Search Results - "Young, David C"

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    Computational drug design: a guide for computational and medicinal Chemists by Young, D. C

    Published 2009
    “…A solid perspective on the entire breadth of the field of computational drug design, including every major design technique in use today Explains how the drug…”
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    eBook
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    Oral misoprostol, low dose vaginal misoprostol, and vaginal dinoprostone for labor induction: Randomized controlled trial by Young, David C, Delaney, Tina, Armson, B Anthony, Fanning, Cora

    Published in PloS one (01-01-2020)
    “…To compare effectiveness and safety of oral misoprostol (50 μg every four hours as needed), low dose vaginal misoprostol (25 to 50 μg every six hours as…”
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    Journal Article
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    Incremental net monetary benefit of biologic therapies in moderate to severe asthma: a systematic review and meta-analysis of economic evaluation studies by Veettil, Sajesh K., Vincent, Vanessa, Shufelt, Taylor, Behan, Emma, Syeed, M. Sakil, Thakkinstian, Ammarin, Young, David C., Chaiyakunapruk, Nathorn

    Published in The Journal of asthma (02-09-2023)
    “…This meta-analysis was conducted to quantitatively pool the incremental net benefit (INB) of using biologic therapies as an add-on treatment to standard…”
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    Journal Article
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    A periplasmic cinched protein is required for siderophore secretion and virulence of Mycobacterium tuberculosis by Zhang, Lei, Kent, James E., Whitaker, Meredith, Young, David C., Herrmann, Dominik, Aleshin, Alexander E., Ko, Ying-Hui, Cingolani, Gino, Saad, Jamil S., Moody, D. Branch, Marassi, Francesca M., Ehrt, Sabine, Niederweis, Michael

    Published in Nature communications (26-04-2022)
    “…Iron is essential for growth of Mycobacterium tuberculosis , the causative agent of tuberculosis. To acquire iron from the host, M. tuberculosis uses the…”
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    Journal Article
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    Tuberculostearic Acid Controls Mycobacterial Membrane Compartmentalization by Prithviraj, Malavika, Kado, Takehiro, Mayfield, Jacob A, Young, David C, Huang, Annie D, Motooka, Daisuke, Nakamura, Shota, Siegrist, M Sloan, Moody, D Branch, Morita, Yasu S

    Published in mBio (25-04-2023)
    “…The intracellular membrane domain (IMD) is a laterally discrete region of the mycobacterial plasma membrane, enriched in the subpolar region of the rod-shaped…”
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    Building Molecular Complexity from Quinizarin: Conjoined Coumarins and Coronene Analogs by Węcławski, Marek K., Deperasińska, Irena, Banasiewicz, Marzena, Young, David C., Leniak, Arkadiusz, Gryko, Daniel T.

    Published in Chemistry, an Asian journal (15-05-2019)
    “…The double Knoevenagel condensation of 1,4‐dibenzoyloxyanthraquinone with methyl esters of arylacetic acids affords a series of compounds based upon a…”
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    Journal Article
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    Asymmetric Total Synthesis of Mycobacterial Diacyl Trehaloses Demonstrates a Role for Lipid Structure in Immunogenicity by Holzheimer, Mira, Reijneveld, Josephine F, Ramnarine, Alexandrea K, Misiakos, Georgios, Young, David C, Ishikawa, Eri, Cheng, Tan-Yun, Yamasaki, Sho, Moody, D. Branch, Van Rhijn, Ildiko, Minnaard, Adriaan J

    Published in ACS chemical biology (17-07-2020)
    “…The first asymmetric total synthesis of three structures proposed for mycobacterial diacyl trehaloses, DAT1, DAT2, and DAT3 is reported. The presence of two of…”
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    Journal Article
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    Discovery of deoxyceramides and diacylglycerols as CD1b scaffold lipids among diverse groove-blocking lipids of the human CD1 system by Huang, Shouxiong, Cheng, Tan-Yun, Young, David C, Layre, Emilie, Madigan, Cressida A, Shires, John, Cerundolo, Vincenzo, Altman, John D, Moody, D. Branch

    “…Unlike the dominant role of one class II invariant chain peptide (CLIP) in blocking MHC class II, comparative lipidomics analysis shows that human cluster of…”
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    Journal Article
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    Determinants of Perinatal Mortality and Serious Neonatal Morbidity in the Second Twin by Armson, B Anthony, O’Connell, Colleen, Persad, Vidia, Joseph, K S., Young, David C., Baskett, Thomas F.

    Published in Obstetrics and gynecology (New York. 1953) (01-09-2006)
    “…OBJECTIVE:To identify potential determinants of perinatal mortality and neonatal morbidity among second twins relative to first twins. METHODS:A retrospective…”
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    Journal Article
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    Lipidomic analysis links mycobactin synthase K to iron uptake and virulence in M. tuberculosis by Madigan, Cressida A, Martinot, Amanda Jezek, Wei, Jun-Rong, Madduri, Ashoka, Cheng, Tan-Yun, Young, David C, Layre, Emilie, Murry, Jeffrey P, Rubin, Eric J, Moody, D Branch

    Published in PLoS pathogens (01-03-2015)
    “…The prolonged survival of Mycobacterium tuberculosis (M. tb) in the host fundamentally depends on scavenging essential nutrients from host sources. M. tb…”
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    In Vitro 24-Hour Time-Kill Studies of Vancomycin and Linezolid in Combination versus Methicillin-Resistant Staphylococcus aureus by RANI SINGH, Shveta, BACON, Alfred E, YOUNG, David C, COUCH, Kimberly A

    Published in Antimicrobial Agents and Chemotherapy (01-10-2009)
    “…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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    Ultralong C100 mycolic acids support the assignment of Segniliparus as a new bacterial genus by Hong, Sunhee, Cheng, Tan-Yun, Layre, Emilie, Sweet, Lindsay, Young, David C, Posey, James E, Butler, W Ray, Moody, D Branch

    Published in PloS one (14-06-2012)
    “…Mycolic acid-producing bacteria isolated from the respiratory tract of human and non-human mammals were recently assigned as a distinct genus, Segniliparus,…”
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    Mycobacterium tuberculosis SigM Positively Regulates Esx Secreted Protein and Nonribosomal Peptide Synthetase Genes and Down Regulates Virulence-Associated Surface Lipid Synthesis by RAMAN, Sahadevan, XIAOLING PUYANG, CHENG, Tan-Yun, YOUNG, David C, MOODY, D. Branch, HUSSON, Robert N

    Published in Journal of Bacteriology (01-12-2006)
    “…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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    The pharmacokinetics and pharmacodynamics of continuous infusion vancomycin in adult people with cystic fibrosis by Lindley, Bryn, Bhakta, Zubin, Leclair, Laurie, Young, David C.

    Published in Pediatric pulmonology (01-01-2024)
    “…Background The American Thoracic Society Guidelines recommend vancomycin as first line option for treatment of methicillin‐resistant Staphylococcus aureus. Two…”
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    Journal Article
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