Search Results - "Younes, Ramy"

NASH in Lean Individuals by Younes, Ramy, Bugianesi, Elisabetta

“…Nonalcoholic fatty liver disease (NAFLD) is generally associated with obesity and the related comorbidities but it can also develop in subjects with a body…”
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Lean NAFLD: A Distinct Entity Shaped by Differential Metabolic Adaptation by Chen, Fei, Esmaili, Saeed, Rogers, Geraint B., Bugianesi, Elisabetta, Petta, Salvatore, Marchesini, Giulio, Bayoumi, Ali, Metwally, Mayada, Azardaryany, Mahmoud Karimi, Coulter, Sally, Choo, Jocelyn M., Younes, Ramy, Rosso, Chiara, Liddle, Christopher, Adams, Leon A., Craxì, Antonio, George, Jacob, Eslam, Mohammed

“…Background and Aims Nonalcoholic fatty liver disease (NAFLD) affects a quarter of the adult population. A significant subset of patients are lean, but their…”
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S1815 Causes of Death, Mortality Rates, and the Role of Socio-Demographic Risk Factors and Biomarkers in Metabolic Dysfunction-Associated Steatohepatitis Mortality in More Than 18,000 Real World Patients From the United States by Schattenberg, Jörn M., Sartini, Claudio, Herrera, Ronald, Raluy, Mireia, Yates, Mark, Younes, Ramy

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Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis by Govaere, Olivier, Cockell, Simon, Tiniakos, Dina, Queen, Rachel, Younes, Ramy, Vacca, Michele, Alexander, Leigh, Ravaioli, Federico, Palmer, Jeremy, Petta, Salvatore, Boursier, Jerome, Rosso, Chiara, Johnson, Katherine, Wonders, Kristy, Day, Christopher P, Ekstedt, Mattias, Orešič, Matej, Darlay, Rebecca, Cordell, Heather J, Marra, Fabio, Vidal-Puig, Antonio, Bedossa, Pierre, Schattenberg, Jörn M, Clément, Karine, Allison, Michael, Bugianesi, Elisabetta, Ratziu, Vlad, Daly, Ann K, Anstee, Quentin M

“…The mechanisms that drive nonalcoholic fatty liver disease (NAFLD) remain incompletely understood. This large multicenter study characterized the…”
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The European NAFLD Registry: A real-world longitudinal cohort study of nonalcoholic fatty liver disease by Hardy, Timothy, Wonders, Kristy, Younes, Ramy, Aithal, Guruprasad P., Aller, Rocio, Allison, Michael, Bedossa, Pierre, Betsou, Fay, Boursier, Jerome, Brosnan, M. Julia, Burt, Alastair, Cobbold, Jeremy, Cortez-Pinto, Helena, Day, Chris P., Dufour, Jean-Francois, Ekstedt, Mattias, Francque, Sven, Harrison, Stephen, Miele, Luca, Nasr, Patrik, Papatheodoridis, George, Petta, Salvatore, Tiniakos, Dina, Torstenson, Richard, Valenti, Luca, Holleboom, Adriaan G., Yki-Jarvinen, Hannele, Geier, Andreas, Romero-Gomez, Manuel, Ratziu, Vlad, Bugianesi, Elisabetta, Schattenberg, Jörn M., Anstee, Quentin M.

“…Non-Alcoholic Fatty Liver Disease (NAFLD), a progressive liver disease that is closely associated with obesity, type 2 diabetes, hypertension and…”
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Performance of the PRO-C3 collagen neo-epitope biomarker in non-alcoholic fatty liver disease by Boyle, Marie, Tiniakos, Dina, Schattenberg, Jorn M, Ratziu, Vlad, Bugianessi, Elisabetta, Petta, Salvatore, Oliveira, Claudia P, Govaere, Olivier, Younes, Ramy, McPherson, Stuart, Bedossa, Pierre, Nielsen, Mette J, Karsdal, Morten, Leeming, Diana, Kendrick, Stuart, Anstee, Quentin M

“…There is an unmet need for non-invasive biomarkers in non-alcoholic fatty liver disease (NAFLD) that can diagnose advanced disease and identify patients…”
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Presence of Serum Antinuclear Antibodies Does Not Impact Long-Term Outcomes in Nonalcoholic Fatty Liver Disease by Younes, Ramy, Govaere, Olivier, Petta, Salvatore, Miele, Luca, Tiniakos, Dina, Burt, Alastair, David, Ezio, Vecchio, Fabio M., Maggioni, Marco, Cabibi, Daniela, Fracanzani, Anna L., Rosso, Chiara, Blanco, Maria J. Garcia, Armandi, Angelo, Caviglia, Gian Paolo, Zaki, Marco Y. W., Liguori, Antonio, Francione, Paolo, Pennisi, Grazia, Grieco, Antonio, Valenti, Luca, Anstee, Quentin M., Bugianesi, Elisabetta

