Search Results - "Young, Jamie"

Diabetic‑induced alterations in hepatic glucose and lipid metabolism: The role of type 1 and type 2 diabetes mellitus (Review) by Jiang, Saizhi, Young, Jamie L, Wang, Kai, Qian, Yan, Cai, Lu

“…Diabetes mellitus (DM) is a growing health concern in society. Type 1 and type 2 DM are the two main types of diabetes; both types are chronic diseases that…”
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Implications for prenatal cadmium exposure and adverse health outcomes in adulthood by Young, Jamie L., Cai, Lu

“…Cadmium is a ubiquitous, non-essential metal that has earned a spot on the World Health Organizations top 10 chemicals of major public health concern. The…”
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Current understanding of hexavalent chromium [Cr(VI)] neurotoxicity and new perspectives by Wise, John P., Young, Jamie L., Cai, Jun, Cai, Lu

“…[Display omitted] •Cr(VI) is a major public health concern for neurotoxicity.•Cr(VI) literature suggests it does not contribute to brain cancers.•Cr(VI)( may…”
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Exposure to low-dose cadmium induces testicular ferroptosis by Xiong, Lijuan, Bin Zhou, Young, Jamie L., Wintergerst, Kupper, Cai, Lu

“…As an environmental pollutant, cadmium (Cd) has been widely reported to induce male infertility due to its gonadotoxicity. However, the specific mechanism of…”
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Does maternal low-dose cadmium exposure increase the risk of offspring to develop metabolic syndrome and/or type 2 diabetes? by Saedi, Saman, Watson, Sara E., Young, Jamie L., Tan, Yi, Wintergerst, Kupper A., Cai, Lu

“…Cadmium is a hazardous metal with multiple organ toxicity that causes great harm to human health. Cadmium enters the human body through occupational exposure,…”
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Effects of whole-life exposure to low-dose cadmium with post-weaning high-fat diet on offspring testes in a male mouse model by Xiong, Lijuan, Zhou, Bin, Young, Jamie L., Xu, Jianxiang, Wintergerst, Kupper, Cai, Lu

“…Although several studies have reported testicular impairments caused by cadmium (Cd) or obesity alone, the combined effect of Cd and obesity on the testes and…”
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Impact of prenatal arsenic exposure on chronic adult diseases by Young, Jamie L., Cai, Lu, States, J. Christopher

“…Exposure to environmental stressors during susceptible windows of development can result in negative health outcomes later in life, a concept known as the…”
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Whole life exposure to low dose cadmium alters diet-induced NAFLD by Young, Jamie L., Cave, Matthew C., Xu, Qian, Kong, Maiying, Xu, Jianxiang, Lin, Qian, Tan, Yi, Cai, Lu

“…Nonalcoholic fatty liver disease (NAFLD) is a major global public health concern affecting more than 25% of the world's population. Although obesity and…”
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Sex differences in the effects of whole-life, low-dose cadmium exposure on postweaning high-fat diet-induced cardiac pathogeneses by Zhou, Wenqian, Young, Jamie L., Men, Hongbo, Zhang, Haina, Yu, Haitao, Lin, Qian, Xu, He, Xu, Jianxiang, Tan, Yi, Zheng, Yang, Cai, Lu

“…We previously showed the development of cardiac remodeling (hypertrophy or fibrosis) in mice with either post-weaning high-fat diet (HFD, 60% kcal fat) feeding…”
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Reduction of misleading (“false”) positive results in mammalian cell genotoxicity assays. I. Choice of cell type by Fowler, Paul, Smith, Katie, Young, Jamie, Jeffrey, Laura, Kirkland, David, Pfuhler, Stefan, Carmichael, Paul

“…Current in vitro mammalian cell genotoxicity assays show a high rate of positive results, many of which are misleading when compared with in vivo genotoxicity…”
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Chronic exposure to arsenic and high fat diet induces sex-dependent pathogenic effects on the kidney by Zhang, Yixian, Young, Jamie L., Cai, Lu, Tong, Yong Guang, Miao, Lining, Freedman, Jonathan H.

