Search Results - "Youale, Jenny"

Phototoxicity of low doses of light and influence of the spectral composition on human RPE cells by Françon, Anaïs, Delaunay, Kimberley, Jaworski, Thara, Lebon, Cécile, Picard, Emilie, Youale, Jenny, Behar-Cohen, Francine, Torriglia, Alicia

“…Light is known to induce retinal damage affecting photoreceptors and retinal pigment epithelium. For polychromatic light, the blue part of the spectrum is…”
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Neuroprotective Effects of Transferrin in Experimental Glaucoma Models by Youale, Jenny, Bigot, Karine, Kodati, Bindu, Jaworski, Thara, Fan, Yan, Nsiah, Nana Yaa, Pappenhagen, Nathaniel, Inman, Denise M., Behar-Cohen, Francine, Bordet, Thierry, Picard, Emilie

“…Iron is essential for retinal metabolism, but an excess of ferrous iron causes oxidative stress. In glaucomatous eyes, retinal ganglion cell (RGC) death has…”
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Oral Ursodeoxycholic Acid Crosses the Blood Retinal Barrier in Patients with Retinal Detachment and Protects Against Retinal Degeneration in an Ex Vivo Model by Daruich, Alejandra, Jaworski, Thara, Henry, Hugues, Zola, Marta, Youale, Jenny, Parenti, Léa, Naud, Marie-Christine, Delaunay, Kimberley, Bertrand, Mathilde, Berdugo, Marianne, Kowalczuk, Laura, Boatright, Jeffrey, Picard, Emilie, Behar-Cohen, Francine

“…Rhegmatogenous retinal detachment (RD) is a threatening visual condition and a human disease model for retinal degenerations. Despite successful reattachment…”
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From Rust to Quantum Biology: The Role of Iron in Retina Physiopathology by Picard, Emilie, Daruich, Alejandra, Youale, Jenny, Courtois, Yves, Behar-Cohen, Francine

“…Iron is essential for cell survival and function. It is a transition metal, that could change its oxidation state from Fe to Fe involving an electron transfer,…”
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Transferrin Non-Viral Gene Therapy for Treatment of Retinal Degeneration by Bigot, Karine, Gondouin, Pauline, Bénard, Romain, Montagne, Pierrick, Youale, Jenny, Piazza, Marie, Picard, Emilie, Bordet, Thierry, Behar-Cohen, Francine

“…Dysregulation of iron metabolism is observed in animal models of retinitis pigmentosa (RP) and in patients with age-related macular degeneration (AMD),…”
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Pathophysiology of intraocular haemorrhage: Role of iron in cell death by Picard, Emilie, Youale, Jenny, Daruich‐Matet, Alejandra, Behar‐Cohen, Francine

“…Retinal haemorrhages are present in several retinal pathologies, such as exudative AMD, diabetic retinopathy, or myopic degeneration. As a consequence of…”
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Glyburide confers neuroprotection against age-related macular degeneration (AMD) by Picard, Emilie, Youale, Jenny, Hyman, Max J., Xie, Edward, Achiedo, Seiki, Kaufmann, Gabriel T., Moir, John, Daruich, Alejandra, Crisanti, Patricia, Torriglia, Alicia, Polak, Michel, Behar-Cohen, Francine, Skondra, Dimitra, Berdugo, Marianne

“…Glyburide, a sulfonylurea drug used to treat type 2 diabetes, boasts neuroprotective effects by targeting the sulfonylurea receptor 1 (SUR1) and associated ion…”
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Iron and age-related macular degeneration: a new track by Courtois, Yves, Youale, Jenny, Behar-Cohen, Francine, Picard, Émilie

“…Iron has a fundamental role for cell physiology and especially in retina as a cofactor of many pathways of the visual transduction. A tightly regulated…”
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Oral Ursodeoxycholic acid crosses the blood brain barrier in patients with retinal detachment and protects against retinal degeneration in an ex vivo model by Daruich‐Matet, Alejandra, Jaworski, Thara, Henry, Hugues, Zola, Marta, Youale, Jenny, Parenti, Léa, Naud, Marie‐Christine, Delaunay, Kimberley, Bertrand, Mathilde, Berdugo, Marianne, Kowalczuk, Laura, Boatright, Jeffrey, Picard, Emilie, Behar‐Cohen, francine

“…Purpose The neuroprotective properties of hydrophilic bile acids are recognized but whether their oral administration can benefit to patients with retinal…”
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