Search Results - "Youil, Rima"

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  1. 1

    Improved strategy for mutation detection—a modification to the enzyme mismatch cleavage method by Babon, Jeff J., Youil, Rima, Cotton, Richard G. H.

    Published in Nucleic acids research (25-12-1995)
    “…Despite the number of mutation detection systems currently available, the enzyme mismatch cleavage (EMC) method of mutation detection is one of a few…”
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    Journal Article
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    Optimization of the Helper-Dependent Adenovirus System for Production and Potency in vivo by Sandig, Volker, Youil, Rima, Bett, Andrew J., Franlin, Laura L., Oshima, Masanobu, Maione, Domenico, Wang, Fubao, Metzker, Michael L., Savino, Rocco, Caskey, C. Thomas

    “…Helper-dependent (HD) adenoviral vectors devoid of all viral coding sequences provide for safe and highly efficient gene transfer with long-lasting transgene…”
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    Journal Article
  4. 4

    Hexon gene switch strategy for the generation of chimeric recombinant adenovirus by Youil, Rima, Toner, Timothy J, Su, Qin, Chen, Minchun, Tang, Aimin, Bett, Andrew J, Casimiro, Danilo

    Published in Human gene therapy (20-01-2002)
    “…The usefulness of adenovirus as a vehicle for transgene delivery is limited greatly by the induction of neutralizing anti-adenoviral immunity following the…”
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  5. 5

    Screening for Mutations by Enzyme Mismatch Cleavage with T4 Endonuclease VII by Youil, Rima, Kemper, Borries W., Richard G. H. Cotton

    “…Each of four possible sets of mismatches (G·A/C·T, C·C/ G·G, A·A/T·T, and C·A/G·T) containing the 8 possible single-base-pair mismatches derived from isolated…”
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  6. 6

    Rapid method for the characterization of 3′ and 5′ UTRs of influenza viruses by Szymkowiak, Christopher, Kwan, Wan-Sang, Su, Qin, Toner, Timothy J, Shaw, Alan R, Youil, Rima

    Published in Journal of virological methods (2003)
    “…A T4 RNA ligase based strategy is demonstrated that allows for the full characterization of 3′ and 5′ UTR regions of negative strand RNA viruses. Negative…”
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    Detection of 81 of 81 Known Mouse β-Globin Promoter Mutations with T4 Endonuclease VII—The EMC Method by Youil, Rima, Kemper, Börries, Cotton, Richard G.H.

    Published in Genomics (San Diego, Calif.) (15-03-1996)
    “…The enzyme mismatch cleavage (EMC) method relies on the use of the resolvase T4 Endonuclease VII to cleave and thus detect mismatches in heteroduplex DNA…”
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    Human Flavin-Containing Monooxygenase Form 3:  cDNA Expression of the Enzymes Containing Amino Acid Substitutions Observed in Individuals with Trimethylaminuria by Cashman, John R, Bi, Yi-An, Lin, Jing, Youil, Rima, Knight, Melanie, Forrest, Susan, Treacy, Eileen

    Published in Chemical research in toxicology (01-08-1997)
    “…Trimethylaminuria is an autosomal recessive human disorder affecting a small part of the population as an inherited polymorphism. Individuals diagnosed with…”
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    Enzymatic mutation detection (EMD™) of novel mutations (R565X and R1523X) in the FBN1 gene of patients with Marfan syndrome using T4 endonuclease VII by Youil, Rima, Toner, Timothy J., Bull, Evelyn, Bailey, Anne L., Earl, Christopher D., Dietz, Harry C., Montgomery, Robert A.

    Published in Human mutation (01-07-2000)
    “…The Enzymatic Mutation Detection (EMD™) method is a streamlined and improved version of the original Enzymatic Cleavage of Mismatch (EMC) method. EMD is a…”
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    Rapid method for the isolation of full length adenoviral genomes by bacterial intermolecular homologous recombination by Youil, Rima, Toner, Timothy J, Su, Qin, Kaslow, David C

    Published in Journal of virological methods (01-03-2001)
    “…Recombinant adenoviruses are used widely in gene therapy research. Much work has been carried out to remove specific components of the wild type adenovirus…”
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  13. 13

    Optimization of the helper-dependent adenovirus system for production and potency invivo by Volker Sandig, Rima Youil, Andrew J. Bett, Laura L. Franlin, Masanobu Oshima, Domenico Maione, Fubao Wang, Michael L. Metzker, Rocco Savino, C. Thomas Caskey

    “…Helper-dependent (HD) adenoviral vectors devoid of all viral coding sequences provide for safe and highly efficient gene transfer with long-lasting transgene…”
    Get full text
    Journal Article