“…We investigated the longitudinal impact of antinuclear antibody (ANA) on clinical outcomes and survival in nonalcoholic fatty liver disease (NAFLD). ANA were…”
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Should we undertake surveillance for HCC in patients with NAFLD? by Younes, Ramy, Bugianesi, Elisabetta

“…The pandemic of obesity and its related complications is rapidly changing the epidemiology of many types of cancer, including hepatocellular carcinoma (HCC)…”
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Sulfatase-2 from Cancer Associated Fibroblasts: An Environmental Target for Hepatocellular Carcinoma? by Zaki, Marco Y.W., Alhasan, Sari F., Shukla, Ruchi, McCain, Misti, Laszczewska, Maja, Geh, Daniel, Patman, Gillian L., Televantou, Despina, Whitehead, Anna, Maurício, João P., Barksby, Ben, Gee, Lucy M., Paish, Hannah L., Leslie, Jack, Younes, Ramy, Burt, Alastair D., Borthwick, Lee A., Thomas, Huw, Beale, Gary S., Govaere, Olivier, Sia, Daniela, Anstee, Quentin M., Tiniakos, Dina, Oakley, Fiona, Reeves, Helen L.

“…Abstract Introduction: Heparin sulphate proteoglycans in the liver tumour microenvironment (TME) are key regulators of cell signalling, modulated by…”
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Macrophage Markers Do Not Add to the Prediction of Liver Fibrosis by Transient Elastography in Patients With Metabolic Associated Fatty Liver Disease by Kazankov, Konstantin, Rosso, Chiara, Younes, Ramy, Armandi, Angelo, Hagström, Hannes, Møller, Holger Jon, Stål, Per, Bugianesi, Elisabetta, Grønbæk, Henning

“…Non-invasive fibrosis staging is essential in metabolic associated fatty liver disease (MAFLD). Transient elastography (TE) is a well-established method for…”
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A spotlight on pathogenesis, interactions and novel therapeutic options in NAFLD by Younes, Ramy, Bugianesi, Elisabetta

“…In 2018, there have been substantial advances in our understanding of the risk factors for advanced liver disease in nonalcoholic fatty liver disease,…”
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Two Trials of Therapeutics for MASH with Liver Fibrosis. Reply by Loomba, Rohit, Hartman, Mark L, Sanyal, Arun J

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FRI-235 Causes of death, mortality rates, and the role of sociodemographic risk factors and biomarkers in metabolic dysfunction-associated steatohepatitis mortality in more than 18, 000 real world patients from the United States by Schattenberg, Jörn M, Sartini, Claudio, Herrera, Ronald, Raluy, Mireia, Yates, Mark, Younes, Ramy

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WED-197 How many real world patients diagnosed with metabolic dysfunction-associated steatohepatitis meet clinical trial eligibility criteria? Findings from a large cohort study of more than 18, 000 patients from the United States by Schattenberg, Jörn M, Sartini, Claudio, Herrera, Ronald, Raluy, Mireia, Yates, Mark, Younes, Ramy

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FRI-260 Diagnosed prevalence of cardio-renal diseases, mental health disorders, sleep apnea, cancer, and mortality rates in more than 18, 000 patients with metabolic dysfunction-associated steatohepatitis with and without cirrhosis from the United States by Schattenberg, Jörn M., Sartini, Claudio, Herrera, Ronald, Raluy, Mireia, Yates, Mark, Younes, Ramy

