Search Results - "Youil, Rima"
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Improved strategy for mutation detection—a modification to the enzyme mismatch cleavage method
Published in Nucleic acids research (25-12-1995)“…Despite the number of mutation detection systems currently available, the enzyme mismatch cleavage (EMC) method of mutation detection is one of a few…”
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Comparative Immunogenicity in Rhesus Monkeys of DNA Plasmid, Recombinant Vaccinia Virus, and Replication-Defective Adenovirus Vectors Expressing a Human Immunodeficiency Virus Type 1 gag Gene
Published in Journal of Virology (01-06-2003)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Optimization of the Helper-Dependent Adenovirus System for Production and Potency in vivo
Published in Proceedings of the National Academy of Sciences - PNAS (01-02-2000)“…Helper-dependent (HD) adenoviral vectors devoid of all viral coding sequences provide for safe and highly efficient gene transfer with long-lasting transgene…”
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4
Hexon gene switch strategy for the generation of chimeric recombinant adenovirus
Published in Human gene therapy (20-01-2002)“…The usefulness of adenovirus as a vehicle for transgene delivery is limited greatly by the induction of neutralizing anti-adenoviral immunity following the…”
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Screening for Mutations by Enzyme Mismatch Cleavage with T4 Endonuclease VII
Published in Proceedings of the National Academy of Sciences - PNAS (03-01-1995)“…Each of four possible sets of mismatches (G·A/C·T, C·C/ G·G, A·A/T·T, and C·A/G·T) containing the 8 possible single-base-pair mismatches derived from isolated…”
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Rapid method for the characterization of 3′ and 5′ UTRs of influenza viruses
Published in Journal of virological methods (2003)“…A T4 RNA ligase based strategy is demonstrated that allows for the full characterization of 3′ and 5′ UTR regions of negative strand RNA viruses. Negative…”
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Comparative analysis of the effects of packaging signal, transgene orientation, promoters, polyadenylation signals, and E3 region on growth properties of first-generation adenoviruses
Published in Human gene therapy (01-07-2003)“…First-generation adenovectors have been developed for gene therapy and vaccine applications. The construction of these adenovectors has entailed the use of…”
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Protective efficacy of intranasal cold-adapted influenza A/New Caledonia/20/99 (H1N1) vaccines comprised of egg- or cell culture-derived reassortants
Published in Virus research (01-10-2004)“…Live, cold-adapted, temperature-sensitive (ca/ts) Russian influenza A vaccines are prepared in eggs by a 6:2 gene reassortment of the ca/ts donor strain…”
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Detection of 81 of 81 Known Mouse β-Globin Promoter Mutations with T4 Endonuclease VII—The EMC Method
Published in Genomics (San Diego, Calif.) (15-03-1996)“…The enzyme mismatch cleavage (EMC) method relies on the use of the resolvase T4 Endonuclease VII to cleave and thus detect mismatches in heteroduplex DNA…”
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Human Flavin-Containing Monooxygenase Form 3: cDNA Expression of the Enzymes Containing Amino Acid Substitutions Observed in Individuals with Trimethylaminuria
Published in Chemical research in toxicology (01-08-1997)“…Trimethylaminuria is an autosomal recessive human disorder affecting a small part of the population as an inherited polymorphism. Individuals diagnosed with…”
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Enzymatic mutation detection (EMD™) of novel mutations (R565X and R1523X) in the FBN1 gene of patients with Marfan syndrome using T4 endonuclease VII
Published in Human mutation (01-07-2000)“…The Enzymatic Mutation Detection (EMD™) method is a streamlined and improved version of the original Enzymatic Cleavage of Mismatch (EMC) method. EMD is a…”
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Rapid method for the isolation of full length adenoviral genomes by bacterial intermolecular homologous recombination
Published in Journal of virological methods (01-03-2001)“…Recombinant adenoviruses are used widely in gene therapy research. Much work has been carried out to remove specific components of the wild type adenovirus…”
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13
Optimization of the helper-dependent adenovirus system for production and potency invivo
Published in Proceedings of the National Academy of Sciences - PNAS (01-02-2000)“…Helper-dependent (HD) adenoviral vectors devoid of all viral coding sequences provide for safe and highly efficient gene transfer with long-lasting transgene…”
Get full text
Journal Article