Search Results - "Young, AA"

CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancer by Chipumuro, Edmond, Marco, Eugenio, Christensen, Camilla L., Kwiatkowski, Nicholas, Zhang, Tinghu, Hatheway, Clark M., Abraham, Brian J., Sharma, Bandana, Yeung, Caleb, Altabef, Abigail, Perez-Atayde, Antonio, Wong, Kwok-Kin, Yuan, Guo-Cheng, Gray, Nathanael S., Young, Richard A., George, Rani E.

“…The MYC oncoproteins are thought to stimulate tumor cell growth and proliferation through amplification of gene transcription, a mechanism that has thwarted…”
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Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors by Zhang, Tinghu, Kwiatkowski, Nicholas, Olson, Calla M, Dixon-Clarke, Sarah E, Abraham, Brian J, Greifenberg, Ann K, Ficarro, Scott B, Elkins, Jonathan M, Liang, Yanke, Hannett, Nancy M, Manz, Theresa, Hao, Mingfeng, Bartkowiak, Bartlomiej, Greenleaf, Arno L, Marto, Jarrod A, Geyer, Matthias, Bullock, Alex N, Young, Richard A, Gray, Nathanael S

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Quantifying ultra-rare pre-leukemic clones via targeted error-corrected sequencing by Young, A L, Wong, T N, Hughes, A E O, Heath, S E, Ley, T J, Link, D C, Druley, T E

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Noninvasive quantification of cerebrovascular pressure changes using 4D Flow MRI by Marlevi, David, Schollenberger, Jonas, Aristova, Maria, Ferdian, Edward, Ma, Yue, Young, Alistair A., Edelman, Elazer R., Schnell, Susanne, Figueroa, C. Alberto, Nordsletten, David A.

“…Purpose Hemodynamic alterations are indicative of cerebrovascular disease. However, the narrow and tortuous cerebrovasculature complicates image‐based…”
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Stress-restress: Effects on ACTH and fast feedback by Liberzon, Israel, Krstov, Melissa, Young, Elizabeth A.

“…Glucocorticoid secretion is tightly regulated by negative feedback. Glucocorticoid feedback has been found to be altered in depression and post-traumatic…”
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Super-resolution 4D flow MRI to quantify aortic regurgitation using computational fluid dynamics and deep learning by Long, Derek, McMurdo, Cameron, Ferdian, Edward, Mauger, Charlène A., Marlevi, David, Nash, Martyn P., Young, Alistair A.

“…Changes in cardiovascular hemodynamics are closely related to the development of aortic regurgitation (AR), a type of valvular heart disease. Metrics derived…”
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Left ventricular dimensions and mass measurement from 3D echocardiography: are we there yet? by Quill, G, Zhao, D, Gilbert, K, Wang, VY, Legget, ME, Ruygrok, PN, Doughty, RN, Young, AA, Nash, MP

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Pharmacology of exenatide (synthetic exendin-4): a potential therapeutic for improved glycemic control of type 2 diabetes by Nielsen, Loretta L., Young, Andrew A., Parkes, David G.

“…Exenatide (synthetic exendin-4), glucagon-like peptide-1 (GLP-1), and GLP-1 analogues have actions with the potential to significantly improve glycemic control…”
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Automated analysis of 3D-echocardiography using spatially registered patient-specific CMR meshes by Zhao, D, Ferdian, E, Maso Talou, GD, Quill, GM, Gilbert, K, Babarenda Gamage, TP, Wang, VY, Pedrosa, J, D"hooge, J, Legget, M, Ruygrok, PN, Doughty, RN, Camara, O, Young, AA, Nash, MP

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Exenatide (Exendin-4) Improves Insulin Sensitivity and β-Cell Mass in Insulin-Resistant Obese fa/fa Zucker Rats Independent of Glycemia and Body Weight by Gedulin, Bronislava R, Nikoulina, Svetlana E, Smith, Pamela A, Gedulin, George, Nielsen, Loretta L, Baron, Alain D, Parkes, David G, Young, Andrew A

“…The effects of the incretin mimetic exenatide (exendin-4) on metabolic parameters, insulin sensitivity, and β-cell mass were examined in nondiabetic,…”
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Shear properties of passive ventricular myocardium by Dokos, Socrates, Smaill, Bruce H, Young, Alistair A, LeGrice, Ian J

