Food Intake REstriction for Health OUtcome Support and Education (FIREHOUSE) Protocol: A Randomized Clinical Trial

Fire Department of New York (FDNY) rescue and recovery workers exposed to World Trade Center (WTC) particulates suffered loss of forced expiratory volume in 1 s (FEV ). Metabolic Syndrome increased the risk of developing WTC-lung injury (WTC-LI) We aim to attenuate the deleterious effects of WTC exp...

Full description

Saved in:

Bibliographic Details
Published in:	International journal of environmental research and public health Vol. 17; no. 18; p. 6569
Main Authors:	Kwon, Sophia, Riggs, Jessica, Crowley, George, Lam, Rachel, Young, Isabel R, Nayar, Christine, Sunseri, Maria, Mikhail, Mena, Ostrofsky, Dean, Veerappan, Arul, Zeig-Owens, Rachel, Schwartz, Theresa, Colbeth, Hilary, Liu, Mengling, Pompeii, Mary Lou, St-Jules, David, Prezant, David J, Sevick, Mary Ann, Nolan, Anna
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 09-09-2020 MDPI
Subjects:	Abdomen Activities of Daily Living Adult Automation Behavior modification Body mass Body mass index Body size Calories Chronic obstructive pulmonary disease Clinical trials Counseling Diet Diet, Mediterranean Eating Education Emergency medical services Enrollments Feedback Firefighters Food intake Health risks Humans Intervention Lipids Low calorie Lung diseases Lungs Male Medical treatment Metabolic disorders Metabolic syndrome Metabolic Syndrome - etiology Metabolic Syndrome - prevention & control Metabolism New York New York City Nitric oxide Nutrition research Obesity Occupational Exposure Occupational health Outcome Assessment, Health Care Overweight Particulates Physical activity Pulse Wave Analysis Quality of Life Respiratory function Risk factors Search and rescue September 11 Terrorist Attacks Technology Technology education Wave velocity Weight control Young Adult New York City New York United States > US metabolic syndrome particulate matter World Trade Center lung injury Mediterranean diet metabolomics biomarkers 9/11 firefighters
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Fire Department of New York (FDNY) rescue and recovery workers exposed to World Trade Center (WTC) particulates suffered loss of forced expiratory volume in 1 s (FEV ). Metabolic Syndrome increased the risk of developing WTC-lung injury (WTC-LI) We aim to attenuate the deleterious effects of WTC exposure through a dietary intervention targeting these clinically relevant disease modifiers. We hypothesize that a calorie-restricted Mediterranean dietary intervention will improve metabolic risk, subclinical indicators of cardiopulmonary disease, quality of life, and lung function in firefighters with WTC-LI. To assess our hypothesis, we developed the Food Intake REstriction for Health OUtcome Support and Education (FIREHOUSE), a randomized controlled clinical trial (RCT). Male firefighters with WTC-LI and a BMI > 27 kg/m will be included. We will randomize subjects (1:1) to either: (1) Low Calorie Mediterranean (LoCalMed)-an integrative multifactorial, technology-supported approach focused on behavioral modification, nutritional education that will include a self-monitored diet with feedback, physical activity recommendations, and social cognitive theory-based group counseling sessions; or (2) Usual Care. Outcomes include reduction in body mass index (BMI) (primary), improvement in FEV , fractional exhaled nitric oxide, pulse wave velocity, lipid profiles, targeted metabolic/clinical biomarkers, and quality of life measures (secondary). By implementing a technology-supported LoCalMed diet our FIREHOUSE RCT may help further the treatment of WTC associated pulmonary disease.
Bibliography:	Contributed equally.
ISSN:	1660-4601 1661-7827 1660-4601
DOI:	10.3390/ijerph17186569