Search Results - "Young, Colin R."

C57BL/6J mice exposed to perfluorooctanoic acid demonstrate altered immune responses and increased seizures after Theiler's murine encephalomyelitis virus infection by Pérez Gómez, Aracely A, Wang, Meichen, Kochan, Kelli, Amstalden, Katia, Young, Colin R, Welsh, C Jane, Phillips, Timothy D, Brinkmeyer-Langford, Candice L

“…Neurological diseases can stem from environmental influences such as antecedent viral infections or exposure to potential toxicants, some of which can trigger…”
Get full text

Host genetic diversity drives variable central nervous system lesion distribution in chronic phase of Theiler's Murine Encephalomyelitis Virus (TMEV) infection by Lawley, Koedi S, Rech, Raquel R, Elenwa, Faith, Han, Gang, Perez Gomez, Aracely A, Amstalden, Katia, Welsh, C Jane, Young, Colin R, Threadgill, David W, Brinkmeyer-Langford, Candice L

“…Host genetic background is a significant driver of the variability in neurological responses to viral infection. Here, we leverage the genetically diverse…”
Get full text

Resilience in Long-Term Viral Infection: Genetic Determinants and Interactions by Brinkmeyer-Langford, Candice, Amstalden, Katia, Konganti, Kranti, Hillhouse, Andrew, Lawley, Koedi, Perez-Gomez, Aracely, Young, Colin R, Welsh, C Jane, Threadgill, David W

“…Virus-induced neurological sequelae resulting from infection by Theiler's murine encephalomyelitis virus (TMEV) are used for studying human conditions ranging…”
Get full text

Viral Clearance and Neuroinflammation in Acute TMEV Infection Vary by Host Genetic Background by Lawley, Koedi S, Rech, Raquel R, Perez Gomez, Aracely A, Hopkins, Laura, Han, Gang, Amstalden, Katia, Welsh, C Jane, Young, Colin R, Jones-Hall, Yava, Threadgill, David W, Brinkmeyer-Langford, Candice L

“…A wide range of viruses cause neurological manifestations in their hosts. Infection by neurotropic viruses as well as the resulting immune response can…”
Get full text

Comparison of Body Composition Assessed by Dual-Energy X-Ray Absorptiometry and BMI in Current and Former U.S. Navy Service Members by Gasier, Heath G, Hughes, Linda M, Young, Colin R, Richardson, Annely M

“…Little is known of the diagnostic accuracy of BMI in classifying obesity in active duty military personnel and those that previously served. Thus, the primary…”
Get full text

Evaluating Contemporary and Future-Scenario Substantial-Precipitation Events in the Missouri River Basin Using Object-Oriented Analysis by Brandon J. Fisel, Nathan E. Erickson, Colin R. Young, Ada L. Ellingworth, William J. Gutowski

“…The Missouri River Basin is the largest single river basin in the United States, and, as such, it plays an important role in natural ecosystems as well as the…”
Get full text

Serum Cytokines Predict Neurological Damage in Genetically Diverse Mouse Models by Pérez Gómez, Aracely A, Karmakar, Moumita, Carroll, Raymond J, Lawley, Koedi S, Amstalden, Katia, Young, Colin R, Threadgill, David W, Welsh, C Jane, Brinkmeyer-Langford, Candice

“…Viral infections contribute to neurological and immunological dysfunction driven by complex genetic networks. Theiler's murine encephalomyelitis virus (TMEV)…”
Get full text

Genetic and immunological contributors to virus-induced paralysis by Perez Gomez, Aracely A., Karmakar, Moumita, Carroll, Raymond J., Lawley, Koedi S., Amstalden, Katia, Young, Colin R., Threadgill, David W., Welsh, C. Jane, Brinkmeyer-Langford, Candice

“…Infection by a single virus can evoke diverse immune responses, resulting in different neurological outcomes, depending on the host's genetic background. To…”
Get full text

The Efficacy of Vitamin D Supplementation During a Prolonged Submarine Patrol by Gasier, Heath G., Gaffney-Stomberg, Erin, Young, Colin R., McAdams, Douglas C., Lutz, Laura J., McClung, James P.

