disease management (01-08-2018)“…[...]additional pharmacological strategies need to be identified that are more suitable for use among individuals with BPSD. There were two randomized…”
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Sex‐specific DNA methylation differences associated with Alzheimer’s disease
Published in Alzheimer's & dementia (01-06-2023)“…Background Sex has increasingly been recognized as an important factor contributing to the heterogeneity in Alzheimer’s disease (AD). Method We performed a…”
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Investigating a CD8+ T cell age‐associated gene signature in Alzheimer's disease
Published in Alzheimer's & dementia (01-12-2022)“…Background Neuroinflammation has been linked with the pathologic progression of Alzheimer’s disease (AD). Previous studies focused primarily on the innate…”
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Harnessing Chromatin 3D interactions to Understand Ancestry‐Specific Alzheimer Disease (AD) risk
Published in Alzheimer's & dementia (01-12-2022)“…Background Ancestry‐specific Alzheimer Disease (AD) genetic risk is well recognized. Chromatin 3D interaction map in AD‐relevant cells with different…”
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Intragenic loci within TOMM40 enhances APOE expression in human microglia
Published in Alzheimer's & dementia (01-12-2022)“…Background Previously, we demonstrated that the ancestry‐related risk for Late Onset Alzheimer’s Disease (LOAD) is driven by a local genomic region (termed…”
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2017 Highlighted Papers for the Geriatric Mental Health Clinical Provider
Published in The American journal of geriatric psychiatry (01-03-2018)Get full text
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Session 312 - 2017 Highlighted Papers for the Geriatric Mental Health Clinical Provider
Published in The American journal of geriatric psychiatry (01-03-2018)Get full text
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Astrocyte specific chromatin accessibility differences in European vs African Alzheimer Disease brains
Published in Alzheimer's & dementia (01-12-2022)“…Background The APOE4 gene, the strongest genetic risk factor for late‐onset Alzheimer disease (AD), is highly expressed in astrocytes. The local ancestry (LA)…”
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Using Oligodendrocytes for studies in Alzheimer disease
Published in Alzheimer's & dementia (01-12-2022)“…Background Genomic regulatory architecture (GRA) has been primarily studied in European ancestry. As part of the functional Consortium of the Alzheimer Disease…”
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A Novel Protective locus significantly reduces the ApoEε4 risk for Alzheimer’s Disease in individuals of African Ancestry
Published in Alzheimer's & dementia (01-12-2022)“…Background African ancestry populations have a lower risk for developing Alzheimer disease (AD) from ApoEε4 compared to other populations. Understanding this…”
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Session 100 - 2016 Highlighted Papers for the Practicing Geriatric Mental Health Clinical Provider
Published in The American journal of geriatric psychiatry (01-03-2017)Get full text
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Validation of a Simplified Tissue-to-Reference Ratio Measurement Using SUVR to Assess Synaptic Density Alterations in Alzheimer Disease with 11CUCB-J PET
Published in The Journal of nuclear medicine (1978) (01-11-2024)“…Simplified methods of acquisition and quantification would facilitate the use of synaptic density imaging in multicenter and longitudinal studies of Alzheimer…”
Get full text
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Personality and the risk factors for developing behavioral and psychological symptoms of dementia: a narrative review
Published in Neurodegenerative disease management (01-04-2019)“…Premorbid personality traits have been implicated as risk factors for the development of behavioral and psychological symptoms of dementia (BPSD), although…”
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