Search Results - "Young, Betty M."

Chronic ethanol induces inhibition of antigen-specific CD8+ but not CD4+ immunodominant T cell responses following Listeria monocytogenes inoculation by Gurung, Prajwal, Young, Betty M., Coleman, Ruth A., Wiechert, Susan, Turner, Lucas E., Ray, Nancy B., Waldschmidt, Thomas J., Legge, Kevin L., Cook, Robert T.

“…Chronic ethanol consumption results in immunodeficiency. Previous work with chronic ethanol‐fed mice has shown reduced splenic weight and cellularity,…”
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The TGF‐β response to Leishmania chagasi in the absence of IL‐12 by Wilson, Mary E., Recker, Thomas J., Rodriguez, Nilda E., Young, Betty M., Burnell, Kindra K., Streit, Judy A., Kline, Joel N.

“…Cure of leishmaniasis requires a type 1 immune response characterized by IFN‐γ production. Leishmania major infection leads to a type 2 response suppressing…”
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A practical method of chronic ethanol administration in mice by Coleman, Ruth A, Young, Betty M, Turner, Lucas E, Cook, Robert T

“…Mice provide a useful model for the study of immune deficiency caused by chronic alcohol abuse. Their suitability is related to several factors, including in…”
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Polyclonal and antigen-specific responses of T cells and T cell subsets by Young, Betty M, Wiechert, Susan, Coleman, Ruth A, Gurung, Prajwal, Cook, Robert T

“…Evaluation of the functional responses of T cells is of importance in determining the mechanism(s) of immunodeficiency resulting from chronic alcohol abuse and…”
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Antigen-specific CD8+ T cell response are reduced by chronic ethanol and by TLR agonists: CD8+ T cell alterations by Gurung, Prajwal, McGill, Jodi, Young, Betty M, Coleman, Ruth A, Legge, Kevin L, Cook, Robert T

“…CD8+ T cells from the ethanol mice have reduced expression of IL2Rβ, and reduced expression of the activation markers KLRG1 and NKG2D. Because chronic ethanol…”
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CD8+ T cell responses in short and long-term chronic ethanol consuming mice by Gurung, Prajwal, Young, Betty M., Coleman, Ruth A., Wiechert, Susan, Ray, Nancy B., Cook, Robert T.

“…Previous work in our lab, evaluating antigen specific CD4+ T cell responses in C57BL/6 female mice after Listeria monocytogenes inoculation have failed to show…”
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Reduced antigen-specific CD8+ T cell responses as a result of increased bacterial translocation in chronic ethanol consuming mice (129.17) by Gurung, Prajwal, Young, Betty M, Turner, Lucas E, Coleman, Ruth A, Wiechert, Susan, Waldschmidt, Thomas J, Legge, Kevin L, Cook, Robert T

“…Abstract Chronic ethanol consumption leads to increased translocation of bacterial products such as LPS and PGN. Previously, we have shown that chronic ethanol…”
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The importance of TGF-beta in murine visceral leishmaniasis by Wilson, M E, Young, B M, Davidson, B L, Mente, K A, McGowan, S E

“…IFN-gamma is critical for the cure of leishmaniasis in humans and mice. BALB/c mice are genetically susceptible to infection with the visceralizing species of…”
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Fetal/neonatal ethanol exposure irreversibly alters immune parameters in young mice (36.28) by Fan, Ji, Young, Betty M, Cook, Robert T, Edsen, Michelle R, Legge, Kevin L, Waldschmidt, Thomas J, Tygrett, Lorraine T, Schlueter, Annette J

“…Abstract Chronic ethanol ingestion has been shown to impair immune defensive function of adult hosts to invading organisms. Children born to alcoholic mothers…”
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Local suppression of IFN-gamma in hepatic granulomas correlates with tissue-specific replication of Leishmania chagasi by Wilson, ME, Sandor, M, Blum, AM, Young, BM, Metwali, A, Elliott, D, Lynch, RG, Weinstock, JV

“…BALB/c mice are susceptible to infection with the visceralizing species of Leishmania, Leishmania chagasi. The parasite load initially rises in the liver and…”
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The TGF-? response toLeishmania chagasi in the absence of IL-12 by Wilson, Mary?E., Recker, Thomas?J., Rodriguez, Nilda?E., Young, Betty?M., Burnell, Kindra?K., Streit, Judy?A., Kline, Joel?N.

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The Importance of TGF-{beta} in Murine Visceral Leishmaniasis by Wilson, Mary E, Young, Betty M, Davidson, Beverly L, Mente, Kimberly A, McGowan, Stephen E

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