“…Submariners spend prolonged periods submerged without sunlight exposure and may benefit from vitamin D supplementation to maintain vitamin D status. The…”
Get full text

Cardiometabolic Health in Submariners Returning from a 3-Month Patrol by Gasier, Heath G, Young, Colin R, Gaffney-Stomberg, Erin, McAdams, Douglas C, Lutz, Laura J, McClung, James P

“…Confined space, limited exercise equipment, rotating shift work and reduced sleep may affect cardiometabolic health in submariners. To test this hypothesis, 53…”
Get full text

Liposarcoma of the thigh with mixed calcification and ossification by Child, Jeremy R., MD, Young, Colin R., MC, USN, Amini, Behrang, MD, PhD

“…Abstract Liposarcoma is one of the most common soft-tissue sarcomas. Calcification and ossification can occur in liposarcoma; however, the presence of both…”
Get full text

An Enigmatic Case of Skeletal Fluorosis: Inhalant-Induced Toxicity by DeMarco, Kara M, Major, Joshua W, Young, Colin R, Hassantoufighi, Arash

“…Skeletal fluorosis is more common in the developing world, but is occasionally seen in the United States. We present radiographic, scintigraphic, CT, and…”
Get full text

Blastocystis and Schistosomiasis Coinfection in a Patient with Chronic Kidney Disease by Young, Colin R., Yeo, Fred E.

“…Chronic kidney disease (CKD) and end-stage renal disease (ESRD) represent a spectrum of impaired immunity with effects on cellular immunity, soluble immune…”
Get full text

Altered FDG Biodistribution in Subcutaneous White Fat on PET/CT Following l-Asparaginase Chemotherapy by Young, Colin R., Kulon, Michal E., Boustani, Anne Marie, Pucar, Darko

“…ABSTRACTA 13-year-old boy with mediastinal T-cell lymphoblastic lymphoma demonstrated an altered biodistribution with diffuse activity in subcutaneous white…”
Get full text

Antecedent presentation of neurological phenotypes in the Collaborative Cross reveals four classes with complex sex-dependencies by Eldridge, Raena, Osorio, Daniel, Amstalden, Katia, Edwards, Caitlin, Young, Colin R., Cai, James J., Konganti, Kranti, Hillhouse, Andrew, Threadgill, David W., Welsh, C. Jane, Brinkmeyer-Langford, Candice

“…Antecedent viral infection may contribute to increased susceptibility to several neurological diseases, such as multiple sclerosis and Parkinson’s disease…”
Get full text

Circulating neutrophil activation in dogs with naturally occurring spinal cord injury secondary to intervertebral disk herniation by Van Sandt, Rae L, Welsh, C Jane, Jeffery, Nick D, Young, Colin R, McCreedy, Dylan A, Wright, Gus A, Boudreau, C Elizabeth, Levine, Gwendolyn J, Levine, Jonathan M

“…To investigate the time course of circulating neutrophil priming and activity in dogs with spinal cord injury secondary to intervertebral disk herniation that…”
Get full text

Bilateral End-Organ Endophthalmitis in Setting of Serratia marcescens Urosepsis on 18F-FDG PET/CT by Makusha, Lovemore P., Young, Colin R., Agarwal, Daniel R., Pucar, Darko

“…ABSTRACTEndogenous endophthalmitis is an uncommon infection of the internal tissues of the eye resulting from a bloodborne infection. We present the case of an…”
Get full text

At-Sea Trial of 24-h-Based Submarine Watchstanding Schedules with High and Low Correlated Color Temperature Light Sources by Young, Colin R., Jones, Geoffrey E., Figueiro, Mariana G., Soutière, Shawn E., Keller, Matthew W., Richardson, Annely M., Lehmann, Benjamin J., Rea, Mark S.

“…United States Navy submariners have historically lived with circadian disruption while at sea due to 18-h-based watchschedules. Previous research demonstrated…”
Get full text

Biodistribution, Tumor Detection, and Radiation Dosimetry of 18 F-5-Fluoro-2'-Deoxycytidine with Tetrahydrouridine in Solid Tumors by Young, Colin R, Adler, Stephen, Eary, Janet F, Lindenberg, M Liza, Jacobs, Paula M, Collins, Jerry, Kummar, Shivaani, Kurdziel, Karen A, Choyke, Peter L, Mena, Esther

“…In preclinical studies, 5-fluoro-2'-deoxycytidine (FdCyd), an inhibitor of DNA methyltransferase and DNA hypermethylation, has shown treatment efficacy against…”
Get full text

Biodistribution, Tumor Detection, and Radiation Dosimetry of 18F-5-Fluoro-2′-Deoxycytidine with Tetrahydrouridine in Solid Tumors by Young, Colin R, Adler, Stephen, Eary, Janet F, Lindenberg, M Liza, Jacobs, Paula M, Collins, Jerry, Kummar, Shivaani, Kurdziel, Karen A, Choyke, Peter L, Mena, Esther

“…In preclinical studies, 5-fluoro-2′-deoxycytidine (FdCyd), an inhibitor of DNA methyltransferase and DNA hypermethylation, has shown treatment efficacy against…”
Get full text