Search Results - "Young, Ian S"

Protecting-group-free synthesis as an opportunity for invention by Baran, Phil S, Young, Ian S

“…The use of protecting groups has been, and remains, instrumental in the development of organic synthesis. However, designing protecting-group-free strategies…”
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Synthesis of natural products containing the pyrrolic ring by Young, Ian S, Thornton, Paul D, Thompson, Alison

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TCFH–NMI: Direct Access to N‑Acyl Imidazoliums for Challenging Amide Bond Formations by Beutner, Gregory L, Young, Ian S, Davies, Merrill L, Hickey, Matthew R, Park, Hyunsoo, Stevens, Jason M, Ye, Qingmei

“…Challenging couplings of hindered carboxylic acids with non-nucleophilic amines to form amide bonds can be accomplished in high yields, and in many cases, with…”
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Reproducibility and validity of a food frequency questionnaire among pregnant women in a Mediterranean area by Vioque, Jesús, Navarrete-Muñoz, Eva-María, Gimenez-Monzó, Daniel, García-de-la-Hera, Manuela, Granado, Fernando, Young, Ian S, Ramón, Rosa, Ballester, Ferran, Murcia, Mario, Rebagliato, Marisa, Iñiguez, Carmen

“…Studies exploring the role of diet during pregnancy are still scarce, in part due to the complexity of measuring diet and to the lack of valid instruments. The…”
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A Posteriori Dietary Patterns Are Related to Risk of Type 2 Diabetes: Findings from a Systematic Review and Meta-Analysis by McEvoy, Claire T., PhD, RD, Cardwell, Christopher R., PhD, Woodside, Jayne V., PhD, Young, Ian S., MD, MB, BCh, FRCP, Hunter, Steven J., MD, MB, BCh, FRCP, McKinley, Michelle C., PhD

“…Abstract Our review and meta-analysis examined the association between a posteriori –derived dietary patterns (DPs) and risk of type 2 diabetes mellitus…”
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Fruit and vegetable intake and risk of cardiovascular disease by Woodside, Jayne V., Young, Ian S., McKinley, Michelle C.

“…A high intake of fruit and vegetables (FV) has been shown to be associated with reduced risk of a number of chronic diseases, including CVD. This review aims…”
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Total Synthesis of Palau'amine by Seiple, Ian B, Su, Shun, Young, Ian S, Lewis, Chad A, Yamaguchi, Junichiro, Baran, Phil S

“…Worth the wait: The long anticipated total synthesis of palau'amine has been accomplished by a route featuring highly chemoselective transformations, cascade…”
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Association Between Myopia, Ultraviolet B Radiation Exposure, Serum Vitamin D Concentrations, and Genetic Polymorphisms in Vitamin D Metabolic Pathways in a Multicountry European Study by Williams, Katie M, Bentham, Graham C G, Young, Ian S, McGinty, Ann, McKay, Gareth J, Hogg, Ruth, Hammond, Christopher J, Chakravarthy, Usha, Rahu, Mati, Seland, Johan, Soubrane, Gisele, Tomazzoli, Laura, Topouzis, Fotis, Fletcher, Astrid E

“…Myopia is becoming increasingly common globally and is associated with potentially sight-threatening complications. Spending time outdoors is protective, but…”
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Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA): health assessment protocol, participant profile and patterns of participation by Neville, Charlotte E, Young, Ian S, Kee, Frank, Hogg, Ruth E, Scott, Angela, Burns, Frances, Woodside, Jayne V, McGuinness, Bernadette

“…The Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA) is a prospective, longitudinal study of a representative cohort of older adults…”
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Effect of fruit and vegetable consumption on immune function in older people: a randomized controlled trial by Gibson, Andrew, Edgar, J David, Neville, Charlotte E, Gilchrist, Sarah ECM, McKinley, Michelle C, Patterson, Chris C, Young, Ian S, Woodside, Jayne V

“…Background: Fruit and vegetable (FV) intake, which is often low in older people, is associated with reduced chronic disease risk.Objective: We determined…”
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A High Polyphenol Diet Improves Psychological Well-Being: The Polyphenol Intervention Trial (PPhIT) by Kontogianni, Meropi D, Vijayakumar, Aswathy, Rooney, Ciara, Noad, Rebecca L, Appleton, Katherine M, McCarthy, Danielle, Donnelly, Michael, Young, Ian S, McKinley, Michelle C, McKeown, Pascal P, Woodside, Jayne V

“…Mental ill health is currently one of the leading causes of disease burden worldwide. A growing body of data has emerged supporting the role of diet,…”
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Hypoxia compounds exercise-induced free radical formation in humans; partitioning contributions from the cerebral and femoral circulation by Bailey, Damian M., Rasmussen, Peter, Evans, Kevin A., Bohm, Aske M., Zaar, Morten, Nielsen, Henning B., Brassard, Patrice, Nordsborg, Nikolai B., Homann, Pernille H., Raven, Peter B., McEneny, Jane, Young, Ian S., McCord, Joe M., Secher, Niels H.

