Search Results - "Young, Chainllie"

Subanesthetic Doses of Propofol Induce Neuroapoptosis in the Infant Mouse Brain by Cattano, Davide, Young, Chainllie, Straiko, Megan M.W., Olney, John W.

“…Drugs that block N-methyl-d-aspartate glutamate receptors or that promote γ-aminobutyric acid type A inhibition trigger neuroapoptosis in the developing rodent…”
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Potential of ketamine and midazolam, individually or in combination, to induce apoptotic neurodegeneration in the infant mouse brain by Young, Chainllie, Jevtovic‐Todorovic, Vesna, Qin, Yue‐Qin, Tenkova, Tatyana, Wang, Haihui, Labruyere, Joann, Olney, John W

“…Recently, it was reported that anesthetizing infant rats for 6 h with a combination of anesthetic drugs (midazolam, nitrous oxide, isoflurane) caused…”
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Neuroapoptosis in the infant mouse brain triggered by a transient small increase in blood alcohol concentration by Young, Chainllie, Olney, John W.

“…Exposure of infant rats or mice to ethanol on a single occasion during the period of rapid synaptogenesis can cause extensive apoptotic neurodegeneration…”
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Isoflurane-induced neuroapoptosis in the developing brain of nonhypoglycemic mice by Johnson, Stephen A, Young, Chainllie, Olney, John W

“…Drugs that suppress neuronal activity, including general anesthetics used in pediatric and obstetric medicine, trigger neuroapoptosis in the developing rodent…”
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Lithium Protects against Anesthesia-induced Developmental Neuroapoptosis by STRAIKO, Megan M. W, YOUNG, Chainllie, CATTANO, Davide, CREELEY, Catherine E, HAIHUI WANG, SMITH, Derek J, JOHNSON, Stephen A, LI, Erin S, OLNEY, John W

“…Ethanol and anesthetic drugs trigger neuroapoptosis in the developing mouse brain. Recently, it was found that ethanol-induced neuroapoptosis is preceded by…”
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Apoptotic neurodegeneration induced by ethanol in neonatal mice is associated with profound learning/memory deficits in juveniles followed by progressive functional recovery in adults by Wozniak, David F., Hartman, Richard E., Boyle, Maureen P., Vogt, Sherri K., Brooks, Ashley R., Tenkova, Tatyana, Young, Chainllie, Olney, John W., Muglia, Louis J.

“…Administration of ethanol to rodents during the synaptogenesis period induces extensive apoptotic neurodegeneration in the developing brain. This neurotoxicity…”
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Potential of xenon to induce or to protect against neuroapoptosis in the developing mouse brain by Cattano, Davide, Williamson, Peter, Fukui, Kimiko, Avidan, Michael, Evers, Alex S., Olney, John W., Young, Chainllie

“…Purpose: Drugs that suppress neuronal activity, including all general anesthetics that have been tested thus far (ketamine, midazolam, isoflurane, propofol,…”
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Cathepsin D Deficiency Induces Persistent Neurodegeneration in the Absence of Bax-Dependent Apoptosis by Shacka, John J, Klocke, Barbara J, Young, Chainllie, Shibata, Masahiro, Olney, John W, Uchiyama, Yasuo, Saftig, Paul, Roth, Kevin A

“…Neuronal ceroid lipofuscinosces/Batten disease (NCL) is a devastating group of neurodegenerative diseases caused by genetic disruptions in lysosomal function…”
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Ethanol causes and lithium prevents neuroapoptosis and suppression of pERK in the infant mouse brain by Young, Chainllie, Straiko, Megan M.W, Johnson, Stephen A, Creeley, Catherine, Olney, John W

“…Abstract Transient exposure of immature animals during the brain growth spurt period to ethanol triggers neuroapoptosis in the developing brain. Here we report…”
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Role of caspase-3 in ethanol-induced developmental neurodegeneration by Young, Chainllie, Roth, Kevin A., Klocke, Barbara J., West, Tim, Holtzman, David M., Labruyere, Joann, Qin, Yue-Qin, Dikranian, Krikor, Olney, John W.

