Search Results - "Younah Kim"

Determination of Liraglutide in Rat Plasma Using Selective Liquid Chromatography–Tandem Mass Spectrometry by Younah Kim, Hyoje Jo, Yelim Lee, Soo Yeon Kang, Sangkyu Lee

“…Liraglutide is a medication prescribed for the management of type 2 diabetes and chronic obesity. A simple, sensi- tive, and selective liquid…”
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Characterization of hydrocoptisonine metabolites in human liver microsomes using a high-resolution quadrupole-orbitrap mass spectrometer by Choi, Su Min, Kim, Younah, Lee, Jaeick, Kim, Ju-Hyun, Lee, Taeho, Min, Byung Sun, Kim, Jeong Ah, Lee, Sangkyu

“…Hydrocoptisonine is a new compound that has been isolated from the rhizomes of Coptis chinensis, which belongs to the Ranunculaceae family of Chinese…”
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Characterization of developmental defects in the forebrain resulting from hyperactivated mTOR signaling by integrative analysis of transcriptomic and proteomic data by Shin, Jiheon, Kim, Minhyung, Jung, Hee-Jung, Cha, Hye Lim, Suh-Kim, Haeyoung, Ahn, Sanghyun, Jung, Jaehoon, Kim, YounAh, Jun, Yukyung, Lee, Sanghyuk, Hwang, Daehee, Kim, Jaesang

“…Hyperactivated mTOR signaling in the developing brain has been implicated in multiple forms of pathology including tuberous sclerosis complex (TSC). To date,…”
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A secretome profile indicative of oleate-induced proliferation of HepG2 hepatocellular carcinoma cells by Park, Soyeon, Park, Ji-Hwan, Jung, Hee-Jung, Jang, Jin-Hyeok, Ahn, Sanghyun, Kim, Younah, Suh, Pann-Ghill, Chae, Sehyun, Yoon, Jong Hyuk, Ryu, Sung Ho, Hwang, Daehee

“…Increased fatty acid (FA) is often observed in highly proliferative tumors. FAs have been shown to modulate the secretion of proteins from tumor cells,…”
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Characterization of red ginseng–drug interaction by CYP3A activity increased in high dose administration in mice by Kim, Younah, Jo, Jung Jae, Cho, Piljoung, Shrestha, Riya, Kim, Kyu Min, Ki, Sung Hwan, Song, Kyung‐Sik, Liu, Kwang‐Hyeon, Song, Im‐Sook, Kim, Ju‐Hyun, Lee, Jae‐Mok, Lee, Sangkyu

“…Ginseng (Panax ginseng Meyer) is a popular traditional herbal medicine used worldwide. Patients often take ginseng preparations with other medicines where the…”
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Identification of HYIpro-3-1 Metabolites, a Novel Anti-Inflammatory Compound, in Human Liver Microsomes by Quadrupole-Orbitrap High-Resolution Mass Spectrometry by Honghao Bai, Younah Kim, Sanjita Paudel, Eung-Seok Lee, Sangkyu Lee

“…HYIpro-3-1 is an adjuvant for preventing or treating inflammatory growth diseases. In this study, we identified the metabolic pathway of HYIpro-3-1 in human…”
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Determination of Liraglutide in Rat Plasma Using Selective Liquid Chromatography-Tandem Mass Spectrometry by Younah Kim, Hyoje Jo, Yelim Lee, Soo Yeon Kang, Sangkyu Lee

“…Liraglutide is a medication prescribed for the management of type 2 diabetes and chronic obesity. A simple, sensitive, and selective liquid…”
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Assessing Drug Interaction and Pharmacokinetics of Loxoprofen in Mice Treated with CYP3A Modulators by Paudel, Sanjita, Shrestha, Aarajana, Cho, Piljoung, Shrestha, Riya, Kim, Younah, Lee, Taeho, Kim, Ju-Hyun, Jeong, Tae Cheon, Lee, Eung-Seok, Lee, Sangkyu

“…Loxoprofen (LOX) is a non-selective cyclooxygenase inhibitor that is widely used for the treatment of pain and inflammation caused by chronic and transitory…”
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Identification of HYIpro-3-1 Metabolites, a Novel Anti-Inflammatory Compound, in Human Liver Microsomes by Quadrupole-Orbitrap High-Resolution Mass Spectrometry by Bai, Honghao, Kim, Younah, Paudel, Sanjita, Lee, Eung-Seok, Lee, Sangkyu

“…HYIpro-3-1 is an adjuvant for preventing or treating inflammatory growth diseases. In this study, we identified the metabolic pathway of HYIpro-3-1 in human…”
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In vitro characterization of glycyrol metabolites in human liver microsomes using HR-resolution MS spectrometer coupled with tandem mass spectrometry by Kim, Younah, Shrestha, Riya, Kim, Sunjoo, Kim, Jeong Ah, Lee, Jaeick, Jeong, Tae Cheon, Kim, Ju-Hyun, Lee, Sangkyu

“…1. Glycyrol is a coumestan derivative that is isolated from roots of Glycyrrhiza uralensis. Glycyrol exhibits several biological effects, including…”
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Identification of suberosin metabolites in human liver microsomes by high‐performance liquid chromatography combined with high‐resolution quadrupole–orbitrap mass spectrometer by Paudel, Sanjita, Kim, Younah, Choi, Su Min, Kim, Ju‐Hyun, Bae, Jong‐Sup, Lee, Taeho, Lee, Sangkyu

“…Suberosin is a natural prenylated coumarin derivative isolated from Citropsis articulata. It has various pharmacological properties, especially as an…”
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Characterization of osthenol metabolism in vivo and its pharmacokinetics by Cho, Piljoung, Choi, Su Min, Kim, Younah, Lee, Doo Hyun, Noh, Yeeun, Kim, Sujeong, Kim, Ju-Hyun, Lee, Taeho, Lee, Sangkyu

“…Osthenol, a prenylated coumarin, is a C8-prenylated derivative of umbelliferone isolated from the root of Angelica koreana and Angelica dahurica, an…”
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Evaluation of Red Ginseng-Drug Interaction by CYP450 Induction in High Dose Administration in Mice by Kim, YounAh, Choi, Sumin, Bae, Jong-Sup, Lee, Sangkyu

“…Ginseng–drug interactions at high doses of ginseng are poorly understood. Here we observed the possibility of herb–drug interaction between the Korean red…”
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Selective inhibitory effects of HYIpro‐3‐1 on CYP1A2 in human liver microsomes by Kim, Younah, Kim, Ju‐Hyun, Lee, Taeho, Bae, Jong‐Sup, Jeong, Tae Cheon, Lee, Eung Seok, Lee, Sangkyu

“…CYP1A2 is one of the main Cytochrome P450 enzymes in the human liver associated with the metabolism of several xenobiotics. CYP1A2 is especially involved in…”
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Quantitative Proteomic Analysis of Changes Related to Age and Calorie Restriction in Rat Liver Tissue by Kim, YounAh, Kwon, Oh Kwang, Chae, Sehyun, Jung, Hee‐Jung, Ahn, Sanghyun, Jeon, Ju Mi, Sung, Eunji, Kim, SunJoo, Ki, Sung Hwan, Chung, Ki Wung, Chung, Hae Young, Jung, Young Suk, Hwang, Dae Hee, Lee, Sangkyu

“…Calorie restriction (CR) is the most frequently studied mechanism for increasing longevity, protecting against stress, and delaying age‐associated diseases…”
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