“…This study examined to what extent the human cerebral and femoral circulation contribute to free radical formation during basal and exercise-induced responses…”
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Development of a peer support intervention to encourage dietary behaviour change towards a Mediterranean diet in adults at high cardiovascular risk by McEvoy, Claire T, Moore, Sarah E, Appleton, Katherine M, Cupples, Margaret E, Erwin, Christina, Kee, Frank, Prior, Lindsay, Young, Ian S, McKinley, Michelle C, Woodside, Jayne V

“…Mediterranean diet (MD) interventions are demonstrated to significantly reduce cardiovascular disease (CVD) risk but are typically resource intensive and…”
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Dietary Intake of Fruits and Vegetables Improves Microvascular Function in Hypertensive Subjects in a Dose-Dependent Manner by MCCALL, Damian O, MCGARTLAND, Claire P, MCKINLEY, Michelle C, PATTERSON, Chris C, SHARPE, Peter, MCCANCE, David R, YOUNG, Ian S, WOODSIDE, Jayne V

“…Observational evidence has consistently linked increased fruit and vegetable consumption with reduced cardiovascular morbidity; however, there is little direct…”
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Enantioselective Total Syntheses of (−)-Palau’amine, (−)-Axinellamines, and (−)-Massadines by Seiple, Ian B, Su, Shun, Young, Ian S, Nakamura, Akifumi, Yamaguchi, Junichiro, Jørgensen, Lars, Rodriguez, Rodrigo A, O’Malley, Daniel P, Gaich, Tanja, Köck, Matthias, Baran, Phil S

“…Dimeric pyrrole–imidazole alkaloids represent a rich and topologically unique class of marine natural products. This full account will follow the progression…”
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FKBPL and SIRT-1 Are Downregulated by Diabetes in Pregnancy Impacting on Angiogenesis and Endothelial Function by Alqudah, Abdelrahim, Eastwood, Kelly-Ann, Jerotic, Djurdja, Todd, Naomi, Hoch, Denise, McNally, Ross, Obradovic, Danilo, Dugalic, Stefan, Hunter, Alyson J, Holmes, Valerie A, McCance, David R, Young, Ian S, Watson, Chris J, Robson, Tracy, Desoye, Gernot, Grieve, David J, McClements, Lana

“…Diabetes in pregnancy is associated with adverse pregnancy outcomes including preterm birth. Although the mechanisms leading to these pregnancy complications…”
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Vitamins C and E for prevention of pre-eclampsia in women with type 1 diabetes (DAPIT): a randomised placebo-controlled trial by McCance, David R, Prof, Holmes, Valerie A, PhD, Maresh, Michael JA, FRCOG, Patterson, Christopher C, PhD, Walker, James D, MD, Pearson, Donald WM, FRCPE, Young, Ian S, Prof

“…Summary Background Results of several trials of antioxidant use during pregnancy have not shown a reduction in pre-eclampsia, but the effect in women with…”
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Oxidative-Nitrosative Stress and Systemic Vascular Function in Highlanders With and Without Exaggerated Hypoxemia by Bailey, Damian M., PhD, Rimoldi, Stefano F., MD, Rexhaj, Emrush, MD, Pratali, Lorenza, MD, PhD, Salinas Salmòn, Carlos, MD, Villena, Mercedes, MD, McEneny, Jane, PhD, Young, Ian S., MD, Nicod, Pascal, MD, Allemann, Yves, MD, Scherrer, Urs, MD, Sartori, Claudio, MD

“…Background Acute exposure to high altitude stimulates free radical formation in lowlanders, yet whether this persists during chronic exposure in healthy,…”
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Total Syntheses of (±)-Massadine and Massadine Chloride by Su, Shun, Seiple, Ian B, Young, Ian S, Baran, Phil S

“…The total syntheses of the complex pyrrole−imidazole alkaloids (±)−massadine and (±)−massadine chloride is described using a carefully orchestrated sequence of…”
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Total Synthesis of (±)-Axinellamines A and B by O'Malley, Daniel P, Yamaguchi, Junichiro, Young, Ian S, Seiple, Ian B, Baran, Phil S

“…Chemoselective by design: The first total synthesis of members of the axinellamine/palau'amine/massadine class of pyrrole–imidazole alkaloids features…”
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