“…Acute, transient exposure to ethanol causes a widespread pattern of caspase-3 activation and neuroapoptosis in the developing rodent brain. To determine…”
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Adenylyl cyclases types 1 and 8 promote pro-survival pathways after ethanol exposure in the neonatal brain by Conti, Alana C, Young, Chainllie, Olney, John W, Muglia, Louis J

“…Abstract Although a wide range of developmental disabilities following fetal alcohol exposure are observed clinically, the molecular factors that determine the…”
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Excitotoxic versus apoptotic mechanisms of neuronal cell death in perinatal hypoxia/ischemia by Young, Chainllie, Tenkova, Tatyana, Dikranian, Krikor, Olney, John W

“…Hypoxic/ischemic (H/I) neuronal degeneration in the developing central nervous system (CNS) is mediated by an excitotoxic mechanism, and it has also been…”
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ACTH therapy for Taiwanese children with West syndrome—efficacy and impact on long-term prognosis by Lin, Haung-Chi, Young, Chainllie, Wang, Pen-Jung, Lee, Wang-Tso, Shen, Yu-Zen

“…To study the efficacy of adrenocorticotrophic hormone (ACTH) in treating Taiwanese children with West syndrome (WS) and the impact on long-term prognosis, 66…”
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Docosahexaenoic acid inhibits synaptic transmission and epileptiform activity in the rat hippocampus by Young, Chainllie, Gean, Po-Wu, Chiou, Lih-Chu, Shen, Yu-Zen

“…Docosahexaenoic acid (DHA) has been suggested to be required for neuronal development and synaptic plasticity. However, in view of the fact that DHA…”
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National survey of West syndrome in Taiwan by Young, Chainllie

“…In the fall of 2000, the Taiwan Child Neurology Society performed a retrospective survey of West syndrome that occurred in 1998 and 1999 in Taiwan…”
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Cancellation of low-frequency stimulation-induced long-term depression by docosahexaenoic acid in the rat hippocampus by Young, Chainllie, Gean, Po-Wu, Wu, Shang-Peng, Lin, Chih-Hung, Shen, Yu-Zen

“…The effects of docosahexaenoic acid (DHA) on low-frequency stimulation (LFS)-induced long-term depression (LTD) were investigated in the CA 1 subfield of rat…”
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Early epileptic encephalopathy with suppression burst electroencephalographic pattern – an analysis of eight Taiwanese patients by Chen, Peir-Taur, Young, Chainllie, Lee, Wang-Tso, Wang, Pen-Jung, Peng, Steven Shinnforng, Shen, Yu-Zen

“…Early epileptic encephalopathy with suppression burst (SB) comprises two distinct epileptic syndromes, early infantile epileptic encephalopathy (EIEE) and…”
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Bilateral central retinal vein occlusion with multiple intracerebral hemorrhage in a neonate by Chen, Chien-Yi, Tsao, Po-Nien, Young, Chainllie, Peng, Steven S.F, Tsou, Kuo-Inn

“…Central retinal vein occlusion and intracerebral hemorrhage are rare diseases during infancy and are both related to venous thrombosis. We present the case of…”
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Adult-Onset Pica Leading to Acute Intestinal Obstruction by Stroman, Devin, MD, Young, Chainllie, MD, PhD, Rubano, Angelo R., MD, Pinkhasov, Aaron, MD

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Selective enhancement of l-type calcium currents by corticotropin in acutely isolated rat amygdala neurons by Young, C, Huang, Y, Lin, C, Shen, Y, Gean, P

“…The modulation of voltage-dependent calcium currents (I(Ca)) by corticotropin was studied in acutely dissociated rat amygdala neurons using whole-cell,…”
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