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NASH limits anti-tumour surveillance in immunotherapy-treated HCC by Pfister, Dominik, Núñez, Nicolás Gonzalo, Govaere, Olivier, Pinter, Matthias, Szydlowska, Marta, Qiu, Mengjie, Deczkowska, Aleksandra, Weiner, Assaf, Müller, Florian, Sinha, Ankit, Friebel, Ekaterina, Engleitner, Thomas, Lenggenhager, Daniela, Moncsek, Anja, Heide, Danijela, Stirm, Kristin, Kosla, Jan, Kotsiliti, Eleni, Leone, Valentina, Dudek, Michael, Yousuf, Suhail, Inverso, Donato, Singh, Indrabahadur, Teijeiro, Ana, Castet, Florian, Montironi, Carla, Haber, Philipp K., Tiniakos, Dina, Bedossa, Pierre, Cockell, Simon, Younes, Ramy, Marra, Fabio, Schattenberg, Jörn M., Allison, Michael, Bugianesi, Elisabetta, Ratziu, Vlad, D’Alessio, Antonio, Personeni, Nicola, Rimassa, Lorenza, Daly, Ann K., Scheiner, Bernhard, Pomej, Katharina, Kirstein, Martha M., Peck-Radosavljevic, Markus, Hucke, Florian, Finkelmeier, Fabian, Trojan, Jörg, Schulze, Kornelius, Wege, Henning, Koch, Sandra, Weinmann, Arndt, Bueter, Marco, Rössler, Fabian, Siebenhüner, Alexander, Mallm, Jan-Philipp, Umansky, Viktor, Jugold, Manfred, Luedde, Tom, Schietinger, Andrea, Schirmacher, Peter, Emu, Brinda, Augustin, Hellmut G., Billeter, Adrian, Müller-Stich, Beat, Kikuchi, Hiroto, Duda, Dan G., Waldschmidt, Dirk-Thomas, Rahbari, Nuh, Mei, Henrik E., Schulz, Axel Ronald, Ringelhan, Marc, Malek, Nisar, Spahn, Stephan, Bitzer, Michael, Ruiz de Galarreta, Marina, Lujambio, Amaia, Dufour, Jean-Francois, Marron, Thomas U., Kaseb, Ahmed, Kudo, Masatoshi, Huang, Yi-Hsiang, Djouder, Nabil, Wolter, Katharina, Zender, Lars, Decaens, Thomas, Pinato, David J., Rad, Roland, Mertens, Joachim C., Weber, Achim, Unger, Kristian, Meissner, Felix, Roth, Susanne, Jilkova, Zuzana Macek, Claassen, Manfred, Anstee, Quentin M., Amit, Ido, Knolle, Percy, Becher, Burkhard, Llovet, Josep M., Heikenwalder, Mathias

“…Hepatocellular carcinoma (HCC) can have viral or non-viral causes 1 – 5 . Non-alcoholic steatohepatitis (NASH) is an important driver of HCC. Immunotherapy has…”
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Diagnostic accuracy of non-invasive tests for advanced fibrosis in patients with NAFLD: an individual patient data meta-analysis by Mózes, Ferenc Emil, Lee, Jenny A, Selvaraj, Emmanuel Anandraj, Jayaswal, Arjun Narayan Ajmer, Trauner, Michael, Boursier, Jerome, Fournier, Céline, Staufer, Katharina, Stauber, Rudolf E, Bugianesi, Elisabetta, Younes, Ramy, Gaia, Silvia, Lupșor-Platon, Monica, Petta, Salvatore, Shima, Toshihide, Okanoue, Takeshi, Mahadeva, Sanjiv, Chan, Wah-Kheong, Eddowes, Peter J, Hirschfield, Gideon M, Newsome, Philip Noel, Wong, Vincent Wai-Sun, de Ledinghen, Victor, Fan, Jiangao, Shen, Feng, Cobbold, Jeremy F, Sumida, Yoshio, Okajima, Akira, Schattenberg, Jörn M, Labenz, Christian, Kim, Won, Lee, Myoung Seok, Wiegand, Johannes, Karlas, Thomas, Yılmaz, Yusuf, Aithal, Guruprasad Padur, Palaniyappan, Naaventhan, Cassinotto, Christophe, Aggarwal, Sandeep, Garg, Harshit, Ooi, Geraldine J, Nakajima, Atsushi, Yoneda, Masato, Ziol, Marianne, Barget, Nathalie, Geier, Andreas, Tuthill, Theresa, Brosnan, M Julia, Anstee, Quentin Mark, Neubauer, Stefan, Harrison, Stephen A, Bossuyt, Patrick M, Pavlides, Michael

“…Liver biopsy is still needed for fibrosis staging in many patients with non-alcoholic fatty liver disease. The aims of this study were to evaluate the…”
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Monitoring Occurrence of Liver-Related Events and Survival by Transient Elastography in Patients With Nonalcoholic Fatty Liver Disease and Compensated Advanced Chronic Liver Disease by Petta, Salvatore, Sebastiani, Giada, Viganò, Mauro, Ampuero, Javier, Wai-Sun Wong, Vincent, Boursier, Jerome, Berzigotti, Annalisa, Bugianesi, Elisabetta, Fracanzani, Anna Ludovica, Cammà, Calogero, Enea, Marco, Grottes, Marraud des, Di Marco, Vito, Younes, Ramy, Keyrouz, Aline, Mazzola, Sergio, Mendoza, Yuly, Pennisi, Grazia, Romero-Gomez, Manuel, Craxì, Antonio, de Ledinghen, Victor