“…We examined the shear properties of passive ventricular myocardium in six pig hearts. Samples (3 x 3 x 3 mm) were cut from adjacent regions of the lateral left…”
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Hot, humid air decontamination of a C‐130 aircraft contaminated with spores of two acrystalliferous Bacillus thuringiensis strains, surrogates for Bacillus anthracis by Buhr, T.L., Young, A.A., Bensman, M., Minter, Z.A., Kennihan, N.L., Johnson, C.A., Bohmke, M.D., Borgers‐Klonkowski, E., Osborn, E.B., Avila, S.D., Theys, A.M.G., Jackson, P.J.

“…Aim To develop test methods and evaluate survival of Bacillus thuringiensis kurstaki cry− HD‐1 and B. thuringiensis Al Hakam spores after exposure to hot,…”
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Diosgenin-induced cognitive enhancement in normal mice is mediated by 1,25D3-MARRS by Tohda, Chihiro, Lee, Young-A, Goto, Yukiori, Nemere, Ilka

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PS-097 Adult Survivors Of Fetal Anaemia Have Increased Cardiovascular Risk: Findings From A Cohort Study Of Intrauterine Transfusion Recipients: Abstract PS-097 Table 1 by Wallace, AH, Dalziel, SR, Cowan, BR, Young, AA, Thornburg, KL, Harding, JE

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Adult survivors of fetal anaemia have increased cardiovascular risk: findings from a cohort study of intrauterine transfusion recipients by Wallace, AH, Dalziel, SR, Cowan, BR, Young, AA, Thornburg, KL, Harding, JE

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Test method development to evaluate hot, humid air decontamination of materials contaminated with Bacillus anthracis ∆Sterne and B. thuringiensis Al Hakam spores by Buhr, T.L., Young, A.A., Minter, Z.A., Wells, C.M., McPherson, D.C., Hooban, C.L., Johnson, C.A., Prokop, E.J., Crigler, J.R.

“…Aims To develop test methods and evaluate the survival of Bacillus anthracis ∆Sterne and Bacillus thuringiensis Al Hakam spores after exposure to hot, humid…”
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Test methods and response surface models for hot, humid air decontamination of materials contaminated with dirty spores of Bacillus anthracis ∆Sterne and Bacillus thuringiensis Al Hakam by Buhr, T.L, Young, A.A, Barnette, H.K, Minter, Z.A, Kennihan, N.L, Johnson, C.A, Bohmke, M.D, DePaola, M, Cora‐Laó, M, Page, M.A

“…AIMS: To develop test methods and evaluate survival of Bacillus anthracis ∆Sterne or Bacillus thuringiensis Al Hakam on materials contaminated with dirty spore…”
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Effects of PYY[3-36] in rodent models of diabetes and obesity by PITTNER, R. A, MOORE, C. X, BHAVSAR, S. P, GEDULIN, B. R, SMITH, P. A, JODKA, C. M, PARKES, D. G, SRIVASTAVA, V. P, YOUNG, A. A

“…Peptide YY (PYY) is a 36 amino-acid peptide secreted from ileal L cells following meals. The cleaved subpeptide PYY[3-36] is biologically active and may…”
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Ralph: A Visible/Infrared Imager for the New Horizons Pluto/Kuiper Belt Mission by Reuter, Dennis C., Stern, S. Alan, Scherrer, John, Jennings, Donald E., Baer, James W., Hanley, John, Hardaway, Lisa, Lunsford, Allen, McMuldroch, Stuart, Moore, Jeffrey, Olkin, Cathy, Parizek, Robert, Reitsma, Harold, Sabatke, Derek, Spencer, John, Stone, John, Throop, Henry, Van Cleve, Jeffrey, Weigle, Gerald E., Young, Leslie A.

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RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo by Levine, Michael, Young, Richard A, Zeitlinger, Julia, Stark, Alexander, Kellis, Manolis, Hong, Joung-Woo, Nechaev, Sergei, Adelman, Karen

“…It is widely assumed that the key rate-limiting step in gene activation is the recruitment of RNA polymerase II (Pol II) to the core promoter. Although there…”
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