“…Both obesity and arsenic exposure are global public health problems that are associated with increased risk of renal disease. The effect of whole-life exposure…”
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Nonclinical safety assessment of repeated administration and biodistribution of a novel rabies self-amplifying mRNA vaccine in rats by Stokes, Alan, Pion, Johanne, Binazon, Ornella, Laffont, Benoit, Bigras, Maude, Dubois, Guillaume, Blouin, Karine, Young, Jamie K., Ringenberg, Michael A., Ben Abdeljelil, Nawel, Haruna, Julius, Rodriguez, Luis-Alexander

“…The novel self-amplifying mRNA (SAM) technology for vaccines consists of an engineered replication-deficient alphavirus genome encoding an RNA-dependent RNA…”
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Direct Observation of Hydrogen Tunneling Dynamics in Photoexcited Phenol by Roberts, Gareth M, Chatterley, Adam S, Young, Jamie D, Stavros, Vasilios G

“…The excited-state dynamics of phenol following ultraviolet (UV) irradiation have received considerable interest in recent years, most notably because they can…”
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The environmental pollutant, polychlorinated biphenyl 126, alters liver function in a rodent model of alcohol‐associated liver disease by Gripshover, Tyler C., Wahlang, Banrida, Head, Kimberly Z., Young, Jamie L., Luo, Jianzhu, Mustafa, Muhammad T., Kirpich, Irina A., Cave, Matthew C.

“…Background The prevalence of alcohol‐associated liver disease (ALD), a subtype of fatty liver disease (FLD), continues to rise. ALD is a major cause of…”
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Editorial: Cardiovascular diseases related to diabetes and obesity, volume III by Xin, Ying, Wise, Jamie Young, Rajesh, Mohanraj, Cai, Lu

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Editorial: Cardiovascular diseases related to diabetes and obesity – volume II by Young, Jamie L., Xin, Ying, Rajesh, Mohanraj, Cai, Lu

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Can Zinc Supplementation Attenuate High Fat Diet-Induced Non-Alcoholic Fatty Liver Disease? by Bolatimi, Oluwanifemi Esther, Head, Kimberly Z, Luo, Jianzhu, Gripshover, Tyler C, Lin, Qian, Adiele, Ngozi V, Watson, Walter H, Wilkerson, Caitlin, Cai, Lu, Cave, Matthew C, Young, Jamie L

“…The pathogenesis of non-alcoholic fatty liver disease (NAFLD), the most prevalent chronic liver disease, is associated with zinc deficiency. Previous studies…”
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Cadmium and High-Fat Diet Disrupt Renal, Cardiac and Hepatic Essential Metals by Young, Jamie L., Yan, Xiaofang, Xu, Jianxiang, Yin, Xinmin, Zhang, Xiang, Arteel, Gavin E., Barnes, Gregory N., States, J. Christopher, Watson, Walter H., Kong, Maiying, Cai, Lu, Freedman, Jonathan H.

“…Exposure to the environmental toxicant cadmium (Cd) contributes to the development of obesity-associated diseases. Obesity is a risk factor for a spectrum of…”
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Long-term association of serum selenium levels and the diabetes risk: Findings from a case-control study nested in the prospective Jinchang Cohort by Cheng, Zhiyuan, Li, Yuanyuan, Young, Jamie L., Cheng, Ning, Yang, Chenhui, Papandonatos, George D., Kelsey, Karl T., Wise, John Pierce, Shi, Kunchong, Zheng, Tongzhang, Liu, Simin, Bai, Yana

“…An increasing body of evidence implicates high levels of selenium intake in the development of diabetes, although prospective studies remain sparse. We…”
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Gender Differences in Cardiac Remodeling Induced by a High-Fat Diet and Lifelong, Low-Dose Cadmium Exposure by Liang, Yaqin, Young, Jamie L, Kong, Maiying, Tong, Yongguang, Qian, Yan, Freedman, Jonathan H, Cai, Lu

“…Childhood obesity, which is prevalent in developed countries, is a metabolic risk factor for cardiovascular disease. Cadmium (Cd), a ubiquitous environmental…”
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