“…Patients with advanced fibrosis related to nonalcoholic fatty liver disease (NAFLD) are at risk of developing hepatic and extrahepatic complications. We…”
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Caucasian lean subjects with non-alcoholic fatty liver disease share long-term prognosis of non-lean: time for reappraisal of BMI-driven approach? by Younes, Ramy, Govaere, Olivier, Petta, Salvatore, Miele, Luca, Tiniakos, Dina, Burt, Alastair, David, Ezio, Vecchio, Fabio Maria, Maggioni, Marco, Cabibi, Daniela, McLeod, Duncan, Pareja, Maria Jesus, Fracanzani, Anna Ludovica, Aller, Rocio, Rosso, Chiara, Ampuero, Javier, Gallego-Durán, Rocío, Armandi, Angelo, Caviglia, Gian Paolo, Zaki, Marco Y W, Liguori, Antonio, Francione, Paolo, Pennisi, Grazia, Grieco, Antonio, Birolo, Giovanni, Fariselli, Piero, Eslam, Mohammed, Valenti, Luca, George, Jacob, Romero-Gómez, Manuel, Anstee, Quentin Mark, Bugianesi, Elisabetta

“…The full phenotypic expression of non-alcoholic fatty liver disease (NAFLD) in lean subjects is incompletely characterised. We aimed to investigate prevalence,…”
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Diagnostic accuracy of elastography and magnetic resonance imaging in patients with NAFLD: A systematic review and meta-analysis by Selvaraj, Emmanuel Anandraj, Jayaswal, Arjun Narayan Ajmer, Zafarmand, Mohammad Hadi, Vali, Yasaman, Lee, Jenny A., Levick, Christina Kim, Young, Liam Arnold Joseph, Palaniyappan, Naaventhan, Liu, Chang-Hai, Aithal, Guruprasad Padur, Romero-Gómez, Manuel, Tuthill, Theresa A., Anstee, Quentin M., Neubauer, Stefan, Harrison, Stephen A., Bossuyt, Patrick M., Pavlides, Michael, Anstee, Quentin, Daly, Ann, Johnson, Katherine, Cockell, Simon, Bedossa, Pierre, Oakley, Fiona, Cordell, Heather, Day, Chris, Wonders, Kristy, Zafarmand, Hadi, Vali, Yasaman, Lee, Jenny, Ratziu, Vlad, Pais, Raluca, Schattenberg, Jörn, Vidal-Puig, Toni, Vacca, Michele, Rodrigues-Cuenca, Sergio, Allison, Mike, Kamzolas, Ioannis, Hyötyläinen, Tuulia, McGlinchey, Aiden, Mato, Jose M., Millet, Oscar, Dufour, Jean-François, Berzigotti, Annalisa, Pavlides, Michael, Harrison, Stephen, Neubauer, Stefan, Cobbold, Jeremy, Mozes, Ferenc, Akhtar, Salma, Banerjee, Rajarshi, Kelly, Matt, Erpicum, Charlotte, Romero-Gómez, Manuel, Gómez-González, Emilio, Ampuero, Javier, Gallego-Durán, Rocío, Fernández, Isabel, Montero-Vallejo, Rocío, Fisker, Mette Juul, Sinisi, Antonia, Musa, Kishwar, Sandt, Estelle, Tonini, Manuela, Rosso, Chiara, Armandi, Angelo, Marra, Fabio, Gastaldelli, Amalia, Svegliati, Gianluca, Francque, Sven, Vonghia, Luisa, Luukkonen, Panu, van Mil, Saskia, Papatheodoridis, George, Cortez-Pinto, Helena, Petta, Salvatore, Miele, Luca, Geier, Andreas, Aithal, Guru, Wenn, David, Pereira Rodrigues, Cecília Maria, Chaumat, Pierre, Ortiz, Pablo, Duffin, Kevin, Brosnan, Julia, Tuthill, Theresa, Ertle, Judith, Younes, Ramy, Ostroff, Rachel, Alexander, Leigh, Mikkelsen, Lars Friis, Balp, Maria-Magdalena, Jennings, Lori, Loeffler, Juergen, Hanauer, Guido, Fournier, Céline, Pepin, Kay, Ehman, Richard, Myers, Joel, Torstenson, Richard, Doward, Lynda

“…Vibration-controlled transient elastography (VCTE), point shear wave elastography (pSWE), 2-dimensional shear wave elastography (2DSWE), magnetic resonance…”
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